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Glycan Structure Repository
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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Lectin pathway of complement activation | Mus musculus |
| Lectin pathway of complement activation | Bos taurus |
| Lectin pathway of complement activation | Rattus norvegicus |
| Lectin pathway of complement activation | Xenopus tropicalis |
| Lectin pathway of complement activation | Gallus gallus |
| Lectin pathway of complement activation | Homo sapiens |
| Lectin pathway of complement activation | Canis familiaris |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 35714668 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection | Cao Y | 2022 Jun 17 |
|
| 35607524 | Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants | Li Y | 2022 Jun 17 |
|
| 35714192 | Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody | Callaway HM | 2022 Jun 17 |
|
| 35710838 | Structural insights into the lysophospholipid brain uptake mechanism and its inhibition by syncytin-2 | Martinez-Molledo M | 2022 Jun 16 |
|
| 35653492 | Author response for 'Structural basis for the inhibition of human angiotensin‐1 converting enzyme by fosinoprilat' | Gyles E | 2022 Jun 16 |
|
| 35705054 | Spatial and temporal proteomics reveals the distinct distributions and dynamics of O-GlcNAcylated proteins | Xu S | 2022 Jun 14 |
|
| 35447092 | Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins | Wang Z | 2022 Jun 14 |
|
| 35701470 | Global O-GlcNAcylation changes impact desmin phosphorylation and its partition toward cytoskeleton in C2C12 skeletal muscle cells differentiated into myotubes | Claeyssen C | 2022 Jun 14 |
|
| 35290457 | Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH1 | Tsukamoto Y | 2022 Jun 13 |
|
| 35696580 | Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus | Banerjee A | 2022 Jun 13 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Blocking O-linked GlcNAc cycling in Drosophila insulin-producing cells perturbs glucose-insulin homeostasis. |
|
J Biol Chem | 2010 Dec 3 | 20926386 |
| Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase. |
|
J Biol Chem | 2002 Jan 18 | 11788610 |
| Increased N-acetyl-beta-glucosaminidase activity in primary breast carcinomas corresponds to a decrease in N-acetylglucosamine containing proteins. |
|
Biochim Biophys Acta | 2001 Sep 28 | 11566258 |
| Clathrin assembly protein AP-3 is phosphorylated and glycosylated on the 50-kDa structural domain. |
|
J Biol Chem | 1994 Aug 19 | 8063760 |
