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Glycan Structure Repository
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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| Q9Y3I0 | RNA-splicing ligase RtcB homolog | ||
| Q9Y3I1 | F-box only protein 7 | ||
| Q9Y3L3 | SH3 domain-binding protein 1 | ||
| Q9Y3M8 | StAR-related lipid transfer protein 13 | ||
| Q9Y3N9 | Olfactory receptor 2W1 | ||
| Q9Y3P8 | Signaling threshold-regulating transmembrane adapter 1 | ||
| Q9Y3R0 | Glutamate receptor-interacting protein 1 | ||
| Q9Y3S1 | Serine/threonine-protein kinase WNK2 | ||
| Q9Y3T9 | Nucleolar complex protein 2 homolog | ||
| Q9Y3Y2 | Chromatin target of PRMT1 protein |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Rattus norvegicus |
| Initial triggering of complement | Sus scrofa |
| Initial triggering of complement | Xenopus tropicalis |
| Initial triggering of complement | Gallus gallus |
| Initial triggering of complement | Homo sapiens |
| Initial triggering of complement | Bos taurus |
| Initial triggering of complement | Mus musculus |
| Initial triggering of complement | Rattus norvegicus |
| Initial triggering of complement | Canis familiaris |
| Lectin pathway of complement activation | Sus scrofa |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 35227760 | O-GlcNAc transferase promotes the nuclear localization of the focal adhesion-associated protein Zyxin to regulate UV-induced cell death | Zhao Y | 2022 Apr |
|
| 35874946 | Structural basis of SARS-CoV-2 and its variants binding to intermediate horseshoe bat ACE2 | Tang L | 2022 |
|
| 36151491 | Membrane Fractionation by Isopycnic Sucrose Density Gradient Centrifugation for Qualitative Analysis of LPS in Escherichia coli | Cardoso Mendes Moura EC | 2022 |
|
| 35379435 | Applications of an inactive Dispersin B probe to monitor biofilm polysaccharide production | Eddenden A | 2022 |
|
| 35468615 | Nanomolar Responsiveness of Marine Phaeobacter inhibens DSM 17395 toward Carbohydrates and Amino Acids | Weiten A | 2022 |
|
| 34987630 | Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2 | Huang KA | 2022 |
|
| 35844792 | O-GlcNAcylation of ZEB1 facilitated mesenchymal pancreatic cancer cell ferroptosis | Wang X | 2022 |
|
| 34986481 | miR-27b-3p Improved High Glucose-Induced Spermatogenic Cell Damage via Regulating Gfpt1/HBP Signaling | Zheng H | 2022 |
|
| 35822049 | Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases | Huynh VN | 2021 |
|
| 32798372 | Phosphorylated and O-GlcNAc Modified IRS-1 (Ser1101) and -2 (Ser1149) Contribute to Human Diabetes Type II | Kaleem A | 2021 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation. |
|
J Am Chem Soc | 2003 Jun 4 | 12769553 |
| Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line. |
|
Biochim Biophys Acta | 1999 Oct 18 | 10572927 |
| Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. |
|
J Biol Chem | 1999 Nov 5 | 10542233 |
| An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro. |
|
J Biol Chem | 1999 May 21 | 10329728 |
| Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine. |
|
J Biol Chem | 1992 Jan 5 | 1730617 |
