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aldo-keto reductase family 1 member A1

Summary

Gene Symbol

Akr1a1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

78959

KEGG Gene ID

PubChem

78959

Alliance of Genome Resources

RGD:68346

Annotation

Keyword

Acetylation
Cell membrane
Cytoplasm
Direct protein sequencing
Glycation
Lipid metabolism
NADP
Oxidoreductase
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P51635	3-DG-reducing enzyme Alcohol dehydrogenase [NADP(+)] Aldehyde reductase Glucuronate reductase Glucuronolactone reductase S-nitroso-CoA reductase
A6JZ88	Alcohol dehydrogenase [NADP(+)] Aldehyde reductase Glucuronate reductase Glucuronolactone reductase S-nitroso-CoA reductase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
lipid metabolic process
D-glucuronate catabolic process to D-xylulose 5-phosphate	ISO
D-glucuronate catabolic process to D-xylulose 5-phosphate	IEA
L-ascorbic acid biosynthetic process	ISO
L-ascorbic acid biosynthetic process	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

aldehyde metabolic process [inference]

aldehyde catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

D-xylulose 5-phosphate metabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

organophosphate metabolic process [inference]

D-xylulose 5-phosphate metabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

catabolic process [inference]

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate catabolic process to D-xylulose 5-phosphate

aldehyde catabolic process

biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

secondary metabolic process [inference]

polyketide metabolic process [inference]

ketone metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lipid metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

doxorubicin metabolic process

tertiary alcohol metabolic process [inference]

doxorubicin metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate catabolic process to D-xylulose 5-phosphate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate catabolic process to D-xylulose 5-phosphate

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate catabolic process to D-xylulose 5-phosphate

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate catabolic process to D-xylulose 5-phosphate

vitamin metabolic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate catabolic process to D-xylulose 5-phosphate

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carbohydrate derivative metabolic process [inference]

glycoside metabolic process [inference]

D-xylulose 5-phosphate metabolic process [inference]

D-glucuronate catabolic process to D-xylulose 5-phosphate

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular detoxification [inference]

cellular detoxification of aldehyde

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

detoxification [inference]

cellular detoxification [inference]

cellular detoxification of aldehyde

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
cytosol	ISS
cytosol	ISO
cytosol	IBA
cytosol	IEA
apical plasma membrane	ISS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane [inference]

plasma membrane region [inference]

apical plasma membrane

cell junction [inference]

synapse

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
aldose reductase (NADPH) activity	ISO
aldose reductase (NADPH) activity	IBA
aldose reductase (NADPH) activity	IEA
all-trans-retinol dehydrogenase (NAD+) activity	ISS
all-trans-retinol dehydrogenase (NAD+) activity	ISO