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G49108TO

Summary

GlyTouCan ID: G49108TO
IUPAC Condensed: GlcNAc(b1-

External Links

GlyConnect structure

8849

GlyGen

G49108TO

ChEBI

28009

PubChem Compound

24139

PubChem Substance

252288111

The Human Metabolome Database

HMDB0000803

3D Structures

GLYCAM: DGlcpNAcb1-OH

GlycoShape

G49108TO

Displaying 1 entry
Archetype	α	β
G14843DJ	G68544GH	G49108TO

Organisms

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Organisms	Evidence
Mus musculus (house mouse)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Rattus norvegicus (Norway rat)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Homo sapiens (human)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlyTouCan(glycome-db) GlycoEpitope
Drosophila melanogaster (fruit fly)	GlyGen(OGlcNAcDB)
Streptococcus pneumoniae	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Negarnaviricota [inference]

Polyploviricotina [inference]

Insthoviricetes [inference]

Articulavirales [inference]

Orthomyxoviridae [inference]

unclassified Orthomyxoviridae [inference]

unidentified influenza virus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT2	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT1	UDP-Gal	G49108TO	R	G00055MO	R	3014508
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B4GALT3	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT4	UDP-Gal	G49108TO	[beta]-1-Benzl	G00055MO	[beta]-1-Benzl	9792633
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT4	UDP-Gal	G49108TO	[beta]-1-4-methyl-umbelliferyl	G00055MO	[beta]-1-4-methyl-umbelliferyl	9792633

Displaying entries **1 - 5** of 24 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL2	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G49108TO	benzyl	11062056
ST6GAL1	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
CHST7	PAPS	G49108TO	-O-CH3	10781596
CHST3	PAPS	G49108TO	-O-CH3	10781596

KEGG BRITE Database

KEGG ID

Enzyme

2.4.1.255

Core Protein

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UniProt ID	Protein Name	Reference	Source
O43561	Linker for activation of T-cells family member 1	29351928 37217939 38253038	GlyGen The O-GlcNAc Database
O43567	E3 ubiquitin-protein ligase RNF13	28657654 29485866 35254053 38665916	GlyGen The O-GlcNAc Database
O43597	Protein sprouty homolog 2	35254053	GlyGen The O-GlcNAc Database
O43613	Orexin/Hypocretin receptor type 1	29351928	The O-GlcNAc Database
O43615	Mitochondrial import inner membrane translocase subunit TIM44	33465208 34725712	GlyGen The O-GlcNAc Database
O43660	Pleiotropic regulator 1	29351928 30379171 34019948 34725712 35008409 35254053 37217939 38665916 39531497	GlyGen The O-GlcNAc Database
O43670	BUB3-interacting and GLEBS motif-containing protein ZNF207	20305658 21740066 27655845 28510447 29237092 29351928 29485866 30059200 32119511 33214551 34019948 34725712 34931806 35008409 35132862 35138101 35254053 35289036 38665916 39302247 39531497 39534244	GlyGen The O-GlcNAc Database
O43683	Mitotic checkpoint serine/threonine-protein kinase BUB1	28510447 30379171 39302247 39531497	The O-GlcNAc Database
O43684	Mitotic checkpoint protein BUB3	23301498 32119511 33214551 34019948 34725712 35008409 35083852 35132862 35138101 37217939 38665916	GlyGen The O-GlcNAc Database
O43704	Sulfotransferase 1B1	29351928	The O-GlcNAc Database

GlycoEpitope

Epitope ID: EP0004

Pathway

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Pathway Name	Organism
E.coli O4-H5	Escherichia coli
E.coli O4-K52	Escherichia coli
E.coli O40	Escherichia coli
E.coli O41	Escherichia coli
E.coli O42	Escherichia coli
E.coli O45rel	Escherichia coli
E.coli O48	Escherichia coli
E.coli O53	Escherichia coli
E.coli O55	Escherichia coli
E.coli O56	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/

Literature

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PubMed ID	Title	First Author	Publication Date	Source
35014594	N-acetylglucosamine-phosphatidylinositol de-N-acetylase as a novel target for probing potential inhibitor against Leishmania donovani	Kumar M	2022 Jan 11	PubChem
35013249	Cryo-EM structure of native human thyroglobulin	Adaixo R	2022 Jan 10	PubChem
35001074	A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma	Kakiuchi-Kiyota S	2022 Jan 10	PubChem
35013189	A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo	Hanke L	2022 Jan 10	PubChem
34793197	Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies	Mishra AK	2022 Jan 07	PubChem
35069563	Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s	Tolbert WD	2022 Jan 06	PubChem
35008409	Comparative O-GlcNAc Proteomic Analysis Reveals a Role of O-GlcNAcylated SAM68 in Lung Cancer Aggressiveness	Lin CH	2022 Jan 04	GlyGen PubChem
34982225	Paenibacillus arenosi sp. nov., a siderophore-producing bacterium isolated from coastal sediment	Baek J	2022 Jan 04	PubChem
34978456	Total Chemical Synthesis of Correctly Folded Disulfide-Rich Proteins Using a Removable O-Linked β-N-Acetylglucosamine Strategy	Shi WW	2022 Jan 03	PubChem
34922944	Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2	Nakanishi H	2022 Jan	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation.	Lamarre-Vincent N Hsieh-Wilson LC	J Am Chem Soc	2003 Jun 4	12769553
Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line.	Lefebvre T Alonso C Mahboub S Dupire MJ Zanetta JP Caillet-Boudin ML Michalski JC	Biochim Biophys Acta	1999 Oct 18	10572927
Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats.	Kreppel LK Hart GW	J Biol Chem	1999 Nov 5	10542233
An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro.	Su K Roos MD Yang X Han I Paterson AJ Kudlow JE	J Biol Chem	1999 May 21	10329728
Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine.	Roquemore EP Dell A Morris HR Panico M Reason AJ Savoy LA Wistow GJ Zigler JS Jr Earles BJ Hart GW	J Biol Chem	1992 Jan 5	1730617

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements