GlyCosmos Portal

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3D Structures

GLYCAM: DGlcpNAcb1-OH

GlycoShape

G49108TO

Displaying 1 entry
Archetype	α	β
G14843DJ	G68544GH	G49108TO

Organisms

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Organisms	Evidence
Streptococcus pneumoniae	GlyTouCan(bcsdb)
Mus musculus (house mouse)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Saccharomyces cerevisiae (brewer's yeast)	GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB)
Sus scrofa (pig)	GlyGen(OGlcNAcAtlas)
Rattus norvegicus (Norway rat)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Negarnaviricota [inference]

Polyploviricotina [inference]

Insthoviricetes [inference]

Articulavirales [inference]

Orthomyxoviridae [inference]

unclassified Orthomyxoviridae [inference]

unidentified influenza virus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B4GALT1	UDP-Gal	G49108TO	R	G00055MO	R	3014508
B4GALT2	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B4GALT4	UDP-Gal	G49108TO	[beta]-1-thio-p-Nitrophenyl	G00055MO	[beta]-1-thio-p-Nitrophenyl	9792633
B4GALT3	UDP-Gal	G49108TO	4-Me-lumbelyl-[beta]	G00055MO	4-Me-lumbelyl-[beta]	9405390
B4GALT4	UDP-Gal	G49108TO	[beta]-1-4-methyl-umbelliferyl	G00055MO	[beta]-1-4-methyl-umbelliferyl	9792633
B4GALT1	UDP-Gal	G49108TO		G00055MO		10580128

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
B3GALNT2	UDP-GalNAc	G49108TO	[alpha]-Bz	14724282
B3GLCT	UDP-Glc	G49108TO	[beta]-benzyl	16899492
B3GNT2	UDP-GlcNAc	G49108TO	[beta]1-OBn	9892646
MGAT5	UDP-GlcNAc	G49108TO		19846580
B3GNT8	UDP-GlcNAc	G49108TO	[alpha]-Bz	15620693

KEGG BRITE Database

KEGG ID

Enzyme

2.4.1.255

Core Protein

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UniProt ID	Protein Name	Reference	Source
Q9UPU5	Ubiquitin carboxyl-terminal hydrolase 24	23301498 28510447 38253038	The O-GlcNAc Database
Q9UPV9	Trafficking kinesin-binding protein 1	12724313 24995978 28657654 30620550 34019948 39302247	GlyGen The O-GlcNAc Database
Q9UPW6	DNA-binding protein SATB2	30379171 39531497	GlyGen The O-GlcNAc Database
Q9UPX0	Protein turtle homolog B	28411811 38253038	The O-GlcNAc Database
Q9UPX8	SH3 and multiple ankyrin repeat domains protein 2	28657654 30620550 35132862 37340703 38665916 39531497	The O-GlcNAc Database
Q9UPY5	Cystine/glutamate transporter	28411811 34725712 37867237	The O-GlcNAc Database
Q9UPZ3	BLOC-2 complex member HPS5	23301498 39531497	The O-GlcNAc Database
Q9UQ26	Regulating synaptic membrane exocytosis protein 2	28657654 37217939	GlyGen The O-GlcNAc Database
Q9UQ35	Serine/arginine repetitive matrix protein 2	20068230 23301498 26853435 27655845 28657654 29237092 29351928 30059200 30379171 30620550 31373491 31492838 32119511 32574038 33214551 34019948 34229054 34725712 34846842 35132862 35138101 35254053 35289036 36580660 37217939 37340703 38253038 38665916 39302247 39531497 39534244	GlyGen The O-GlcNAc Database GlyConnect
Q9UQ52	Contactin-6	38253038	The O-GlcNAc Database

GlycoEpitope

Epitope ID: EP0004

Pathway

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Pathway Name	Organism
Antimicrobial peptides	Sus scrofa
Antimicrobial peptides	Rattus norvegicus
Antimicrobial peptides	Dictyostelium discoideum
Antimicrobial peptides	Bos taurus
Antimicrobial peptides	Canis familiaris
Antimicrobial peptides	Mus musculus
Antimicrobial peptides	Gallus gallus
Antimicrobial peptides	Homo sapiens
Antimicrobial peptides	Drosophila melanogaster
Antimicrobial peptides	Xenopus tropicalis

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/

Literature

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PubMed ID	Title	First Author	Publication Date	Source
35881786	Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo	de Boer C	2022 Jul 26	PubChem
35879403	SIRT1 deficiency increases O-GlcNAcylation of tau, mediating synaptic tauopathy	Yin X	2022 Jul 25	GlyGen PubChem
35879546	O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1	Zhu Q	2022 Jul 25	GlyGen PubChem
35879526	Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys	Fenwick C	2022 Jul 25	PubChem
35875870	Discovery of a Transferrin Receptor 1-Binding Aptamer and Its Application in Cancer Cell Depletion for Adoptive T-Cell Therapy Manufacturing	Cheng EL	2022 Jul 24	PubChem
35897896	Mechano-Enzymatic Degradation of the Chitin from Crustacea Shells for Efficient Production of N-acetylglucosamine (GlcNAc)	Yu X	2022 Jul 23	PubChem
35867186	Constitutive chitosanase from Bacillus thuringiensis B-387 and its potential for preparation of antimicrobial chitooligomers	Aktuganov GE	2022 Jul 22	PubChem
35937804	NAT10 Maintains OGA mRNA Stability Through ac4C Modification in Regulating Oocyte Maturation	Lin J	2022 Jul 22	PubChem
35935935	Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity	Pedersen H	2022 Jul 22	PubChem
35762884	Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution	Starr TN	2022 Jul 22	PubChem

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements