G27798EJ

Summary
GlyTouCan ID
G27798EJ
IUPAC Condensed
Gal(a1-3)Gal(b1-4)GlcNAc(?1-
Motifs
a-Gal antigen
Subsumption Level
Linkage-defined saccharide
Monoisotopic Mass
545.2
GlyGen
ChEBI
PubChem Compound
PubChem Substance
3D Structures
GlycoShape
G27798EJ
Organisms
Taxonomic Hierarchy
KEGG BRITE Database
KEGG ID
Enzyme
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R06145
GlycoEpitope
Epitope ID
EP0200
Epitope Name
Alpha-Galactosyl Epitope
Sequence Descriptors
GlycoCT
RES
1b:x-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-dgal-HEX-1:5
LIN
1:1d(2+1)2n
2:1o(4+1)3d
3:3o(3+1)4d
WURCS
WURCS=2.0/3,3,2/[a2122h-1x_1-5_2*NCC/3=O][a2112h-1b_1-5][a2112h-1a_1-5]/1-2-3/a4-b1_b3-c1
Literature
Displaying entries 1 - 10 of 24 in total
PubMed ID Title First Author Publication Date Source
21168032 Cardiac xenotransplantation technology provides materials for improved bioprosthetic heart valves McGregor CGA 2011 Jan
  • PubChem
21357545 Rapid Recruitment and Activation of Macrophages by Anti-Gal/α-Gal Liposome Interaction Accelerates Wound Healing Wigglesworth KM 2011 Apr 01
  • PubChem
21376382 Impaired allergy diagnostics among parasite-infected patients caused by IgE antibodies to the carbohydrate epitope galactose-α 1,3-galactose Arkestål K 2011 Apr
  • PubChem
21118731 First quantitative assay of alpha-Gal in soft tissues: Presence and distribution of the epitope before and after cell removal from xenogeneic heart valves Naso F 2011 Apr
  • PubChem
21043478 <scp>l</scp>-Rhamnose Antigen: A Promising Alternative to α-Gal for Cancer Immunotherapies Chen W 2010 Nov 11
  • PubChem
19486321 The αGal HyperAcute® Technology: Enhancing Immunogenicity of Antiviral Vaccines by Exploiting the Natural αGal‐Mediated Zoonotic Blockade Mandell RB 2009 Jul 09
  • PubChem
18671678 The Anti-Non-Gal Xenoantibody Response to Xenoantigens on Gal Knockout Pig Cells Is Encoded by a Restricted Number of Germline Progenitors Kiernan K 2008 Sep
  • PubChem
16980056 Distribution of the alpha-gal epitope on adult porcine bone tissue Feng W 2006 Sep
  • GlyGen
  • GlycoEpitope
12009948 Evaluation of different alpha-Galactosyl glycoconjugates for use in xenotransplantation Byrne GW 2002 Mar 26
  • PubChem
11897006 Anti‐pig antibody levels in naïve baboons and cynomolgus monkeys Holmes BJ 2002 Mar
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 10 in total
Title Authors Source Publication Date PubMed ID
Molecular cloning of endo-beta -galactosidase C and its application in removing alpha -galactosyl xenoantigen from blood vessels in the pig kidney.
  • Ogawa H
  • Muramatsu H
  • Kobayashi T
  • Morozumi K
  • Yokoyama I
  • Kurosawa N
  • Nakao A
  • Muramatsu T
J Biol Chem 2000 Jun 23 10858461
Reduction of the major xenoantigen on glycosphingolipids of swine endothelial cells by various glycosyltransferases.
  • Koma M
  • Miyagawa S
  • Honke K
  • Ikeda Y
  • Koyota S
  • Miyoshi S
  • Matsuda H
  • Tsuji S
  • Shirakura R
  • Taniguchi N
Glycobiology 2000 Jul 10910978
Species-specific distribution of alpha-galactosyl epitopes on the gastric H/K ATPase beta-subunit: relevance to the binding of human anti-parietal cell autoantibodies.
  • Stewart LA
  • van Driel IR
  • Toh BH
  • Gleeson PA
Glycobiology 1999 Jun 10336993
Reduction of the major swine xenoantigen, the alpha-galactosyl epitope by transfection of the alpha2,3-sialyltransferase gene.
  • Tanemura M
  • Miyagawa S
  • Koyota S
  • Koma M
  • Matsuda H
  • Tsuji S
  • Shirakura R
  • Taniguchi N
J Biol Chem 1998 Jun 26 9632707
Localization of LewisX, sialyl-LewisX and alpha-galactosyl epitopes on glycosphingolipids in lens tissues.
  • Ogiso M
  • Shogomori H
  • Hoshi M
Glycobiology 1998 Jan 9451018

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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