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Guidelines

MIRAGE

collagen type III alpha 1 chain

Summary

Gene Symbol

Col3a1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

84032

KEGG Gene ID

PubChem

84032

Alliance of Genome Resources

RGD:71029

Annotation

Keyword

Calcium
Collagen
Disulfide bond
Extracellular matrix
Glycoprotein
Hydroxylation
Metal-binding
Reference proteome
Repeat
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P13941
A6INT2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 46 in total

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GO Term	Evidence Code	PMID
skeletal system development	IEP
skeletal system development	IEA
blood vessel development	ISO
in utero embryonic development	ISO
neuron migration	ISO

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

integrin-mediated signaling pathway

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cytokine production [inference]

transforming growth factor beta production [inference]

transforming growth factor beta1 production

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cytokine production [inference]

transforming growth factor beta production [inference]

transforming growth factor beta1 production

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

macromolecule modification [inference]

protein modification process [inference]

peptide cross-linking

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

cell population proliferation [inference]

fibroblast proliferation

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

cell motility [inference]

cell migration [inference]

neuron migration

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

extracellular matrix assembly [inference]

elastic fiber assembly

extracellular structure organization [inference]

extracellular matrix organization

extracellular matrix assembly [inference]

elastic fiber assembly

external encapsulating structure organization [inference]

extracellular matrix organization

extracellular matrix assembly [inference]

elastic fiber assembly

supramolecular fiber organization

elastic fiber assembly

multicellular organismal process [inference]

cytokine production [inference]

transforming growth factor beta production [inference]

transforming growth factor beta1 production

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

multicellular organism growth

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

skeletal system morphogenesis

bone morphogenesis [inference]

endochondral bone morphogenesis

limb joint morphogenesis

tissue morphogenesis [inference]

muscle tissue morphogenesis [inference]

aorta smooth muscle tissue morphogenesis

anatomical structure formation involved in morphogenesis [inference]

layer formation in cerebral cortex

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

system development [inference]

skeletal system development

animal gross anatomical part developmental process [inference]

skeletal system development

blood vessel development

artery development [inference]

aorta development

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

cerebral cortex development

tube development [inference]

digestive tract development

animal organ development [inference]

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

growth [inference]

developmental growth [inference]

multicellular organism growth

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

response to external stimulus [inference]

response to mechanical stimulus

response to abiotic stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to angiotensin

response to chemical [inference]

response to acid chemical [inference]

response to amino acid [inference]

cellular response to amino acid stimulus

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

response to hormone [inference]

response to peptide hormone [inference]

response to angiotensin

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

response to peptide [inference]

response to cytokine

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to angiotensin

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

response to angiotensin

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response

regulation of immune response [inference]

negative regulation of immune response

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

regulation of neuron migration [inference]

negative regulation of neuron migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

negative regulation of cellular process [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

negative regulation of response to stimulus [inference]

negative regulation of immune response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

negative regulation of response to stimulus [inference]

negative regulation of immune response

regulation of immune response [inference]

negative regulation of immune response

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

integrin-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

negative regulation of cellular process [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

regulation of neuron migration [inference]

negative regulation of neuron migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
extracellular region	ISO
collagen trimer	ISO
collagen type III trimer	ISO
collagen type III trimer	IBA
obsolete extracellular space

GO Hierarchy

cellular component

protein-containing complex [inference]

collagen trimer

fibrillar collagen trimer [inference]

collagen type III trimer

extracellular protein-containing complex [inference]

fibrillar collagen trimer [inference]

collagen type III trimer

cellular anatomical structure [inference]

extracellular region

external encapsulating structure [inference]

extracellular matrix

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protease binding	ISO
integrin binding	ISO
extracellular matrix structural constituent	ISO
extracellular matrix structural constituent	IEA
extracellular matrix structural constituent conferring tensile strength	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

extracellular matrix structural constituent conferring tensile strength

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

growth factor binding [inference]

platelet-derived growth factor binding

enzyme binding [inference]

protease binding

SMAD binding

cell adhesion molecule binding [inference]

integrin binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
collagen-containing extracellular matrix	PMID:20610530

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	12825	MGI:88453
Homo sapiens	1281	HGNC:2201

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Last updated: April 6, 2026