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G49108TO

Summary

GlyTouCan ID: G49108TO
IUPAC Condensed: GlcNAc(b1-

External Links

GlyConnect structure

8849

GlyGen

G49108TO

ChEBI

28009

PubChem Compound

24139

PubChem Substance

252288111

The Human Metabolome Database

HMDB0000803

3D Structures

GLYCAM: DGlcpNAcb1-OH

GlycoShape

G49108TO

Displaying 1 entry
Archetype	α	β
G14843DJ	G68544GH	G49108TO

Organisms

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Organisms	Evidence
Mus musculus (house mouse)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Rattus norvegicus (Norway rat)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Homo sapiens (human)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlyTouCan(glycome-db) GlycoEpitope
Drosophila melanogaster (fruit fly)	GlyGen(OGlcNAcDB)
Streptococcus pneumoniae	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Negarnaviricota [inference]

Polyploviricotina [inference]

Insthoviricetes [inference]

Articulavirales [inference]

Orthomyxoviridae [inference]

unclassified Orthomyxoviridae [inference]

unidentified influenza virus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT2	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT1	UDP-Gal	G49108TO	R	G00055MO	R	3014508
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B4GALT3	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT4	UDP-Gal	G49108TO	[beta]-1-Benzl	G00055MO	[beta]-1-Benzl	9792633
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT4	UDP-Gal	G49108TO	[beta]-1-4-methyl-umbelliferyl	G00055MO	[beta]-1-4-methyl-umbelliferyl	9792633

Displaying entries **1 - 5** of 24 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL2	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G49108TO	benzyl	11062056
ST6GAL1	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
CHST7	PAPS	G49108TO	-O-CH3	10781596
CHST3	PAPS	G49108TO	-O-CH3	10781596

KEGG BRITE Database

KEGG ID

Enzyme

2.4.1.255

Core Protein

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UniProt ID	Protein Name	Reference	Source
A0A061AE78	DMAP1-binding domain-containing protein	31682414	The O-GlcNAc Database
A0A087WXM9	Meiosis-specific kinetochore protein	30379171	GlyGen The O-GlcNAc Database
A0A087X1C1	Thymosin beta 15C	31492838	The O-GlcNAc Database
A0A0A6YVU8	Adhesion regulating molecule 1B	30059200 37507081	GlyGen The O-GlcNAc Database
A0A0B4J1U4	T cell receptor gamma variable 5	38253038	The O-GlcNAc Database
A0A0B4J1W7	Nuclear pore complex-interacting protein family member A9	39531497	The O-GlcNAc Database
A0A0B4J203	receptor protein-tyrosine kinase	28510447 30620550 31492838 35254053	The O-GlcNAc Database
A0A0B4J2E0	T cell receptor beta variable 12-4	38253038	The O-GlcNAc Database
A0A0C4DFX4	Snf2 related CREBBP activator protein (Fragment)	30620550 31492838 35254053	The O-GlcNAc Database
A0A0C4DH32	Immunoglobulin heavy variable 3-20	38253038	The O-GlcNAc Database

GlycoEpitope

Epitope ID: EP0004

Pathway

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Pathway Name	Organism
E.coli O137	Escherichia coli
E.coli O138	Escherichia coli
E.coli O141	Escherichia coli
E.coli O142	Escherichia coli
E.coli O143	Escherichia coli
E.coli O145	Escherichia coli
E.coli O149	Escherichia coli
E.coli O15	Escherichia coli
E.coli O150	Escherichia coli
E.coli O151	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/

Literature

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PubMed ID	Title	First Author	Publication Date	Source
36124412	Hexosamine pathway activation improves memory but does not extend lifespan in mice	Allmeroth K	2022 Sep 19	PubChem
36115831	Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation	Jiang J	2022 Sep 17	PubChem
35971553	Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways	Zhao F	2022 Sep 16	PubChem
36103542	Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response	Dickey TH	2022 Sep 16	PubChem
36109732	A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode	Zhao D	2022 Sep 15	PubChem
36106687	Crystal structure and sugar-binding ability of the C-terminal domain of N-acetylglucosaminyltransferase IV establish a new carbohydrate-binding module family	Oka N	2022 Sep 15	PubChem
36104594	The value of injectable viscoelastic supplements for joints	Bowden DJ	2022 Sep 14	PubChem
36104770	O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy	Lu Q	2022 Sep 14	PubChem
35977542	Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses	McLeod B	2022 Sep 13	PubChem
35952670	Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus	Sangesland M	2022 Sep 13	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Localization of O-GlcNAc modification on the serum response transcription factor.	Reason AJ Morris HR Panico M Marais R Treisman RH Haltiwanger RS Hart GW Kelly WG Dell A	J Biol Chem	1992 Aug 25	1512232
High-sensitivity FAB-MS strategies for O-GlcNAc characterization.	Reason AJ Blench IP Haltiwanger RS Hart GW Morris HR Panico M Dell A	Glycobiology	1991 Dec	1822238
Enzymatic addition of O-GlcNAc to nuclear and cytoplasmic proteins. Identification of a uridine diphospho-N-acetylglucosamine:peptide beta-N-acetylglucosaminyltransferase.	Haltiwanger RS Holt GD Hart GW	J Biol Chem	1990 Feb 15	2137449
O-N-acetyl-D-glucosamine moiety on discrete peptide of multiple protein 4.1 isoforms regulated by alternative pathways.	Inaba M Maede Y	J Biol Chem	1989 Oct 25	2808371
Glycosylation of chromosomal proteins: localization of O-linked N-acetylglucosamine in Drosophila chromatin.	Kelly WG Hart GW	Cell	1989 Apr 21	2495182

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements