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G37184KW

Summary

GlyTouCan ID: G37184KW
IUPAC Condensed: Neu5Ac(a2-8)Neu5Ac(a2-3)[Gal(b1-3)GalNAc(b1-4)]Gal(b1-4)Glc(b1-
Motifs: GD1b
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 1289.44

External Links

GlyGen

G37184KW

ChEBI

59222

PubChem Compound

45266846

PubChem Substance

252286914

CarbBank

3D Structures

GLYCAM: Neup5Aca2-8Neup5Aca2-3[DGalpb1-3DGalpNAcb1-4]DGalpb1-4DGlcpb1-OH

GlycoShape

G37184KW

Organisms

Displaying entries **16 - 20** of 37 in total

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Organisms	Evidence
Stenella coeruleoalba (striped dolphin)	GlyTouCan(glycome-db)
Orcinus orca (killer whale)	GlyTouCan(glycome-db)
Trematomus lepidorhinus (slender scalyhead)	GlyTouCan(glycome-db)
Cichlidae (cichlids)	GlyTouCan(glycome-db)
Homo sapiens (human)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Whippomorpha [inference]

Cetacea (whales) [inference]

Mysticeti (baleen whales) [inference]

Balaenopteridae (rorquals) [inference]

Balaenoptera [inference]

Odontoceti (tooth whales) [inference]

Delphinidae (marine dolphins) [inference]

Delphinus [inference]

Delphinus delphis (saddleback dolphin)

Globicephala (pilot whales) [inference]

Globicephala macrorhynchus (short-finned pilot whale)

Stenella [inference]

Stenella coeruleoalba (striped dolphin)

Orcinus [inference]

Orcinus orca (killer whale)

Tursiops [inference]

Tursiops truncatus (common bottlenose dolphin)

Physeteridae (sperm whales) [inference]

Physeter [inference]

Physeter catodon (sperm whale)

Phocoenidae (porpoises) [inference]

Phocoenoides [inference]

Phocoenoides dalli (Dall's porpoise)

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Carnivora (carnivores) [inference]

Feliformia [inference]

Felidae (cat family) [inference]

Felinae [inference]

Felis [inference]

Felis catus (domestic cat)

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Eulipotyphla (hedgehogs, shrews, moles and others) [inference]

Soricidae (shrews)

Crocidurinae [inference]

Suncus (musk shrews) [inference]

Suncus murinus (house shrew)

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Cricetidae [inference]

Cricetinae (hamsters)

Phodopus [inference]

Phodopus sungorus

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Papio (baboons) [inference]

Papio hamadryas (hamadryas baboon)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls) [inference]

Phasianidae (turkeys) [inference]

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Amphibia (amphibians) [inference]

Batrachia [inference]

Anura (frogs and toads) [inference]

Pipoidea [inference]

Pipidae (tongueless frogs) [inference]

Xenopodinae [inference]

Xenopus

Xenopus [inference]

Xenopus laevis (African clawed frog)

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus [inference]

Gadus morhua (Atlantic cod)

Euacanthomorphacea [inference]

Percomorphaceae [inference]

Ovalentaria [inference]

Cichlomorphae [inference]

Cichliformes (cichlids and convict blennies) [inference]

Cichlidae (cichlids)

African cichlids [inference]

Pseudocrenilabrinae [inference]

Oreochromini [inference]

Oreochromis [inference]

Oreochromis mossambicus (Mozambique tilapia)

Eupercaria [inference]

Perciformes (perches and others) [inference]

Notothenioidei [inference]

Nototheniidae (Antarctic cods) [inference]

Trematomus [inference]

Trematomus lepidorhinus (slender scalyhead)

Channichthyidae (crocodile icefishes) [inference]

Chionodraco [inference]

Chionodraco myersi (Myers' icefish)

Otomorpha [inference]

Ostariophysi [inference]

Otophysi [inference]

Cypriniphysae [inference]

Cypriniformes (carps and others) [inference]

Cyprinoidei [inference]

Cyprinidae [inference]

Cyprininae [inference]

Cyprinus [inference]

Cyprinus carpio (common carp)

Carassius [inference]

Carassius auratus (goldfish)

Leuciscidae [inference]

Leuciscinae [inference]

Scardinius [inference]

Scardinius erythrophthalmus (rudd)

Chondrichthyes (cartilaginous fishes) [inference]

Elasmobranchii (elasmobranchs) [inference]

Batoidea (rays) [inference]

Rajiformes (skates) [inference]

Rajidae (hardnose skates) [inference]

Leucoraja [inference]

Leucoraja erinacea (little skate)

Torpediniformes [inference]

Narcinidae (numbfishes) [inference]

Discopyge [inference]

Discopyge tschudii (apron ray)

Torpedinidae (electric rays) [inference]

Torpedo [inference]

Torpedo marmorata (marbled electric ray)

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST8SIA6	CMP-Neu5Ac	G37184KW	Cer	11980897 16120058
ST3GAL6	CMP-Neu5Ac	G37184KW	ceramide	10206952
ST8SIA3	CMP-Neu5Ac	G37184KW	Cer	7782326
B3GALT4	UDP-Gal	G37184KW	Cer	9312075

KEGG BRITE Database

KEGG ID

G00115

Enzyme

References

7553668

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05949	2.4.3.2	G37184KW	G40183QN
R05948	2.4.1.62	G02657AK	G37184KW

GlycoEpitope

Epitope ID: EP0059

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
7b:b-dgal-HEX-1:5
8s:n-acetyl
9b:b-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:3o(8+2)5d
5:5d(5+1)6n
6:2o(4+1)7d
7:7d(2+1)8n
8:7o(3+1)9d

WURCS

WURCS=2.0/4,6,5/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-3-4-2/a4-b1_b3-c2_b4-e1_c8-d2_e3-f1

Literature

Displaying entries **1 - 10** of 28 in total

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PubMed ID	Title	First Author	Publication Date	Source
17855742	Sulfatide binding properties of murine and human antiganglioside antibodies	Townson K	2007 Aug 17	GlyGen GlycoEpitope
16564536	Comprehensive analysis of monoclonal antibodies against detergent-insoluble membrane/lipid rafts of HL60 cells	Yamazaki Y	2006 Apr 20	GlyGen GlycoEpitope
16120058	Molecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteins	Teintenier-Lelièvre M	2005 Dec 06	PubChem
15967512	Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire	Boffey J	2005 Aug	GlyGen GlycoEpitope
15464996	Gangliosides of organ-confined versus metastatic androgen-receptor-negative prostate cancer	Ravindranath MH	2004 Nov 05	GlyGen GlycoEpitope
15223242	Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes	Boffey J	2004 Jul	GlyGen GlycoEpitope
14960498	Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune neuropathy sera	Willison HJ	2003 Nov 07	GlyGen GlycoEpitope
12851687	Expansion of natural killer cells in mice transgenic for IgM antibody to ganglioside GD2: demonstration of prolonged survival after challenge with syngeneic tumor cells	Kawashima I	2003 Aug	GlyGen GlycoEpitope
11878808	Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides	Schnaar RL	2002 Mar 15	GlyGen GlycoEpitope
11980897	Molecular cloning and expression of a sixth type of alpha 2,8-sialyltransferase (ST8Sia VI) that sialylates O-glycans	Takashima S	2002 Jul 05	PubChem

PubAnnotation

Displaying entries **1 - 5** of 10 in total

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Title	Authors	Source	Publication Date	PubMed ID
Attenuation of interleukin 2 signal in the spleen cells of complex ganglioside-lacking mice.	Zhao J Furukawa K Fukumoto S Okada M Furugen R Miyazaki H Takamiya K Aizawa S Shiku H Matsuyama T Furukawa K	J Biol Chem	1999 May 14	10318776
Activation of human T lymphocytes by ganglioside-containing liposomes.	Yanagihara K Kato E Hitomi S Sunamoto J Wada H	Glycoconj J	1999 Jan	10580651
Synthesis of a photoreactive, radiolabelled derivative of the oligosaccharide of GM1 ganglioside.	Pacuszka T Fishman PH	Glycobiology	1992 Jun	1498422
Generation of one set of monoclonal antibodies specific for b-pathway ganglio-series gangliosides.	Ozawa H Kotani M Kawashima I Tai T	Biochim Biophys Acta	1992 Jan 24	1371229
Ganglioside-binding proteins in skeletal and cardiac muscle.	Chan KF Liu Y	Glycobiology	1991 Mar	1823162

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements