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G49108TO

Summary

GlyTouCan ID: G49108TO
IUPAC Condensed: GlcNAc(b1-

3D Structures

GlycoNAVI: G49108TO
GLYCAM: DGlcpNAcb1-OH

GlycoShape

G49108TO

Displaying 1 entry
Archetype	α	β
G14843DJ	G68544GH	G49108TO

Organisms

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Organisms	Evidence
Mus musculus (house mouse)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Rattus norvegicus (Norway rat)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Homo sapiens (human)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlyTouCan(glycome-db) GlycoEpitope
Drosophila melanogaster (fruit fly)	GlyGen(OGlcNAcDB)
Streptococcus pneumoniae	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Negarnaviricota [inference]

Polyploviricotina [inference]

Insthoviricetes [inference]

Articulavirales [inference]

Orthomyxoviridae [inference]

unclassified Orthomyxoviridae [inference]

unidentified influenza virus

GlycoGene Database (GGDB)

Displaying entries **1 - 5** of 10 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT2	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT1	UDP-Gal	G49108TO	R	G00055MO	R	3014508
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B4GALT3	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT4	UDP-Gal	G49108TO	[beta]-1-Benzl	G00055MO	[beta]-1-Benzl	9792633
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT4	UDP-Gal	G49108TO	[beta]-1-4-methyl-umbelliferyl	G00055MO	[beta]-1-4-methyl-umbelliferyl	9792633

Displaying entries **1 - 5** of 24 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL2	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G49108TO	benzyl	11062056
ST6GAL1	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
CHST7	PAPS	G49108TO	-O-CH3	10781596
CHST3	PAPS	G49108TO	-O-CH3	10781596

KEGG BRITE Database

KEGG ID

Enzyme

2.4.1.255

Core Protein

Displaying entries **111 - 120** of **7284** in total

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UniProt ID	Protein Name	Reference	Source
A6NC97	Putative protein ARB2BP	38253038	The O-GlcNAc Database
A6NCM1	IQ and AAA domain-containing protein 1-like	31492838	The O-GlcNAc Database
A6NCW0	Ubiquitin carboxyl-terminal hydrolase 17-like protein 3	38253038	The O-GlcNAc Database
A6NDG6	Glycerol-3-phosphate phosphatase	23301498 28510447 30379171 34019948 34229054	GlyGen The O-GlcNAc Database
A6NDL7	Putative methyltransferase-like protein 21E pseudogene	29351928	The O-GlcNAc Database
A6NE01	Protein FAM186A	30379171	GlyGen The O-GlcNAc Database
A6NED2	RCC1 domain-containing protein 1	37340703	The O-GlcNAc Database
A6NEL2	Ankyrin repeat domain-containing protein SOWAHB	29351928 32574038 37217939	GlyGen The O-GlcNAc Database
A6NF01	Putative nuclear envelope pore membrane protein POM 121B	29351928 30620550 35254053 35289036 39531497	GlyGen The O-GlcNAc Database
A6NFQ2	TRPM8 channel-associated factor 2	29351928	The O-GlcNAc Database

GlycoEpitope

Epitope ID: EP0004

Pathway

Displaying entries **11 - 20** of **127** in total

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Pathway Name	Organism
Antimicrobial peptides	Rattus norvegicus
E.coli O10	Escherichia coli
E.coli O103	Escherichia coli
E.coli O105	Escherichia coli
E.coli O109	Escherichia coli
E.coli O110	Escherichia coli
E.coli O111	Escherichia coli
E.coli O112ab	Escherichia coli
E.coli O113	Escherichia coli
E.coli O115	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/

Literature

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PubMed ID	Title	First Author	Publication Date	Source
36708708	Structure of the Inmazeb cocktail and resistance to escape against Ebola virus	Rayaprolu V	2023 Jan 25	PubChem
36714014	Design of hACE2-based small peptide inhibitors against spike protein of SARS-CoV-2: a computational approach	Dhingra N	2023 Jan 25	PubChem
37247228	Author response for 'Identification of a diketopiperazine‐based <scp>O‐GlcNAc</scp> transferase inhibitor sensitizing hepatocellular carcinoma to <scp>CDK9</scp> inhibition'	Shan Xiaoqun	2023 Jan 24	GlyGen PubChem
36533564	4‐O‐Substituted Glucuronic Cyclophellitols are Selective Mechanism‐Based Heparanase Inhibitors	Borlandelli V	2023 Jan 24	PubChem
36583658	Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids	Gomez de Santos P	2023 Jan 24	PubChem
36689079	Aberrant N-glycosylation in cancer: MGAT5 and β1,6-GlcNAc branched N-glycans as critical regulators of tumor development and progression	de-Souza-Ferreira M	2023 Jan 23	PubChem
36768465	Emerging Role of Protein O-GlcNAcylation in Liver Metabolism: Implications for Diabetes and NAFLD	Xie Z	2023 Jan 21	PubChem
36514310	Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD	Chen Y	2023 Jan 20	PubChem
36626902	Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin	Zhu Y	2023 Jan 19	PubChem
36640760	Autotaxin facilitates selective LPA receptor signaling	Salgado-Polo F	2023 Jan 19	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Phosphorylation activates master growth regulator DELLA by promoting histone H2A binding at chromatin in Arabidopsis.	Huang X Zentella R Park J Reser L Bai DL Ross MM Shabanowitz J Hunt DF Sun TP	Nat Commun	2024 Sep 3	39227587
A protein O-GlcNAc glycosyltransferase regulates the antioxidative response in Yersinia pestis.	Cao S Wang T Ren Y Wu G Zhang Y Tan Y Zhou Y Chen H Zhang Y Song Y Yang R Du Z	Nat Commun	2024 Aug 16	39152136
Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis.	Ma X Liu H Li J Wang Y Ding YH Shen H Yang Y Sun C Huang M Tu Y Liu Y Zhao Y Dong MQ Xu P Tang TS Guo C	Nat Commun	2017 Dec 5	29208956
Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation.	Lucena MC Carvalho-Cruz P Donadio JL Oliveira IA de Queiroz RM Marinho-Carvalho MM Sola-Penna M de Paula IF Gondim KC McComb ME Costello CE Whelan SA Todeschini AR Dias WB	J Biol Chem	2016 Jun 17	27129262
The making of a sweet modification: structure and function of O-GlcNAc transferase.	Janetzko J Walker S	J Biol Chem	2014 Dec 12	25336649

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements