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complement component 8, gamma polypeptide

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

69379

PubChem

69379

Alliance of Genome Resources

MGI:88237

Annotation

Keyword

Complement alternate pathway
Disulfide bond
Glycoprotein
Membrane attack complex
Proteomics identification
Pyrrolidone carboxylic acid
Reference proteome
Retinol-binding
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8VCG4
Q9DAC2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
complement activation
complement activation, alternative pathway	IEA
complement activation, classical pathway	IEA
killing of cells of another organism	IEA
positive regulation of immune response	NAS	30552328

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

complement activation

activation of immune response [inference]

complement activation

immune response [inference]

humoral immune response [inference]

complement activation

innate immune response [inference]

complement activation, alternative pathway

cellular process [inference]

cell killing [inference]

killing of cells of another organism

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, alternative pathway

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, alternative pathway

immune response [inference]

humoral immune response [inference]

complement activation

innate immune response [inference]

complement activation, alternative pathway

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, alternative pathway

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, alternative pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

regulation of immune response [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

positive regulation of response to stimulus [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

regulation of immune response [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	IEA
membrane attack complex	ISO
extracellular space	ISO
plasma membrane	NAS	30552328

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

pore complex [inference]

membrane attack complex

plasma membrane protein complex [inference]

membrane attack complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
complement binding	ISO
retinol binding	IEA
protein-containing complex binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

complement binding

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinol binding

small molecule binding [inference]

vitamin binding [inference]

retinol binding

alcohol binding [inference]

retinol binding

protein-containing complex binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Complement component C8 gamma chain

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
complement activation
complement binding

Displaying **all 3** entries
InterPro
Calycin
Complement component C8 gamma chain
Lipocalin/cytosolic fatty-acid binding domain

Ortholog

Displaying entries **21 - 30** of 50 in total

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Species	Gene ID	Orthologous MAtrix
Oryzias latipes	101167000	ORYLA09018
Mustela putorius furo	101690742	MUSPF11421
Heterocephalus glaber	101703244	HETGA26298
Capra hircus	102183974	CAPHI32058
Latimeria chalumnae	102357655	LATCH05764
Pelodiscus sinensis	102450675	PELSI02374
Astyanax mexicanus	103023406	ASTMX09592
Erinaceus europaeus	103112151	ERIEU01726
Callorhinchus milii	103183003	CALMI26432
Rhinopithecus roxellana	104669647	RHIRO01984

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements