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Guidelines

MIRAGE

Dimethyladenosine transferase

Summary

UniProt ID: Q9D0D4
Gene Symbol: Dimt1 Dimt1l
Gene ID: 66254
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q9D0D4
Re-Glyco: Q9D0D4

Annotation

Keyword: Methyltransferase Nucleus RNA-binding Reference proteome S-adenosyl-L-methionine rRNA processing

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
rRNA methylation	ISS	GO_REF
rRNA methylation	ISO	GO_REF
rRNA methylation	IBA	GO_REF
rRNA methylation	IEA	GO_REF
ribosomal small subunit biogenesis	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

methylation [inference]

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation

macromolecule metabolic process [inference]

macromolecule modification [inference]

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

cellular component organization or biogenesis [inference]

cellular component biogenesis [inference]

ribonucleoprotein complex biogenesis [inference]

ribosomal small subunit biogenesis

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

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GO Term	Evidence Code	Reference
nucleoplasm	ISO	GO_REF
nucleoplasm	IEA	GO_REF GO_REF
nucleolus	ISS	GO_REF
nucleolus	ISO	GO_REF
nucleolus	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

small-subunit processome

ribonucleoprotein complex [inference]

preribosome [inference]

small-subunit processome

cellular anatomical structure [inference]

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
rRNA (adenine-N6,N6-)-dimethyltransferase activity	ISO	GO_REF
rRNA (adenine-N6,N6-)-dimethyltransferase activity	IEA	GO_REF
RNA binding
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	ISS	GO_REF
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	ISO	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

catalytic activity, acting on a rRNA [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPKAKSAASSRRRDRQEQRRELKRAGGLMFNTGIGQHILKNPLIVNSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPLASKLQVLVGDVLKSDLPFFDACVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVQNTVIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
235			G44613TH	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026