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G49108TO

Summary

GlyTouCan ID: G49108TO
IUPAC Condensed: GlcNAc(b1-

External Links

GlyConnect structure

8849

GlyGen

G49108TO

ChEBI

28009

PubChem Compound

24139

PubChem Substance

252288111

The Human Metabolome Database

HMDB0000803

3D Structures

GLYCAM: DGlcpNAcb1-OH

GlycoShape

G49108TO

Displaying 1 entry
Archetype	α	β
G14843DJ	G68544GH	G49108TO

Organisms

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Organisms	Evidence
Mus musculus (house mouse)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Rattus norvegicus (Norway rat)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Homo sapiens (human)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlyTouCan(glycome-db) GlycoEpitope
Drosophila melanogaster (fruit fly)	GlyGen(OGlcNAcDB)
Streptococcus pneumoniae	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Negarnaviricota [inference]

Polyploviricotina [inference]

Insthoviricetes [inference]

Articulavirales [inference]

Orthomyxoviridae [inference]

unclassified Orthomyxoviridae [inference]

unidentified influenza virus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT2	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT1	UDP-Gal	G49108TO	R	G00055MO	R	3014508
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226
B3GALT1	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT4	UDP-Gal	G49108TO	[beta]-1-thio-p-Nitrophenyl	G00055MO	[beta]-1-thio-p-Nitrophenyl	9792633
B4GALNT3	UDP-GalNAc	G49108TO	R	G00057MO	R	12966086
B3GALNT2	UDP-GalNAc	G49108TO	[beta]-Bz	G36387CV	[beta]-Bz	14724282

Displaying entries **1 - 5** of 24 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL2	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G49108TO	benzyl	11062056
ST6GAL1	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
CHST7	PAPS	G49108TO	-O-CH3	10781596
CHST3	PAPS	G49108TO	-O-CH3	10781596

KEGG BRITE Database

KEGG ID

Enzyme

2.4.1.255

Core Protein

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UniProt ID	Protein Name	Reference	Source
A0A061AE78	DMAP1-binding domain-containing protein	31682414	The O-GlcNAc Database
A0A087WXM9	Meiosis-specific kinetochore protein	30379171	GlyGen The O-GlcNAc Database
A0A087X1C1	Thymosin beta 15C	31492838	The O-GlcNAc Database
A0A0A6YVU8	Adhesion regulating molecule 1B	30059200 37507081	GlyGen The O-GlcNAc Database
A0A0B4J1U4	T cell receptor gamma variable 5	38253038	The O-GlcNAc Database
A0A0B4J1W7	Nuclear pore complex-interacting protein family member A9	39531497	The O-GlcNAc Database
A0A0B4J203	receptor protein-tyrosine kinase	28510447 30620550 31492838 35254053	The O-GlcNAc Database
A0A0B4J2E0	T cell receptor beta variable 12-4	38253038	The O-GlcNAc Database
A0A0C4DFX4	Snf2 related CREBBP activator protein (Fragment)	30620550 31492838 35254053	The O-GlcNAc Database
A0A0C4DH32	Immunoglobulin heavy variable 3-20	38253038	The O-GlcNAc Database

GlycoEpitope

Epitope ID: EP0004

Pathway

Displaying entries **11 - 20** of **127** in total

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Pathway Name	Organism
Antimicrobial peptides	Rattus norvegicus
E.coli O10	Escherichia coli
E.coli O103	Escherichia coli
E.coli O105	Escherichia coli
E.coli O109	Escherichia coli
E.coli O110	Escherichia coli
E.coli O111	Escherichia coli
E.coli O112ab	Escherichia coli
E.coli O113	Escherichia coli
E.coli O115	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/

Literature

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PubMed ID	Title	First Author	Publication Date	Source
35256819	An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy	Chan S	2022 Mar 07	PubChem
35253643	How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition	Goodman KM	2022 Mar 07	PubChem
35253970	Biparatopic sybodies neutralize SARS‐CoV‐2 variants of concern and mitigate drug resistance	Walter JD	2022 Mar 07	PubChem
35246509	Evolution of the SARS-CoV-2 spike protein in the human host	Wrobel AG	2022 Mar 04	PubChem
35133176	Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody	Yin W	2022 Mar 04	PubChem
35120603	Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron	Cui Z	2022 Mar 03	PubChem
35241675	Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain	Ye G	2022 Mar 03	PubChem
35236939	Structural basis of the activation of metabotropic glutamate receptor 3	Fang W	2022 Mar 02	PubChem
35172173	Cryo-EM structure of the SARS-CoV-2 Omicron spike	Cerutti G	2022 Mar 01	PubChem
35230385	Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller	Lorin V	2022 Mar 01	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation.	Lamarre-Vincent N Hsieh-Wilson LC	J Am Chem Soc	2003 Jun 4	12769553
Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line.	Lefebvre T Alonso C Mahboub S Dupire MJ Zanetta JP Caillet-Boudin ML Michalski JC	Biochim Biophys Acta	1999 Oct 18	10572927
Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats.	Kreppel LK Hart GW	J Biol Chem	1999 Nov 5	10542233
An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro.	Su K Roos MD Yang X Han I Paterson AJ Kudlow JE	J Biol Chem	1999 May 21	10329728
Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine.	Roquemore EP Dell A Morris HR Panico M Reason AJ Savoy LA Wistow GJ Zigler JS Jr Earles BJ Hart GW	J Biol Chem	1992 Jan 5	1730617

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements