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Glycan Structure Repository
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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| U3KPZ7 | RNA-binding protein 27 | ||
| V6CIU7 | choline-phosphate cytidylyltransferase | ||
| V6CKC3 | C2H2-type domain-containing protein | ||
| V9GYH0 | Homeobox domain-containing protein (Fragment) |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| E.coli O137 | Escherichia coli |
| E.coli O138 | Escherichia coli |
| E.coli O141 | Escherichia coli |
| E.coli O142 | Escherichia coli |
| E.coli O143 | Escherichia coli |
| E.coli O145 | Escherichia coli |
| E.coli O149 | Escherichia coli |
| E.coli O15 | Escherichia coli |
| E.coli O150 | Escherichia coli |
| E.coli O151 | Escherichia coli |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 36266488 | Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth | Wang Z | 2022 Oct 20 |
|
| 36080360 | Crystal structure of human CD47 in complex with engineered SIRPa.D1(N80A) | Yu J | 2022 Oct 19 |
|
| 36261433 | Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor | Bayly-Jones C | 2022 Oct 19 |
|
| 36257932 | Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism | Kobberø SD | 2022 Oct 18 |
|
| 36254612 | The Inflammation Biomarker GlycA Reflects Plasma N-Glycan Branching | Noel M | 2022 Oct 18 |
|
| 36261006 | Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27 | Składanowska K | 2022 Oct 18 |
|
| 36260993 | IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling | Goepfert A | 2022 Oct 18 |
|
| 36293310 | Mutation Hotspot for Changing the Substrate Specificity of β-N-Acetylhexosaminidase: A Library of GlcNAcases | Nekvasilová P | 2022 Oct 18 |
|
| 36251573 | Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema | Davie RL | 2022 Oct 17 |
|
| 36253376 | HIV-1 CD4-binding site germline antibody–Env structures inform vaccine design | Dam KA | 2022 Oct 17 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Phosphorylation activates master growth regulator DELLA by promoting histone H2A binding at chromatin in Arabidopsis. |
|
Nat Commun | 2024 Sep 3 | 39227587 |
| A protein O-GlcNAc glycosyltransferase regulates the antioxidative response in Yersinia pestis. |
|
Nat Commun | 2024 Aug 16 | 39152136 |
| Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis. |
|
Nat Commun | 2017 Dec 5 | 29208956 |
| Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation. |
|
J Biol Chem | 2016 Jun 17 | 27129262 |
| The making of a sweet modification: structure and function of O-GlcNAc transferase. |
|
J Biol Chem | 2014 Dec 12 | 25336649 |
