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Glycan Structure Repository
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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| Q9Y678 | Coatomer subunit gamma-1 | ||
| Q9Y692 | Glucocorticoid modulatory element-binding protein 1 | ||
| Q9Y6A1 | Protein O-mannosyl-transferase 1 | ||
| Q9Y6A2 | Cholesterol 24-hydroxylase | ||
| Q9Y6A5 | Transforming acidic coiled-coil-containing protein 3 | ||
| Q9Y6C2 | EMILIN-1 | ||
| Q9Y6D5 | Brefeldin A-inhibited guanine nucleotide-exchange protein 2 | ||
| Q9Y6E0 | Serine/threonine-protein kinase 24 | ||
| Q9Y6E2 | eIF5-mimic protein 1 | ||
| Q9Y6G9 | Cytoplasmic dynein 1 light intermediate chain 1 |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| E.coli O4-H5 | Escherichia coli |
| E.coli O4-K52 | Escherichia coli |
| E.coli O40 | Escherichia coli |
| E.coli O41 | Escherichia coli |
| E.coli O42 | Escherichia coli |
| E.coli O45rel | Escherichia coli |
| E.coli O48 | Escherichia coli |
| E.coli O53 | Escherichia coli |
| E.coli O55 | Escherichia coli |
| E.coli O56 | Escherichia coli |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 37903907 | The molecular basis of drug selectivity for α5 subunit-containing GABAA receptors | Kasaragod VB | 2023 Oct 30 |
|
| 37804831 | Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8 | Zimmerman O | 2023 Oct 26 |
|
| 37901798 | A potent and broad‐spectrum neutralizing nanobody for SARS‐CoV‐2 viruses, including all major Omicron strains | Yao H | 2023 Oct 26 |
|
| 37872202 | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir | Prévost J | 2023 Oct 23 |
|
| 37867237 | Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT | Tang J | 2023 Oct 22 |
|
| 37856504 | Exploiting O-GlcNAc transferase promiscuity to dissect site-specific O-GlcNAcylation | Mitchell CW | 2023 Oct 19 |
|
| 37851455 | High-Level Production of Lacto-N-neotetraose in Escherichia coli by Stepwise Optimization of the Biosynthetic Pathway | Zhang M | 2023 Oct 18 |
|
| 37848414 | O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations | Huynh DT | 2023 Oct 17 |
|
| 37842859 | Nutritional and metabolic control of germ cell fate through O‐GlcNAc regulation | Hayashi Y | 2023 Oct 16 |
|
| 37669729 | 3D printed pH-responsive tablets containing N-acetylglucosamine-loaded methylcellulose hydrogel for colon drug delivery applications | Asadi M | 2023 Oct 15 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Phosphorylation activates master growth regulator DELLA by promoting histone H2A binding at chromatin in Arabidopsis. |
|
Nat Commun | 2024 Sep 3 | 39227587 |
| A protein O-GlcNAc glycosyltransferase regulates the antioxidative response in Yersinia pestis. |
|
Nat Commun | 2024 Aug 16 | 39152136 |
| Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis. |
|
Nat Commun | 2017 Dec 5 | 29208956 |
| Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation. |
|
J Biol Chem | 2016 Jun 17 | 27129262 |
| The making of a sweet modification: structure and function of O-GlcNAc transferase. |
|
J Biol Chem | 2014 Dec 12 | 25336649 |
