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G49108TO

Summary

GlyTouCan ID: G49108TO
IUPAC Condensed: GlcNAc(b1-

External Links

GlyConnect structure

8849

GlyGen

G49108TO

ChEBI

28009

PubChem Compound

24139

PubChem Substance

252288111

The Human Metabolome Database

HMDB0000803

3D Structures

GLYCAM: DGlcpNAcb1-OH

GlycoShape

G49108TO

Displaying 1 entry
Archetype	α	β
G14843DJ	G68544GH	G49108TO

Organisms

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Organisms	Evidence
Mus musculus (house mouse)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Rattus norvegicus (Norway rat)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Homo sapiens (human)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlyTouCan(glycome-db) GlycoEpitope
Drosophila melanogaster (fruit fly)	GlyGen(OGlcNAcDB)
Streptococcus pneumoniae	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Negarnaviricota [inference]

Polyploviricotina [inference]

Insthoviricetes [inference]

Articulavirales [inference]

Orthomyxoviridae [inference]

unclassified Orthomyxoviridae [inference]

unidentified influenza virus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT2	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT1	UDP-Gal	G49108TO	R	G00055MO	R	3014508
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B4GALT3	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT4	UDP-Gal	G49108TO	[beta]-1-Benzl	G00055MO	[beta]-1-Benzl	9792633
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT4	UDP-Gal	G49108TO	[beta]-1-4-methyl-umbelliferyl	G00055MO	[beta]-1-4-methyl-umbelliferyl	9792633

Displaying entries **16 - 20** of 24 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
B3GNT2	UDP-GalNAc	G49108TO	[beta]1-OBn	9892646
B3GLCT	UDP-Glc	G49108TO	[beta]-benzyl	16899492
B3GNT6	UDP-GlcNAc	G49108TO	[beta]-pNP	11821425
B3GNT7	UDP-GlcNAc	G49108TO	[beta]-Bz	15620693
MGAT5	UDP-GlcNAc	G49108TO		19846580

KEGG BRITE Database

KEGG ID

Enzyme

2.4.1.255

Core Protein

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UniProt ID	Protein Name	Reference	Source
A0A061AE78	DMAP1-binding domain-containing protein	31682414	The O-GlcNAc Database
A0A087WXM9	Meiosis-specific kinetochore protein	30379171	GlyGen The O-GlcNAc Database
A0A087X1C1	Thymosin beta 15C	31492838	The O-GlcNAc Database
A0A0A6YVU8	Adhesion regulating molecule 1B	30059200 37507081	GlyGen The O-GlcNAc Database
A0A0B4J1U4	T cell receptor gamma variable 5	38253038	The O-GlcNAc Database
A0A0B4J1W7	Nuclear pore complex-interacting protein family member A9	39531497	The O-GlcNAc Database
A0A0B4J203	receptor protein-tyrosine kinase	28510447 30620550 31492838 35254053	The O-GlcNAc Database
A0A0B4J2E0	T cell receptor beta variable 12-4	38253038	The O-GlcNAc Database
A0A0C4DFX4	Snf2 related CREBBP activator protein (Fragment)	30620550 31492838 35254053	The O-GlcNAc Database
A0A0C4DH32	Immunoglobulin heavy variable 3-20	38253038	The O-GlcNAc Database

GlycoEpitope

Epitope ID: EP0004

Pathway

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Pathway Name	Organism
E.coli O152	Escherichia coli
E.coli O156	Escherichia coli
E.coli O158ac	Escherichia coli
E.coli O159	Escherichia coli
E.coli O160	Escherichia coli
E.coli O161	Escherichia coli
E.coli O167	Escherichia coli
E.coli O168	Escherichia coli
E.coli O16H48K12	Escherichia coli
E.coli O170	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/

Literature

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PubMed ID	Title	First Author	Publication Date	Source
35325595	Facile discovery of surrogate cytokine agonists	Yen M	2022 Apr 14	PubChem
35344711	Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody	Li C	2022 Apr 14	PubChem
35422493	O-GlcNAcylation and stablization of SIRT7 promote pancreatic cancer progression by blocking the SIRT7-REGgamma interaction	He X	2022 Apr 14	GlyGen PubChem
35420322	Molecular docking unveils the potential of andrographolide derivatives against COVID-19: an in silico approach	Veerasamy R	2022 Apr 14	PubChem
35247328	Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases	Chang A	2022 Apr 14	PubChem
35419655	Simulations suggest double sodium binding induces unexpected conformational changes in thrombin	Wu D	2022 Apr 13	PubChem
35385697	Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C	Zhao M	2022 Apr 12	GlyGen PubChem
35414690	The intra-mitochondrial O-GlcNAcylation system rapidly modulates OXPHOS function and ROS release in the heart	Dontaine J	2022 Apr 12	PubChem
35479087	Inhibition of O-GlcNAcylation Decreases the Cytotoxic Function of Natural Killer Cells	Feinberg D	2022 Apr 11	PubChem
35394827	Cryo-EM structures of the human surfactant lipid transporter ABCA3	Xie T	2022 Apr 08	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation.	Lamarre-Vincent N Hsieh-Wilson LC	J Am Chem Soc	2003 Jun 4	12769553
Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line.	Lefebvre T Alonso C Mahboub S Dupire MJ Zanetta JP Caillet-Boudin ML Michalski JC	Biochim Biophys Acta	1999 Oct 18	10572927
Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats.	Kreppel LK Hart GW	J Biol Chem	1999 Nov 5	10542233
An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro.	Su K Roos MD Yang X Han I Paterson AJ Kudlow JE	J Biol Chem	1999 May 21	10329728
Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine.	Roquemore EP Dell A Morris HR Panico M Reason AJ Savoy LA Wistow GJ Zigler JS Jr Earles BJ Hart GW	J Biol Chem	1992 Jan 5	1730617

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements