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Glycan Structure Repository
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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT1 | UDP-Gal |
G49108TO
|
G00055MO
|
|||
| B4GALT4 | UDP-Gal |
G49108TO
|
G00055MO
|
|||
| B4GALT3 | UDP-Gal |
G49108TO
|
4-Me-lumbelyl-[beta] |
G00055MO
|
4-Me-lumbelyl-[beta] | |
| B4GALT2 | UDP-Gal |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
p-Nitrophenyl-1-thio-[beta] |
G00055MO
|
p-Nitrophenyl-1-thio-[beta] |
Core Protein
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Antimicrobial peptides | Drosophila melanogaster |
| Antimicrobial peptides | Rattus norvegicus |
| Antimicrobial peptides | Danio rerio |
| Antimicrobial peptides | Xenopus tropicalis |
| Antimicrobial peptides | Gallus gallus |
| Antimicrobial peptides | Homo sapiens |
| Antimicrobial peptides | Canis familiaris |
| Antimicrobial peptides | Dictyostelium discoideum |
| Antimicrobial peptides | Bos taurus |
| Antimicrobial peptides | Mus musculus |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 34978456 | Total Chemical Synthesis of Correctly Folded Disulfide-Rich Proteins Using a Removable O-Linked β-N-Acetylglucosamine Strategy | Shi WW | 2022 Jan 03 |
|
| 34922944 | Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2 | Nakanishi H | 2022 Jan |
|
| 34861239 | The active site region plays a critical role in Na+ binding to thrombin | Pelc LA | 2022 Jan |
|
| 34126155 | Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response | Atanasio A | 2022 Jan |
|
| 34981577 | O ‐GlcNAcylation regulates β1,4‐GlcNAc‐branched N ‐glycan biosynthesis via the OGT/SLC35A3/GnT‐IV axis | Song W | 2022 Feb |
|
| 35076256 | Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement | McCallum M | 2022 Feb 25 |
|
| 35217634 | Structure and assembly of the S-layer in C. difficile | Lanzoni-Mangutchi P | 2022 Feb 25 |
|
| 35192429 | Improved therapeutic index of an acidic pH-selective antibody | Lee PS | 2022 Feb 22 |
|
| 35190631 | Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells | Shimizu M | 2022 Feb 21 |
|
| 35050643 | SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein–ACE2 complex | Mannar D | 2022 Feb 18 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Blocking O-linked GlcNAc cycling in Drosophila insulin-producing cells perturbs glucose-insulin homeostasis. |
|
J Biol Chem | 2010 Dec 3 | 20926386 |
| Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase. |
|
J Biol Chem | 2002 Jan 18 | 11788610 |
| Increased N-acetyl-beta-glucosaminidase activity in primary breast carcinomas corresponds to a decrease in N-acetylglucosamine containing proteins. |
|
Biochim Biophys Acta | 2001 Sep 28 | 11566258 |
| Clathrin assembly protein AP-3 is phosphorylated and glycosylated on the 50-kDa structural domain. |
|
J Biol Chem | 1994 Aug 19 | 8063760 |
