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G49108TO

Summary

GlyTouCan ID: G49108TO
IUPAC Condensed: GlcNAc(b1-

External Links

GlyConnect structure

8849

GlyGen

G49108TO

ChEBI

28009

PubChem Compound

24139

PubChem Substance

252288111

The Human Metabolome Database

HMDB0000803

3D Structures

GLYCAM: DGlcpNAcb1-OH

GlycoShape

G49108TO

Displaying 1 entry
Archetype	α	β
G14843DJ	G68544GH	G49108TO

Organisms

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Organisms	Evidence
Mus musculus (house mouse)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Rattus norvegicus (Norway rat)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Homo sapiens (human)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlyTouCan(glycome-db) GlycoEpitope
Drosophila melanogaster (fruit fly)	GlyGen(OGlcNAcDB)
Streptococcus pneumoniae	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Negarnaviricota [inference]

Polyploviricotina [inference]

Insthoviricetes [inference]

Articulavirales [inference]

Orthomyxoviridae [inference]

unclassified Orthomyxoviridae [inference]

unidentified influenza virus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT2	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT1	UDP-Gal	G49108TO	R	G00055MO	R	3014508
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B4GALT3	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT4	UDP-Gal	G49108TO	[beta]-1-Benzl	G00055MO	[beta]-1-Benzl	9792633
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT4	UDP-Gal	G49108TO	[beta]-1-4-methyl-umbelliferyl	G00055MO	[beta]-1-4-methyl-umbelliferyl	9792633

Displaying entries **1 - 5** of 24 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL2	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G49108TO	benzyl	11062056
ST6GAL1	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
CHST7	PAPS	G49108TO	-O-CH3	10781596
CHST3	PAPS	G49108TO	-O-CH3	10781596

KEGG BRITE Database

KEGG ID

Enzyme

2.4.1.255

Core Protein

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UniProt ID	Protein Name	Reference	Source
E9PVW1	Zinc finger with KRAB and SCAN domains 7	30059200	GlyGen The O-GlcNAc Database
E9PVX6	Proliferation marker protein Ki-67	22645316 34887587 36852467 39627609	The O-GlcNAc Database
E9PWM3	Armadillo repeat containing, X-linked 4		GlyGen
E9PX68	Solute carrier family 4 (anion exchanger), member 1, adaptor protein	30059200	GlyGen
E9PYK3	Protein mono-ADP-ribosyltransferase PARP4	30059200	GlyGen The O-GlcNAc Database
E9PYL2	Proline-rich protein 12	30059200	GlyGen
E9PZ19	Protein turtle homolog B		GlyGen
E9PZP8	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1		GlyGen
E9PZQ0	Ryanodine receptor 1	35469018	The O-GlcNAc Database
E9Q016	Rab40C, member RAS oncogene family	30016717	The O-GlcNAc Database

GlycoEpitope

Epitope ID: EP0004

Pathway

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Pathway Name	Organism
E.coli O58	Escherichia coli
E.coli O64	Escherichia coli
E.coli O74	Escherichia coli
E.coli O75	Escherichia coli
E.coli O78	Escherichia coli
E.coli O82	Escherichia coli
E.coli O83	Escherichia coli
E.coli O85	Escherichia coli
E.coli O88	Escherichia coli
E.coli O91	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/

Literature

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PubMed ID	Title	First Author	Publication Date	Source
35288161	OGT as potential novel target: Structure, function and inhibitors	Zhang N	2022 Apr 25	PubChem
35547740	Nanobodies Protecting From Lethal SARS-CoV-2 Infection Target Receptor Binding Epitopes Preserved in Virus Variants Other Than Omicron	Casasnovas JM	2022 Apr 25	PubChem
35324257	Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529	Zhou T	2022 Apr 22	PubChem
35443747	Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses	Wang Y	2022 Apr 21	PubChem
35357812	O-GlcNAcase Inhibitor ASN90 is a Multimodal Drug Candidate for Tau and alpha-Synuclein Proteinopathies	Permanne B	2022 Apr 20	GlyGen PubChem
35139364	Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor	Zarkadas E	2022 Apr 20	PubChem
35440630	Structure, gating, and pharmacology of human CaV3.3 channel	He L	2022 Apr 19	PubChem
35427157	Cln5 represents a new type of cysteine-based S -depalmitoylase linked to neurodegeneration	Luebben AV	2022 Apr 15	PubChem
35299116	From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series	Meden A	2022 Apr 15	PubChem
35291264	RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants	Liang Q	2022 Apr 15	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation.	Lamarre-Vincent N Hsieh-Wilson LC	J Am Chem Soc	2003 Jun 4	12769553
Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line.	Lefebvre T Alonso C Mahboub S Dupire MJ Zanetta JP Caillet-Boudin ML Michalski JC	Biochim Biophys Acta	1999 Oct 18	10572927
Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats.	Kreppel LK Hart GW	J Biol Chem	1999 Nov 5	10542233
An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro.	Su K Roos MD Yang X Han I Paterson AJ Kudlow JE	J Biol Chem	1999 May 21	10329728
Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine.	Roquemore EP Dell A Morris HR Panico M Reason AJ Savoy LA Wistow GJ Zigler JS Jr Earles BJ Hart GW	J Biol Chem	1992 Jan 5	1730617

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements