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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| Q9ERQ3 | Zinc finger protein 704 | ||
| Q9ERU9 | E3 SUMO-protein ligase RanBP2 | ||
| Q9ES00 | Ubiquitin conjugation factor E4 B | ||
| Q9ES03 | T-box transcription factor TBX20 | ||
| Q9ES28 | Rho guanine nucleotide exchange factor 7 | ||
| Q9ES97 | Reticulon-3 | ||
| Q9ESC8 | AF4/FMR2 family member 4 | ||
| Q9ESJ0 | Exportin-4 | ||
| Q9ESJ4 | NCK-interacting protein with SH3 domain | ||
| Q9ESK9 | RB1-inducible coiled-coil protein 1 |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Rattus norvegicus |
| Initial triggering of complement | Sus scrofa |
| Initial triggering of complement | Xenopus tropicalis |
| Initial triggering of complement | Gallus gallus |
| Initial triggering of complement | Homo sapiens |
| Initial triggering of complement | Bos taurus |
| Initial triggering of complement | Mus musculus |
| Initial triggering of complement | Rattus norvegicus |
| Initial triggering of complement | Canis familiaris |
| Lectin pathway of complement activation | Sus scrofa |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 37087894 | Optimization of an α-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches | Feder D | 2023 Jun 05 |
|
| 37270609 | Structural mapping of Nav1.7 antagonists | Wu Q | 2023 Jun 03 |
|
| 37334838 | An O-GlcNAc transferase pathogenic variant linked to intellectual disability affects pluripotent stem cell self-renewal | Omelková M | 2023 Jun 01 |
|
| 37260384 | Exploring the Catalytic Flexibility and Reversibility of Plant Glycosyltransferase HtUGT72AS1 for Glycodiversification of Phenolic Compounds | Wen C | 2023 Jun 01 |
|
| 37264005 | Structural interplay of anesthetics and paralytics on muscle nicotinic receptors | Goswami U | 2023 Jun 01 |
|
| 37328286 | A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer | Liu J | 2023 Jun |
|
| 37088134 | Nanobody inhibitors of Plexin-B1 identify allostery in plexin–semaphorin interactions and signaling | Cowan R | 2023 Jun |
|
| 36796536 | O-GlcNAcylation regulates phagocytosis by promoting Ezrin localization at the cell cortex | Yang S | 2023 Jul |
|
| 37494438 | Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor | Chia WN | 2023 Jul 28 |
|
| 37507370 | Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine | Guo S | 2023 Jul 28 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation. |
|
J Am Chem Soc | 2003 Jun 4 | 12769553 |
| Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line. |
|
Biochim Biophys Acta | 1999 Oct 18 | 10572927 |
| Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. |
|
J Biol Chem | 1999 Nov 5 | 10542233 |
| An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro. |
|
J Biol Chem | 1999 May 21 | 10329728 |
| Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine. |
|
J Biol Chem | 1992 Jan 5 | 1730617 |
