G49108TO
| Organisms | Evidence | 
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference | 
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) | 
                          
                             | 
                    [beta]-S-pNP | 
                          
                             | 
                    [beta]-S-pNP | |
| B3GALT2 | UDP-Gal | 
                          
                             | 
                    Lemieux | 
                          
                             | 
                    Lemieux | |
| B4GALT2 | UDP-Gal | 
                          
                             | 
                    Benzyl-[beta] | 
                          
                             | 
                    Benzyl-[beta] | |
| B4GALT1 | UDP-Gal | 
                          
                             | 
                    R | 
                          
                             | 
                    R | |
| B3GALT5 | UDP-Gal | 
                          
                             | 
                    R | 
                          
                             | 
                    R | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference | 
|---|---|---|---|---|---|---|
| B4GALNT4 | UDP-GalNAc | 
                          
                             | 
                    [beta]-Bz | 
                          
                             | 
                    [beta]-Bz | |
| B4GALNT3 | UDP-GalNAc | 
                          
                             | 
                    [beta]-Bz | 
                          
                             | 
                    [beta]-Bz | |
| B3GALNT2 | UDP-GalNAc | 
                          
                             | 
                    R | 
                          
                             | 
                    R | |
| B4GALNT4 | UDP-GalNAc | 
                          
                             | 
                    R | 
                          
                             | 
                    R | |
| B4GALT1 | UDP-Glc | 
                          
                             | 
                    R | 
                          
                             | 
                    R | 
| Pathway Name | Organism | 
|---|---|
| Antimicrobial peptides | Xenopus tropicalis | 
| Antimicrobial peptides | Rattus norvegicus | 
| Antimicrobial peptides | Danio rerio | 
| Antimicrobial peptides | Bos taurus | 
| Antimicrobial peptides | Canis familiaris | 
| Antimicrobial peptides | Sus scrofa | 
| Antimicrobial peptides | Dictyostelium discoideum | 
| Antimicrobial peptides | Mus musculus | 
| Antimicrobial peptides | Drosophila melanogaster | 
| Antimicrobial peptides | Homo sapiens | 
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
| PubMed ID | Title | First Author | Publication Date | Source | 
|---|---|---|---|---|
| 36124412 | Hexosamine pathway activation improves memory but does not extend lifespan in mice | Allmeroth K | 2022 Sep 19 | 
                  
  | 
          
| 36115831 | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation | Jiang J | 2022 Sep 17 | 
                  
  | 
          
| 35971553 | Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways | Zhao F | 2022 Sep 16 | 
                  
  | 
          
| 36103542 | Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response | Dickey TH | 2022 Sep 16 | 
                  
  | 
          
| 36109732 | A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode | Zhao D | 2022 Sep 15 | 
                  
  | 
          
| 36106687 | Crystal structure and sugar-binding ability of the C-terminal domain of N-acetylglucosaminyltransferase IV establish a new carbohydrate-binding module family | Oka N | 2022 Sep 15 | 
                  
  | 
          
| 36104594 | The value of injectable viscoelastic supplements for joints | Bowden DJ | 2022 Sep 14 | 
                  
  | 
          
| 36104770 | O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy | Lu Q | 2022 Sep 14 | 
                  
  | 
          
| 35977542 | Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses | McLeod B | 2022 Sep 13 | 
                  
  | 
          
| 35952670 | Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus | Sangesland M | 2022 Sep 13 | 
                  
  | 
          
| Title | Authors | Source | Publication Date | PubMed ID | 
|---|---|---|---|---|
| Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation. | 
                  
  | 
                    J Am Chem Soc | 2003 Jun 4 | 12769553 | 
| Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line. | 
                  
  | 
                    Biochim Biophys Acta | 1999 Oct 18 | 10572927 | 
| Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. | 
                  
  | 
                    J Biol Chem | 1999 Nov 5 | 10542233 | 
| An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro. | 
                  
  | 
                    J Biol Chem | 1999 May 21 | 10329728 | 
| Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine. | 
                  
  | 
                    J Biol Chem | 1992 Jan 5 | 1730617 | 
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Partly supported by NIH Common Fund Grant #1U01GM125267-01
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