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solute carrier family 17 (vesicular glutamate transporter), member 7

Summary

Gene Symbol

slc17a7

Organism

Xenopus tropicalis (tropical clawed frog)

External Links

NCBI Gene

780064

KEGG Gene ID

PubChem

780064

Alliance of Genome Resources

Xenbase:XB-GENE-5742677

Annotation

Keyword

Antiport
Cell membrane
Chloride channel
Cytoplasmic vesicle
Glycoprotein
Neurotransmitter transport
Phosphate transport
Reference proteome
Sodium transport
Symport
Synaptosome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q05B21	Solute carrier family 17 member 7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
potassium ion transport	ISS
phosphate ion transport	ISS
chloride transport	ISS
L-glutamate transmembrane transport	ISS
synaptic transmission, glutamatergic	IBA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

intercellular transport [inference]

neurotransmitter loading into synaptic vesicle

transmembrane transport

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport

monoatomic anion transport [inference]

chloride transport

neurotransmitter transport [inference]

neurotransmitter loading into synaptic vesicle

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

intercellular transport [inference]

neurotransmitter loading into synaptic vesicle

inorganic anion transport [inference]

phosphate ion transport

sodium-dependent phosphate transport

chloride transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

transmembrane transport

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

nitrogen compound transport [inference]

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

establishment of localization in cell [inference]

neurotransmitter loading into synaptic vesicle

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

regulation of biological quality [inference]

regulation of synapse structure or activity

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	IEA
synaptic vesicle membrane	ISS
synaptic vesicle membrane	IBA
synaptic vesicle membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

chloride channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

chloride channel complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

cell junction [inference]

synapse

excitatory synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
chloride channel activity	ISS
L-glutamate transmembrane transporter activity	IBA
neurotransmitter transmembrane transporter activity	IBA
sodium:phosphate symporter activity	ISS
potassium:proton antiporter activity	ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

neurotransmitter transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

metal cation:proton antiporter activity [inference]

potassium:proton antiporter activity

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

potassium:proton antiporter activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity

amino acid transmembrane transporter activity [inference]

acidic amino acid transmembrane transporter activity [inference]

L-glutamate transmembrane transporter activity

L-glutamate uniporter activity

L-amino acid transmembrane transporter activity [inference]

L-glutamate transmembrane transporter activity

L-glutamate uniporter activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

phosphate transmembrane transporter activity [inference]

uniporter activity [inference]

membrane potential driven uniporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

antiporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

potassium:proton antiporter activity

carboxylic acid transmembrane transporter activity [inference]

L-amino acid transmembrane transporter activity [inference]

L-glutamate transmembrane transporter activity

L-glutamate uniporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
MFS transporter superfamily
Major facilitator superfamily domain
Major facilitator superfamily

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	140919	MGI:2156052
Mus musculus	72961	MGI:1920211
Rattus norvegicus	84487	RGD:620531
Caenorhabditis elegans	176441	WB:WBGene00010755
Caenorhabditis elegans	176291	WB:WBGene00001135
Caenorhabditis elegans	176442	WB:WBGene00011556
Saccharomyces cerevisiae S288C	850671	SGD:S000003978