GlyCosmos Portal

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3D Structures

GLYCAM: DGlcpNAcb1-OH

GlycoShape

G49108TO

Displaying 1 entry
Archetype	α	β
G14843DJ	G68544GH	G49108TO

Organisms

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Organisms	Evidence
Streptococcus pneumoniae	GlyTouCan(bcsdb)
Mus musculus (house mouse)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Saccharomyces cerevisiae (brewer's yeast)	GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB)
Sus scrofa (pig)	GlyGen(OGlcNAcAtlas)
Rattus norvegicus (Norway rat)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Negarnaviricota [inference]

Polyploviricotina [inference]

Insthoviricetes [inference]

Articulavirales [inference]

Orthomyxoviridae [inference]

unclassified Orthomyxoviridae [inference]

unidentified influenza virus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B4GALT1	UDP-Gal	G49108TO	R	G00055MO	R	3014508
B4GALT2	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226
B4GALT4	UDP-Gal	G49108TO		G00055MO		10580128
B3GALT1	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALNT4	UDP-GalNAc	G49108TO	R	G00057MO	R	15044014
B4GALNT3	UDP-GalNAc	G49108TO	R	G00057MO	R	12966086

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL1	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
ST6GAL2	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G49108TO	benzyl	11062056
CHST7	PAPS	G49108TO	-O-CH3	10781596
CHST3	PAPS	G49108TO	-O-CH3	10781596

KEGG BRITE Database

KEGG ID

Enzyme

2.4.1.255

Core Protein

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UniProt ID	Protein Name	Reference	Source
Q9Y2R4	Probable ATP-dependent RNA helicase DDX52	32522876 34019948 35132862 38665916	GlyGen The O-GlcNAc Database
Q9Y2T7	Y-box-binding protein 2	22121020 34019948 37217939 38253038	The O-GlcNAc Database
Q9Y2U8	Inner nuclear membrane protein Man1	30379171 34019948 35254053 38665916	GlyGen The O-GlcNAc Database
Q9Y2V7	Conserved oligomeric Golgi complex subunit 6	38253038	The O-GlcNAc Database
Q9Y2W1	Thyroid hormone receptor-associated protein 3	29351928 30379171 32119511 32522876 33214551 33465208 34019948 34229054 35254053 36580660 37217939 38665916	GlyGen The O-GlcNAc Database
Q9Y2W2	WW domain-binding protein 11	28510447 30444036 33214551 34019948 35254053 37217939	GlyGen The O-GlcNAc Database
Q9Y2X0	Mediator of RNA polymerase II transcription subunit 16	30379171 34019948	GlyGen The O-GlcNAc Database
Q9Y2X3	Nucleolar protein 58	23301498 27655845 28510447 28760965 30620550 32119511 32522876 33214551 34019948 34229054 34725712 34931806 35083852 35132862 35138101 37217939 38665916	GlyGen The O-GlcNAc Database
Q9Y2X7	ARF GTPase-activating protein GIT1	28657654 34019948 35132862	GlyGen The O-GlcNAc Database
Q9Y2X9	Zinc finger protein 281	20068230 23301498 26280087 29351928 30059200 30620550 31492838 32574038 33214551 34019948 34725712 35132862 35138101 35254053 35289036 37340703 38665916 39302247 39531497 39534244	GlyGen The O-GlcNAc Database GlyConnect

GlycoEpitope

Epitope ID: EP0004

Pathway

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Pathway Name	Organism
Antimicrobial peptides	Sus scrofa
Antimicrobial peptides	Rattus norvegicus
Antimicrobial peptides	Dictyostelium discoideum
Antimicrobial peptides	Bos taurus
Antimicrobial peptides	Canis familiaris
Antimicrobial peptides	Mus musculus
Antimicrobial peptides	Gallus gallus
Antimicrobial peptides	Homo sapiens
Antimicrobial peptides	Drosophila melanogaster
Antimicrobial peptides	Xenopus tropicalis

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/

Literature

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PubMed ID	Title	First Author	Publication Date	Source
36593962	Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment	Wang R	2023	PubChem
36255673	Synthesis of O-Linked Glycoconjugates in the Nervous System	Inokuchi JI	2023	PubChem
36255678	Brain O-GlcNAcylation: From Molecular Mechanisms to Clinical Phenotype	Uygar B	2023	PubChem
36662460	Proteoglycans: A Tool for Detecting Hyaluronan by ELISA-Like Methods	Vitale DL	2023	PubChem
36512248	Identification and Characterization of GRASP55 O-GlcNAcylation	Zhang X	2023	PubChem
36288343	First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy	Zhu WZ	2022	GlyGen PubChem
35604954	Disaccharide-tag for highly sensitive identification of O-GlcNAc-modified proteins in mammalian cells	Abo H	2022	GlyGen PubChem
35308201	SLC35B4 Stabilizes c-MYC Protein by O-GlcNAcylation in HCC	Jiang T	2022	GlyGen PubChem
36032089	Penta-o-galloyl-beta-d-Glucose (PGG) inhibits inflammation in human rheumatoid arthritis synovial fibroblasts and rat adjuvant-induced arthritis model	Umar S	2022	GlyGen PubChem
35432339	Chronically Elevated O-GlcNAcylation Limits Nitric Oxide Production and Deregulates Specific Pro-Inflammatory Cytokines	Abramowitz LK	2022	GlyGen PubChem

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements