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G49108TO

Summary

GlyTouCan ID: G49108TO
IUPAC Condensed: GlcNAc(b1-

External Links

GlyConnect structure

8849

GlyGen

G49108TO

ChEBI

28009

PubChem Compound

24139

PubChem Substance

252288111

The Human Metabolome Database

HMDB0000803

3D Structures

GlycoNAVI: G49108TO
GLYCAM: DGlcpNAcb1-OH

GlycoShape

G49108TO

Displaying 1 entry
Archetype	α	β
G14843DJ	G68544GH	G49108TO

Organisms

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Organisms	Evidence
Mus musculus (house mouse)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Rattus norvegicus (Norway rat)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Homo sapiens (human)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlyTouCan(glycome-db) GlycoEpitope
Drosophila melanogaster (fruit fly)	GlyGen(OGlcNAcDB)
Streptococcus pneumoniae	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Negarnaviricota [inference]

Polyploviricotina [inference]

Insthoviricetes [inference]

Articulavirales [inference]

Orthomyxoviridae [inference]

unclassified Orthomyxoviridae [inference]

unidentified influenza virus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT2	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT1	UDP-Gal	G49108TO	R	G00055MO	R	3014508
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B4GALT3	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT4	UDP-Gal	G49108TO	[beta]-1-Benzl	G00055MO	[beta]-1-Benzl	9792633
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT4	UDP-Gal	G49108TO	[beta]-1-4-methyl-umbelliferyl	G00055MO	[beta]-1-4-methyl-umbelliferyl	9792633

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL2	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G49108TO	benzyl	11062056
ST6GAL1	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
CHST7	PAPS	G49108TO	-O-CH3	10781596
CHST3	PAPS	G49108TO	-O-CH3	10781596

KEGG BRITE Database

KEGG ID

Enzyme

2.4.1.255

Core Protein

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UniProt ID	Protein Name	Reference	Source
Q9Y4G2	Pleckstrin homology domain-containing family M member 1	29351928	The O-GlcNAc Database
Q9Y4G6	Talin-2	30379171 31637018	GlyGen The O-GlcNAc Database
Q9Y4G8	Rap guanine nucleotide exchange factor 2	28657654 29237092 29351928 30059200 30620550 31492838 35254053 39302247 39531497	GlyGen The O-GlcNAc Database
Q9Y4H2	Insulin receptor substrate 2	23301498 30059200 31373491 32798372 35254053 35289036 36240223 37217939	GlyGen The O-GlcNAc Database
Q9Y4K1	Beta/gamma crystallin domain-containing protein 1	29351928 30379171 31492838 34019948 35132862 35254053 38253038 38665916 39302247 39531497 39534244	GlyGen The O-GlcNAc Database
Q9Y4L1	Hypoxia up-regulated protein 1	21526146 22661428 29249144 30059200 30397120 30444036 30620550 32119511 33214551 33465208 34019948 34229054 34725712 35008409 35132862 35138101 35254053 37217939 38665916 39531497 39534244	GlyGen The O-GlcNAc Database
Q9Y4R7	Tubulin monoglycylase TTLL3	30620550	GlyGen The O-GlcNAc Database
Q9Y4W2	Ribosomal biogenesis protein LAS1L	23301498 28510447 30379171 32522876 35083852	GlyGen The O-GlcNAc Database
Q9Y512	Sorting and assembly machinery component 50 homolog	28411811 28510447 33465208 35254053	GlyGen The O-GlcNAc Database
Q9Y520	Protein PRRC2C	20068230 20305658 21740066 22661428 23301498 27114449 27655845 28314751 28510447 28657654 29237092 29351928 30059200 30379171 30620550 31373491 31492838 32119511 32574038 32870666 33214551 34019948 34229054 34725712 34931806 35132862 35138101 35254053 35289036 37340703 38253038 38665916 39302247 39531497 39534244	GlyGen The O-GlcNAc Database GlyConnect

GlycoEpitope

Epitope ID: EP0004

Pathway

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Pathway Name	Organism
E.coli O116	Escherichia coli
E.coli O118	Escherichia coli
E.coli O12	Escherichia coli
E.coli O126	Escherichia coli
E.coli O126H27	Escherichia coli
E.coli O129	Escherichia coli
E.coli O13	Escherichia coli
E.coli O132	Escherichia coli
E.coli O135	Escherichia coli
E.coli O136	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/

Literature

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PubMed ID	Title	First Author	Publication Date	Source
6894523	Nuclear magnetic resonance studies on wheat germ agglutinin-monomeric amino sugar interactions	Jordan F	1981 Mar	PubChem
7240189	Glycoprotein biosynthesis in calf pituitary. Chemical characterization of mannose- and glucose-radiolabeled oligosaccharides.	Henner JA	1981 Jun 25	PubChem
6820440	Aspartylglycosaminuria: An inborn error of glycoprotein catabolism	Maury CP	1981 Jun 08	PubChem
6461214	[Effect of colchicine and cytochalasin B on cell agglutination of experimental hepatoma (author's transl)]	Wang ZW	1981 Jun	PubChem
6895524	A light and electron microscopic study of the intraneuronal transport of horseradish peroxidase and wheat germ agglutinin-peroxidase conjugates in the rat visual system	Trojanowski JQ	1981 Jun	PubChem
7240086	Effect of Long Generation Times on Growth ofBacteroides thetaiotaomicronin Carbohydrate-Limited Continuous Culture	Kotarski SF	1981 Jun	PubChem
7248176	Synthesis and turnover of membrane glycoconjugates in monolayer culture of pig and human epidermal cells	Davies HW	1981 Jun	PubChem
7295318	Human salivary fucosyltransferases : evidence for two distinct alpha-3-L-fucosyltransferase activities one or which is associated with the Lewis blood group Le gene	Johnson PH	1981 Jun	PubChem
6268947	Glycoprotein of Hepatitis B Surface Antigen (HBsAg) Produced by PLC/PRF/5 Hepatoma Cells	Nakagomi O	1981 Jun	PubChem
6943974	STRUCTURAL STUDIES ON A BIOLOGICALLY ACTIVE HEXASACCHARIDE OBTAINED FROM HEPARIN	Choay J	1981 Jun	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Phosphorylation activates master growth regulator DELLA by promoting histone H2A binding at chromatin in Arabidopsis.	Huang X Zentella R Park J Reser L Bai DL Ross MM Shabanowitz J Hunt DF Sun TP	Nat Commun	2024 Sep 3	39227587
A protein O-GlcNAc glycosyltransferase regulates the antioxidative response in Yersinia pestis.	Cao S Wang T Ren Y Wu G Zhang Y Tan Y Zhou Y Chen H Zhang Y Song Y Yang R Du Z	Nat Commun	2024 Aug 16	39152136
Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis.	Ma X Liu H Li J Wang Y Ding YH Shen H Yang Y Sun C Huang M Tu Y Liu Y Zhao Y Dong MQ Xu P Tang TS Guo C	Nat Commun	2017 Dec 5	29208956
Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation.	Lucena MC Carvalho-Cruz P Donadio JL Oliveira IA de Queiroz RM Marinho-Carvalho MM Sola-Penna M de Paula IF Gondim KC McComb ME Costello CE Whelan SA Todeschini AR Dias WB	J Biol Chem	2016 Jun 17	27129262
The making of a sweet modification: structure and function of O-GlcNAc transferase.	Janetzko J Walker S	J Biol Chem	2014 Dec 12	25336649

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements