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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Lectin pathway of complement activation | Mus musculus |
| Lectin pathway of complement activation | Bos taurus |
| Lectin pathway of complement activation | Rattus norvegicus |
| Lectin pathway of complement activation | Xenopus tropicalis |
| Lectin pathway of complement activation | Gallus gallus |
| Lectin pathway of complement activation | Homo sapiens |
| Lectin pathway of complement activation | Canis familiaris |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 39446989 | The Discovery of MORF-627, a Highly Selective Conformationally-Biased Zwitterionic Integrin αvβ6 Inhibitor for Fibrosis | Harrison BA | 2024 Oct 24 |
|
| 39441630 | Cryo-EM structure of the zinc-activated channel (ZAC) in the Cys-loop receptor superfamily | Jin F | 2024 Oct 23 |
|
| 39442557 | Molecular mechanism of IgE-mediated FcεRI activation | Chen M | 2024 Oct 23 |
|
| 38464151 | Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination | Clark JJ | 2024 Oct 23 |
|
| 39422475 | On the humanization of VHHs: Prospective case studies, experimental and computational characterization of structural determinants for functionality | Fernández-Quintero ML | 2024 Oct 18 |
|
| 39425013 | New perspectives on YTHDF2 O-GlcNAc modification in the pathogenesis of intervertebral disc degeneration | Lu L | 2024 Oct 18 |
|
| 39464000 | Initiation of ERAD by the bifunctional complex of Mnl1 mannosidase and protein disulfide isomerase | Zhao D | 2024 Oct 17 |
|
| 39413067 | The correlation between cellular O-GlcNAcylation and sensitivity to O-GlcNAc inhibitor in colorectal cancer cells | Wongprayoon P | 2024 Oct 16 |
|
| 39407062 | Modulation of Plet1 expression by N-Acetylglucosamine through the IL-17 A-MAPK pathway in an imiquimod-induced psoriasis mouse model | Selvakumar B | 2024 Oct 15 |
|
| 39405070 | O-GlcNAc participates in the meiosis of aging oocytes by mediating mitochondrial function | Li C | 2024 Oct 15 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Phosphorylation activates master growth regulator DELLA by promoting histone H2A binding at chromatin in Arabidopsis. |
|
Nat Commun | 2024 Sep 3 | 39227587 |
| A protein O-GlcNAc glycosyltransferase regulates the antioxidative response in Yersinia pestis. |
|
Nat Commun | 2024 Aug 16 | 39152136 |
| Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis. |
|
Nat Commun | 2017 Dec 5 | 29208956 |
| Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation. |
|
J Biol Chem | 2016 Jun 17 | 27129262 |
| The making of a sweet modification: structure and function of O-GlcNAc transferase. |
|
J Biol Chem | 2014 Dec 12 | 25336649 |
