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CDP-L-ribitol pyrophosphorylase A

Summary

Gene Symbol

Crppa

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

75847

PubChem

75847

Alliance of Genome Resources

MGI:1923097

Annotation

Keyword

Alternative splicing
Cytoplasm
Nucleotidyltransferase
Proteomics identification
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A1Y7VK76	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein Isoprenoid synthase domain-containing protein
A0A1Y7VM96	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein Isoprenoid synthase domain-containing protein
Q5RJG7	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein Isoprenoid synthase domain-containing protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein glycosylation	IMP	23217742
axon guidance	IMP	23217742
isoprenoid biosynthetic process	IEA
protein O-linked mannosylation	ISS
protein O-linked mannosylation	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

mannosylation [inference]

protein mannosylation [inference]

protein O-linked mannosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytosol	ISS
cytosol	ISO
cytosol	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein homodimerization activity	ISS
protein homodimerization activity	ISO
D-ribitol-5-phosphate cytidylyltransferase activity	ISS
D-ribitol-5-phosphate cytidylyltransferase activity	ISO
D-ribitol-5-phosphate cytidylyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

cytidylyltransferase activity

D-ribitol-5-phosphate cytidylyltransferase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

2-c-methyl-d-erythritol 4-phosphate

Functional Category

I: Lipid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
catalytic activity
cytidylyltransferase activity
nucleotidyltransferase activity

Displaying **all 3** entries
InterPro
4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site
Cytidylyltransferase IspD/TarI
Nucleotide-diphospho-sugar transferases

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110295	autosomal recessive limb-girdle muscular dystrophy type 2U	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 36 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	75847	Xenbase:XB-GENE-1014860
Rattus norvegicus	493574		RATNO35992
Macaca mulatta	714980		MACMU31850
Homo sapiens	729920	Xenbase:XB-GENE-1014860	HUMAN87936
Pan troglodytes	744905		PANTR39748
Equus caballus	100065851		HORSE33072
Oryctolagus cuniculus	100337768		RABIT14426
Callithrix jacchus	100391839		CALJA42914
Pongo abelii	100436260		PONAB33726
Ailuropoda melanoleuca	100477709		AILME14636

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Annotation

OrthoDB (Group)

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Acknowledgements