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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| Q9Z0R4 | Intersectin-1 | ||
| Q9Z0R6 | Intersectin-2 | ||
| Q9Z0U1 | Tight junction protein 2 | ||
| Q9Z0V6 | Thioredoxin-dependent peroxide reductase, mitochondrial | ||
| Q9Z0Z7 | Krueppel-like factor 5 | ||
| Q9Z103 | Activity-dependent neuroprotector homeobox protein | ||
| Q9Z176 | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit delta | ||
| Q9Z180 | SET-binding protein | ||
| Q9Z188 | Dual specificity tyrosine-phosphorylation-regulated kinase 1B | ||
| Q9Z1A1 | TFG protein |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Lectin pathway of complement activation | Mus musculus |
| Lectin pathway of complement activation | Bos taurus |
| Lectin pathway of complement activation | Rattus norvegicus |
| Lectin pathway of complement activation | Xenopus tropicalis |
| Lectin pathway of complement activation | Gallus gallus |
| Lectin pathway of complement activation | Homo sapiens |
| Lectin pathway of complement activation | Canis familiaris |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 38232633 | Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted | Acar DD | 2024 Feb |
|
| 37972902 | Development of a two-enzyme system in Aspergillus niger for efficient production of N-acetyl-β-D-glucosamine from powdery chitin | Han S | 2024 Feb |
|
| 38159850 | Tools for investigating O-GlcNAc in signaling and other fundamental biological pathways | Nelson ZM | 2024 Feb |
|
| 38277719 | Microbial production of N-acetyl-D-glucosamine (GlcNAc) for versatile applications: Biotechnological strategies for green process development | Das S | 2024 Feb |
|
| 38182007 | A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression | Chrudinová M | 2024 Feb |
|
| 39053763 | Dihydroartemisinin promotes tau O-GlcNAcylation and improves cognitive function in hTau transgenic mice | Xia L | 2024 Dec 20 |
|
| 39383863 | A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification | Rosen LE | 2024 Dec 12 |
|
| 39488210 | Isolation and escape mapping of broadly neutralizing antibodies against emerging delta-coronaviruses | Rexhepaj M | 2024 Dec 10 |
|
| 39516052 | Increased O-GlcNAcylation connects metabolic to transcriptional reprogramming during pathophysiological cell activation | Very N | 2024 Dec |
|
| 39481848 | Multi-omics after O-GlcNAc alteration identified cellular processes promoting aneuploidy after loss of O-GlcNAc transferase | Boyd SS | 2024 Dec |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Phosphorylation activates master growth regulator DELLA by promoting histone H2A binding at chromatin in Arabidopsis. |
|
Nat Commun | 2024 Sep 3 | 39227587 |
| A protein O-GlcNAc glycosyltransferase regulates the antioxidative response in Yersinia pestis. |
|
Nat Commun | 2024 Aug 16 | 39152136 |
| Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis. |
|
Nat Commun | 2017 Dec 5 | 29208956 |
| Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation. |
|
J Biol Chem | 2016 Jun 17 | 27129262 |
| The making of a sweet modification: structure and function of O-GlcNAc transferase. |
|
J Biol Chem | 2014 Dec 12 | 25336649 |
