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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Rattus norvegicus |
| Initial triggering of complement | Sus scrofa |
| Initial triggering of complement | Xenopus tropicalis |
| Initial triggering of complement | Gallus gallus |
| Initial triggering of complement | Homo sapiens |
| Initial triggering of complement | Bos taurus |
| Initial triggering of complement | Mus musculus |
| Initial triggering of complement | Rattus norvegicus |
| Initial triggering of complement | Canis familiaris |
| Lectin pathway of complement activation | Sus scrofa |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 39531497 | Ultradeep O-GlcNAc proteomics reveals widespread O-GlcNAcylation on tyrosine residues of proteins | Hou C | 2024 Nov 12 |
|
| 39532904 | Structures of complete extracellular assemblies of type I and type II Oncostatin M receptor complexes | Zhou Y | 2024 Nov 12 |
|
| 39509538 | Opportunities for Therapeutic Modulation of O-GlcNAc | Cheng SS | 2024 Nov 07 |
|
| 39511418 | Mechanistic study of SCOOPs recognition by MIK2–BAK1 complex reveals the role of N-glycans in plant ligand–receptor–coreceptor complex formation | Wu H | 2024 Nov 07 |
|
| 39503754 | TMEM106B amyloid filaments in the Biondi bodies of ependymal cells | Ghetti B | 2024 Nov 06 |
|
| 39594580 | Modifying the Glycocalyx of Melanoma Cells via Metabolic Glycoengineering Using N-Acetyl-d-glucosamine Analogues | Harris D | 2024 Nov 06 |
|
| 38631666 | Crystal Structure of Bimekizumab Fab Fragment in Complex with IL-17F Provides Molecular Basis for Dual IL-17A and IL-17F Inhibition | Adams R | 2024 Nov |
|
| 39414231 | From Fringe to the Mainstream: How ETD MS Brought O-GlcNAc to the Masses | Udeshi ND | 2024 Nov |
|
| 39304040 | Structural and biochemical insights into the molecular mechanism of N-acetylglucosamine/N-Acetylmuramic acid kinase MurK from Clostridium acetobutylicum | He X | 2024 Nov |
|
| 39395807 | O-GlcNAcylation of ribosome-associated proteins is concomitant with translational reprogramming during proteotoxic stress | Zeidan Q | 2024 Nov |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation. |
|
J Am Chem Soc | 2003 Jun 4 | 12769553 |
| Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line. |
|
Biochim Biophys Acta | 1999 Oct 18 | 10572927 |
| Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. |
|
J Biol Chem | 1999 Nov 5 | 10542233 |
| An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro. |
|
J Biol Chem | 1999 May 21 | 10329728 |
| Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine. |
|
J Biol Chem | 1992 Jan 5 | 1730617 |
