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GlyTouCan
Glycan Structure Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B3GALT1 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALNT3 | UDP-GalNAc |
G49108TO
|
R |
G00057MO
|
R | |
| B3GALNT2 | UDP-GalNAc |
G49108TO
|
R |
G36387CV
|
R | |
| B4GALNT4 | UDP-GalNAc |
G49108TO
|
R |
G00057MO
|
R | |
| B4GALT1 | UDP-Glc |
G49108TO
|
R |
G38884XS
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| O75044 | SLIT-ROBO Rho GTPase-activating protein 2 | ||
| O75071 | EF-hand calcium-binding domain-containing protein 14 | ||
| O75094 | Slit homolog 3 protein | ||
| O75096 | Low-density lipoprotein receptor-related protein 4 | ||
| O75113 | NEDD4-binding protein 1 | ||
| O75116 | Rho-associated protein kinase 2 | ||
| O75122 | CLIP-associating protein 2 | ||
| O75131 | Copine-3 | ||
| O75132 | Zinc finger BED domain-containing protein 4 | ||
| O75140 | GATOR1 complex protein DEPDC5 |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Antimicrobial peptides | Drosophila melanogaster |
| Antimicrobial peptides | Rattus norvegicus |
| Antimicrobial peptides | Danio rerio |
| Antimicrobial peptides | Xenopus tropicalis |
| Antimicrobial peptides | Gallus gallus |
| Antimicrobial peptides | Homo sapiens |
| Antimicrobial peptides | Canis familiaris |
| Antimicrobial peptides | Dictyostelium discoideum |
| Antimicrobial peptides | Bos taurus |
| Antimicrobial peptides | Mus musculus |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 36124412 | Hexosamine pathway activation improves memory but does not extend lifespan in mice | Allmeroth K | 2022 Sep 19 |
|
| 36115831 | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation | Jiang J | 2022 Sep 17 |
|
| 35971553 | Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways | Zhao F | 2022 Sep 16 |
|
| 36103542 | Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response | Dickey TH | 2022 Sep 16 |
|
| 36109732 | A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode | Zhao D | 2022 Sep 15 |
|
| 36106687 | Crystal structure and sugar-binding ability of the C-terminal domain of N-acetylglucosaminyltransferase IV establish a new carbohydrate-binding module family | Oka N | 2022 Sep 15 |
|
| 36104594 | The value of injectable viscoelastic supplements for joints | Bowden DJ | 2022 Sep 14 |
|
| 36104770 | O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy | Lu Q | 2022 Sep 14 |
|
| 35977542 | Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses | McLeod B | 2022 Sep 13 |
|
| 35952670 | Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus | Sangesland M | 2022 Sep 13 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation. |
|
J Am Chem Soc | 2003 Jun 4 | 12769553 |
| Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line. |
|
Biochim Biophys Acta | 1999 Oct 18 | 10572927 |
| Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. |
|
J Biol Chem | 1999 Nov 5 | 10542233 |
| An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro. |
|
J Biol Chem | 1999 May 21 | 10329728 |
| Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine. |
|
J Biol Chem | 1992 Jan 5 | 1730617 |
