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solute carrier family 17 member 6

Summary

Gene Symbol

Slc17a6

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

84487

KEGG Gene ID

PubChem

84487

Alliance of Genome Resources

RGD:620531

Annotation

Keyword

3D-structure
Antiport
Cell membrane
Chloride channel
Cytoplasmic vesicle
Glycoprotein
Neurotransmitter transport
Phosphate transport
Reference proteome
Sodium transport
Symport
Synaptosome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JI12	Differentiation-associated BNPI Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter Solute carrier family 17 member 6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
neurotransmitter uptake	ISO
neural retina development	IEP
phosphate ion transport	IDA
L-glutamate transmembrane transport	ISO
L-glutamate transmembrane transport	IDA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

intercellular transport [inference]

neurotransmitter loading into synaptic vesicle

transmembrane transport

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

developmental process [inference]

anatomical structure development [inference]

anatomical structure regression [inference]

hyaloid vascular plexus regression

homeostatic process [inference]

chemical homeostasis [inference]

inorganic ion homeostasis [inference]

phosphate ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

neurotransmitter transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

intercellular transport [inference]

neurotransmitter loading into synaptic vesicle

inorganic anion transport [inference]

phosphate ion transport

sodium-dependent phosphate transport

chloride transport [inference]

chloride transmembrane transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

L-glutamate import

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

L-glutamate import

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

transmembrane transport

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

nitrogen compound transport [inference]

L-amino acid transport [inference]

L-glutamate import

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

import into cell [inference]

neurotransmitter uptake

establishment of localization in cell [inference]

neurotransmitter loading into synaptic vesicle

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

regulation of biological quality [inference]

regulation of synapse structure or activity

Displaying entries **16 - 18** of 18 in total

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GO Term	Evidence Code	PMID
excitatory synapse	IEA
presynapse	ISO
pericellular basket	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

chloride channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

chloride channel complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

cell junction [inference]

synapse

excitatory synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
chloride channel activity	IDA
chloride channel activity	IEA
L-glutamate transmembrane transporter activity	IBA
neurotransmitter transmembrane transporter activity	IBA
sodium:phosphate symporter activity	ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

neurotransmitter transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

metal cation:proton antiporter activity [inference]

potassium:proton antiporter activity

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

potassium:proton antiporter activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity

amino acid transmembrane transporter activity [inference]

acidic amino acid transmembrane transporter activity [inference]

L-glutamate transmembrane transporter activity

L-glutamate uniporter activity

L-amino acid transmembrane transporter activity [inference]

L-glutamate transmembrane transporter activity

L-glutamate uniporter activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

phosphate transmembrane transporter activity [inference]

uniporter activity [inference]

membrane potential driven uniporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

antiporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

potassium:proton antiporter activity

carboxylic acid transmembrane transporter activity [inference]

L-amino acid transmembrane transporter activity [inference]

L-glutamate transmembrane transporter activity

L-glutamate uniporter activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
excitatory synapse	PMID:16519671
early endosome	PMID:11551935
synaptic vesicle	PMID:18502731 PMID:19627441
pericellular basket	PMID:18611437

Ortholog

Displaying **all 9** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	140919	MGI:2156052
Caenorhabditis elegans	176441	WB:WBGene00010755
Caenorhabditis elegans	176291	WB:WBGene00001135
Caenorhabditis elegans	176442	WB:WBGene00011556
Homo sapiens	57084	HGNC:16703
Saccharomyces cerevisiae S288C	850671	SGD:S000003978
Danio rerio	100149756	ZFIN:ZDB-GENE-030616-554
Danio rerio	494492	ZFIN:ZDB-GENE-050105-4
Xenopus tropicalis	780064	Xenbase:XB-GENE-5742677