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slit guidance ligand 2

Summary

Gene Symbol

SLIT2

Organism

Homo sapiens (human)

External Links

NCBI Gene

9353

PubChem

9353

Alliance of Genome Resources

HGNC:11086

Annotation

Keyword

3D-structure
Alternative splicing
Chemotaxis
Developmental protein
Differentiation
Direct protein sequencing
Disulfide bond
EGF-like domain
Glycoprotein
Heparin-binding
Leucine-rich repeat
Neurogenesis
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
O94813

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 46 in total

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GO Term	Evidence Code	PMID
ureteric bud development	IMP	15130495
negative regulation of protein phosphorylation	IDA	18345009
cell migration involved in sprouting angiogenesis	IMP	19351956
negative regulation of leukocyte chemotaxis	IDA	11309622
aortic valve morphogenesis	ISS

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Roundabout signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

apoptotic process involved in development [inference]

apoptotic process involved in luteolysis

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

cellular process involved in reproduction in multicellular organism [inference]

apoptotic process involved in luteolysis

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

endothelial cell migration [inference]

blood vessel endothelial cell migration [inference]

cell migration involved in sprouting angiogenesis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to heparin

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to heparin

cellular response to oxygen-containing compound [inference]

cellular response to heparin

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization [inference]

negative regulation of actin filament polymerization

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

apoptotic process involved in luteolysis

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

regulation of vascular permeability [inference]

negative regulation of vascular permeability

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

heart valve morphogenesis [inference]

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

cardiac septum morphogenesis [inference]

ventricular septum morphogenesis

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

kidney epithelium development [inference]

mesonephric epithelium development [inference]

mesonephric tubule development [inference]

ureteric bud development

tube development [inference]

mesonephric tubule development [inference]

ureteric bud development

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

developmental growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

developmental growth involved in morphogenesis [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

locomotion [inference]

taxis [inference]

chemotaxis [inference]

negative chemotaxis

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to cortisol

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to heparin

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to cortisol

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to heparin

response to heparin [inference]

cellular response to heparin

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to cortisol

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to cortisol

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to heparin

response to alcohol [inference]

response to cortisol

response to ketone [inference]

response to cortisol

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to heparin

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to heparin

cellular response to oxygen-containing compound [inference]

cellular response to heparin

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to heparin

response to heparin [inference]

cellular response to heparin

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to heparin

response to oxygen-containing compound [inference]

response to heparin [inference]

cellular response to heparin

response to alcohol [inference]

response to cortisol

response to ketone [inference]

response to cortisol

cellular response to oxygen-containing compound [inference]

cellular response to heparin

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to heparin

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to heparin

cellular response to oxygen-containing compound [inference]

cellular response to heparin

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

regulation of leukocyte chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

regulation of granulocyte chemotaxis [inference]

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

regulation of neutrophil chemotaxis [inference]

negative regulation of neutrophil chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of neutrophil migration [inference]

regulation of neutrophil chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of cell growth

negative regulation of growth [inference]

negative regulation of cell growth

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of smooth muscle cell chemotaxis

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of smooth muscle cell migration

negative regulation of smooth muscle cell chemotaxis

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of negative chemotaxis [inference]

induction of negative chemotaxis

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

regulation of granulocyte chemotaxis [inference]

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

regulation of neutrophil chemotaxis [inference]

negative regulation of neutrophil chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of negative chemotaxis [inference]

induction of negative chemotaxis

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of smooth muscle cell chemotaxis

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of negative chemotaxis [inference]

positive regulation of negative chemotaxis [inference]

induction of negative chemotaxis

regulation of smooth muscle cell chemotaxis [inference]

negative regulation of smooth muscle cell chemotaxis

regulation of axon guidance [inference]

regulation of retinal ganglion cell axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

regulation of leukocyte chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

regulation of granulocyte chemotaxis [inference]

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

regulation of neutrophil chemotaxis [inference]

negative regulation of neutrophil chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of neutrophil migration [inference]

regulation of neutrophil chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

regulation of smooth muscle cell migration [inference]

negative regulation of smooth muscle cell migration

negative regulation of smooth muscle cell chemotaxis

regulation of smooth muscle cell chemotaxis [inference]

negative regulation of smooth muscle cell chemotaxis

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of smooth muscle cell migration

negative regulation of smooth muscle cell chemotaxis

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of smooth muscle cell migration

negative regulation of smooth muscle cell chemotaxis

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of negative chemotaxis [inference]

induction of negative chemotaxis

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of negative chemotaxis [inference]

induction of negative chemotaxis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

negative regulation of locomotion [inference]

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of smooth muscle cell chemotaxis

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of smooth muscle cell migration

negative regulation of smooth muscle cell chemotaxis

negative regulation of growth [inference]

negative regulation of cell growth

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

negative regulation of cell growth

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of lamellipodium assembly

negative regulation of lamellipodium organization [inference]

negative regulation of lamellipodium assembly

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament polymerization

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of smooth muscle cell migration

negative regulation of smooth muscle cell chemotaxis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

negative regulation of response to external stimulus [inference]

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of smooth muscle cell chemotaxis

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of cellular response to growth factor stimulus

negative regulation of multicellular organismal process [inference]

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of smooth muscle cell chemotaxis

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of negative chemotaxis [inference]

induction of negative chemotaxis

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

regulation of granulocyte chemotaxis [inference]

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

regulation of neutrophil chemotaxis [inference]

negative regulation of neutrophil chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of negative chemotaxis [inference]

induction of negative chemotaxis

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of smooth muscle cell chemotaxis

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of negative chemotaxis [inference]

positive regulation of negative chemotaxis [inference]

induction of negative chemotaxis

regulation of smooth muscle cell chemotaxis [inference]

negative regulation of smooth muscle cell chemotaxis

regulation of axon guidance [inference]

regulation of retinal ganglion cell axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of negative chemotaxis [inference]

induction of negative chemotaxis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

negative regulation of response to external stimulus [inference]

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of smooth muscle cell chemotaxis

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of cellular response to growth factor stimulus

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of cellular response to growth factor stimulus [inference]

negative regulation of cellular response to growth factor stimulus

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

positive regulation of axonogenesis

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Roundabout signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization [inference]

negative regulation of actin filament polymerization

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization [inference]

negative regulation of actin filament polymerization

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

regulation of protein polymerization [inference]

regulation of actin filament polymerization [inference]

negative regulation of actin filament polymerization

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of lamellipodium assembly [inference]

negative regulation of lamellipodium assembly

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of lamellipodium assembly

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction

negative regulation of cell growth

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of lamellipodium assembly

negative regulation of lamellipodium organization [inference]

negative regulation of lamellipodium assembly

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament polymerization

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of smooth muscle cell migration

negative regulation of smooth muscle cell chemotaxis

regulation of cellular component organization [inference]

regulation of cell growth [inference]

negative regulation of cell growth

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of lamellipodium assembly

negative regulation of lamellipodium organization [inference]

negative regulation of lamellipodium assembly

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of lamellipodium assembly [inference]

negative regulation of lamellipodium assembly

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of lamellipodium assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of axonogenesis [inference]

positive regulation of axonogenesis

regulation of axon guidance [inference]

regulation of retinal ganglion cell axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of lamellipodium assembly [inference]

negative regulation of lamellipodium assembly

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of lamellipodium assembly

regulation of lamellipodium organization [inference]

regulation of lamellipodium assembly [inference]

negative regulation of lamellipodium assembly

negative regulation of lamellipodium organization [inference]

negative regulation of lamellipodium assembly

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament polymerization

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization [inference]

negative regulation of actin filament polymerization

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization [inference]

negative regulation of actin filament polymerization

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament polymerization

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

regulation of protein polymerization [inference]

regulation of actin filament polymerization [inference]

negative regulation of actin filament polymerization

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axon guidance [inference]

negative regulation of retinal ganglion cell axon guidance

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of lamellipodium assembly

negative regulation of lamellipodium organization [inference]

negative regulation of lamellipodium assembly

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament polymerization

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

regulation of supramolecular fiber organization [inference]

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization [inference]

negative regulation of actin filament polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament polymerization

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

regulation of leukocyte chemotaxis [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

regulation of granulocyte chemotaxis [inference]

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

regulation of neutrophil chemotaxis [inference]

negative regulation of neutrophil chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of neutrophil migration [inference]

regulation of neutrophil chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

regulation of smooth muscle cell migration [inference]

negative regulation of smooth muscle cell migration

negative regulation of smooth muscle cell chemotaxis

regulation of smooth muscle cell chemotaxis [inference]

negative regulation of smooth muscle cell chemotaxis

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of smooth muscle cell migration

negative regulation of smooth muscle cell chemotaxis

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis

negative regulation of granulocyte chemotaxis [inference]

negative regulation of neutrophil chemotaxis

negative regulation of monocyte chemotaxis

negative regulation of mononuclear cell migration

negative regulation of monocyte chemotaxis

negative regulation of neutrophil migration [inference]

negative regulation of neutrophil chemotaxis

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of smooth muscle cell migration

negative regulation of smooth muscle cell chemotaxis

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of epithelial cell migration [inference]

negative regulation of endothelial cell migration

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of biological quality [inference]

regulation of vascular permeability [inference]

negative regulation of vascular permeability

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization [inference]

negative regulation of actin filament polymerization

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular space	IDA	10102268 16439689 19005219
cytoplasm	IDA	18566128
cell surface	IDA	10102268
membrane	NAS	16439689

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
GTPase inhibitor activity	IDA	16439689 19759280
calcium ion binding	NAS	9813312
protein binding	IPI	10102268 17848514
heparin binding	IDA	17062560
heparin binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

Roundabout binding

identical protein binding

protein homodimerization activity

laminin binding [inference]

laminin-1 binding

proteoglycan binding

protein dimerization activity [inference]

protein homodimerization activity

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

extracellular matrix binding [inference]

laminin binding [inference]

laminin-1 binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

proteoglycan binding

sulfur compound binding [inference]

heparin binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

GTPase inhibitor activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

GTPase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
calcium ion binding

Displaying **all 4** entries
InterPro
EGF-like calcium-binding domain
EGF-like calcium-binding, conserved site
EGF-like domain
EGF-type aspartate/asparagine hydroxylation site

Ortholog

Displaying entries **1 - 10** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	6585	FB:FBgn0264089
Drosophila melanogaster	6586	FB:FBgn0264089
Xenopus tropicalis	9353	Xenbase:XB-GENE-1004410
Drosophila melanogaster	20562	FB:FBgn0264089
Mus musculus	20563	Xenbase:XB-GENE-1004410	MOUSE45542
Drosophila melanogaster	20564	FB:FBgn0264089
Xenopus tropicalis	36746	Xenbase:XB-GENE-1004410
Drosophila melanogaster	65047	FB:FBgn0264089
Danio rerio	80353		DANRE16753
Drosophila melanogaster	83467	FB:FBgn0264089

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

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OrthoDB (Group)

International Collaboration

Acknowledgements