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DIM1 rRNA methyltransferase and ribosome maturation factor

Summary

Gene Symbol

Dimt1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

66254

KEGG Gene ID

PubChem

66254

Alliance of Genome Resources

MGI:1913504

Annotation

Keyword

Methyltransferase
Nucleus
RNA-binding
Reference proteome
S-adenosyl-L-methionine
rRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9D0D4	18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase 18S rRNA dimethylase DIM1 dimethyladenosine transferase 1 homolog DIM1 dimethyladenosine transferase 1-like S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
rRNA modification	IEA
rRNA processing	IEA
rRNA methylation	ISS
rRNA methylation	ISO
rRNA methylation	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

methylation [inference]

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation

macromolecule metabolic process [inference]

macromolecule modification [inference]

RNA modification [inference]

rRNA modification

rRNA methylation

RNA methylation [inference]

rRNA methylation

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA modification [inference]

rRNA modification

rRNA methylation

RNA methylation [inference]

rRNA methylation

rRNA metabolic process [inference]

rRNA processing

rRNA modification

rRNA methylation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA modification [inference]

rRNA modification

rRNA methylation

RNA methylation [inference]

rRNA methylation

rRNA metabolic process [inference]

rRNA processing

rRNA modification

rRNA methylation

RNA processing [inference]

rRNA processing

rRNA modification

rRNA methylation

cellular component organization or biogenesis [inference]

cellular component biogenesis [inference]

ribonucleoprotein complex biogenesis [inference]

ribosomal small subunit biogenesis

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

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GO Term	Evidence Code	PMID
nucleoplasm	ISO
nucleoplasm	IEA
nucleolus	ISS
nucleolus	ISO
nucleolus	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

small-subunit processome

ribonucleoprotein complex [inference]

preribosome [inference]

small-subunit processome

cellular anatomical structure [inference]

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
rRNA (adenine-N6,N6-)-dimethyltransferase activity	ISO
rRNA (adenine-N6,N6-)-dimethyltransferase activity	IBA
rRNA (adenine-N6,N6-)-dimethyltransferase activity	IEA
RNA binding
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

catalytic activity, acting on a rRNA [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

rRNA adenine N(6)-methyltransferase

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
S-adenosylmethionine-dependent methyltransferase activity
methylation
rRNA methylation
rRNA methyltransferase activity
transferase activity

Displaying **all 5** entries
InterPro
Ribosomal RNA adenine dimethylase
Ribosomal RNA adenine methylase transferase, N-terminal
Ribosomal RNA adenine methylase transferase, conserved site
Ribosomal RNA adenine methyltransferase KsgA/Erm
S-adenosyl-L-methionine-dependent methyltransferase superfamily