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collagen, type III, alpha 1

Summary

Gene Symbol

Col3a1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12825

KEGG Gene ID

PubChem

12825

Alliance of Genome Resources

MGI:88453

Annotation

Keyword

Calcium
Collagen
Disulfide bond
Extracellular matrix
Glycoprotein
Hydroxylation
Metal-binding
Reference proteome
Repeat
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3TVI5
P08121

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 55 in total

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GO Term	Evidence Code	PMID
skeletal system development	IEA
blood vessel development	IMP
in utero embryonic development	IMP
neuron migration	IMP
tissue homeostasis	IMP

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

integrin-mediated signaling pathway

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cytokine production [inference]

transforming growth factor beta production [inference]

transforming growth factor beta1 production

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cytokine production [inference]

transforming growth factor beta production [inference]

transforming growth factor beta1 production

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

macromolecule modification [inference]

protein modification process [inference]

peptide cross-linking

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

cell population proliferation [inference]

fibroblast proliferation

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

cell motility [inference]

cell migration [inference]

neuron migration

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

extracellular matrix assembly [inference]

elastic fiber assembly

extracellular structure organization [inference]

extracellular matrix organization

extracellular matrix assembly [inference]

elastic fiber assembly

external encapsulating structure organization [inference]

extracellular matrix organization

extracellular matrix assembly [inference]

elastic fiber assembly

supramolecular fiber organization

elastic fiber assembly

multicellular organismal process [inference]

cytokine production [inference]

transforming growth factor beta production [inference]

transforming growth factor beta1 production

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

multicellular organism growth

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

skeletal system morphogenesis

bone morphogenesis [inference]

endochondral bone morphogenesis

limb joint morphogenesis

tissue morphogenesis [inference]

muscle tissue morphogenesis [inference]

aorta smooth muscle tissue morphogenesis

anatomical structure formation involved in morphogenesis [inference]

layer formation in cerebral cortex

anatomical structure development [inference]

blood vessel development

artery development [inference]

aorta development

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

cerebral cortex development

tube development [inference]

digestive tract development

animal organ development [inference]

system development [inference]

skeletal system development

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

growth [inference]

developmental growth [inference]

multicellular organism growth

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

response to abiotic stimulus [inference]

response to radiation

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to angiotensin

response to chemical [inference]

response to acid chemical [inference]

response to amino acid [inference]

cellular response to amino acid stimulus

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

response to hormone [inference]

response to peptide hormone [inference]

response to angiotensin

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

response to peptide [inference]

response to cytokine

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to angiotensin

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

response to angiotensin

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response

regulation of immune response [inference]

negative regulation of immune response

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

regulation of neuron migration [inference]

negative regulation of neuron migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

negative regulation of cellular process [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

negative regulation of response to stimulus [inference]

negative regulation of immune response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

negative regulation of response to stimulus [inference]

negative regulation of immune response

regulation of immune response [inference]

negative regulation of immune response

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

integrin-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Rho protein signal transduction

negative regulation of cellular process [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

regulation of neuron migration [inference]

negative regulation of neuron migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of neuron migration

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	IEA
extracellular region	HDA
collagen trimer	IDA
collagen trimer	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

collagen trimer

fibrillar collagen trimer

collagen type III trimer

extracellular protein-containing complex [inference]

fibrillar collagen trimer

collagen type III trimer

cellular anatomical structure [inference]

extracellular region

external encapsulating structure [inference]

extracellular matrix

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
protease binding	ISO
protease binding	IEA
integrin binding	ISO
integrin binding	IEA
extracellular matrix structural constituent	ISO

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

extracellular matrix structural constituent conferring tensile strength

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

growth factor binding [inference]

platelet-derived growth factor binding

enzyme binding [inference]

protease binding

SMAD binding

cell adhesion molecule binding [inference]

integrin binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:14756	vascular type Ehlers-Danlos syndrome	Alliance of Genome Resources
DOID:418	systemic scleroderma	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	84032	RGD:71029
Homo sapiens	1281	HGNC:2201

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

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International Collaboration

Acknowledgements