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G49108TO

Summary

GlyTouCan ID: G49108TO
IUPAC Condensed: GlcNAc(b1-

External Links

GlyConnect structure

8849

GlyGen

G49108TO

ChEBI

28009

PubChem Compound

24139

PubChem Substance

252288111

The Human Metabolome Database

HMDB0000803

3D Structures

GLYCAM: DGlcpNAcb1-OH

GlycoShape

G49108TO

Displaying 1 entry
Archetype	α	β
G14843DJ	G68544GH	G49108TO

Organisms

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Organisms	Evidence
Mus musculus (house mouse)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Rattus norvegicus (Norway rat)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlycoEpitope
Homo sapiens (human)	GlyConnectStructure GlyGen(OGlcNAcAtlas) GlyGen(OGlcNAcDB) GlyGen(UniCarbKB) GlyTouCan(glycome-db) GlycoEpitope
Drosophila melanogaster (fruit fly)	GlyGen(OGlcNAcDB)
Streptococcus pneumoniae	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Terrabacteria group [inference]

Bacillota [inference]

Bacilli [inference]

Lactobacillales [inference]

Streptococcaceae [inference]

Streptococcus [inference]

Streptococcus pneumoniae

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Negarnaviricota [inference]

Polyploviricotina [inference]

Insthoviricetes [inference]

Articulavirales [inference]

Orthomyxoviridae [inference]

unclassified Orthomyxoviridae [inference]

unidentified influenza virus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT2	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT1	UDP-Gal	G49108TO	R	G00055MO	R	3014508
B3GALT5	UDP-Gal	G49108TO	R	G00056MO	R	10212226

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALT5	(not applicable)	G49108TO	[beta]-S-pNP	G00055MO	[beta]-S-pNP	9435216
B4GALT3	UDP-Gal	G49108TO	Benzyl-[beta]	G00055MO	Benzyl-[beta]	9405390
B4GALT4	UDP-Gal	G49108TO	[beta]-1-Benzl	G00055MO	[beta]-1-Benzl	9792633
B3GALT2	UDP-Gal	G49108TO	Lemieux	G00056MO	Lemieux	9417100
B4GALT4	UDP-Gal	G49108TO	[beta]-1-4-methyl-umbelliferyl	G00055MO	[beta]-1-4-methyl-umbelliferyl	9792633

Displaying entries **1 - 5** of 24 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL2	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G49108TO	benzyl	11062056
ST6GAL1	CMP-Neu5Ac	G49108TO	para-nitrophenol	12603328
CHST7	PAPS	G49108TO	-O-CH3	10781596
CHST3	PAPS	G49108TO	-O-CH3	10781596

KEGG BRITE Database

KEGG ID

Enzyme

2.4.1.255

Core Protein

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UniProt ID	Protein Name	Reference	Source
Q9Y4G2	Pleckstrin homology domain-containing family M member 1	29351928	The O-GlcNAc Database
Q9Y4G6	Talin-2	30379171 31637018	GlyGen The O-GlcNAc Database
Q9Y4G8	Rap guanine nucleotide exchange factor 2	28657654 29237092 29351928 30059200 30620550 31492838 35254053 39302247 39531497	GlyGen The O-GlcNAc Database
Q9Y4H2	Insulin receptor substrate 2	23301498 30059200 31373491 32798372 35254053 35289036 36240223 37217939	GlyGen The O-GlcNAc Database
Q9Y4K1	Beta/gamma crystallin domain-containing protein 1	29351928 30379171 31492838 34019948 35132862 35254053 38253038 38665916 39302247 39531497 39534244	GlyGen The O-GlcNAc Database
Q9Y4L1	Hypoxia up-regulated protein 1	21526146 22661428 29249144 30059200 30397120 30444036 30620550 32119511 33214551 33465208 34019948 34229054 34725712 35008409 35132862 35138101 35254053 37217939 38665916 39531497 39534244	GlyGen The O-GlcNAc Database
Q9Y4R7	Tubulin monoglycylase TTLL3	30620550	GlyGen The O-GlcNAc Database
Q9Y4W2	Ribosomal biogenesis protein LAS1L	23301498 28510447 30379171 32522876 35083852	GlyGen The O-GlcNAc Database
Q9Y512	Sorting and assembly machinery component 50 homolog	28411811 28510447 33465208 35254053	GlyGen The O-GlcNAc Database
Q9Y520	Protein PRRC2C	20068230 20305658 21740066 22661428 23301498 27114449 27655845 28314751 28510447 28657654 29237092 29351928 30059200 30379171 30620550 31373491 31492838 32119511 32574038 32870666 33214551 34019948 34229054 34725712 34931806 35132862 35138101 35254053 35289036 37340703 38253038 38665916 39302247 39531497 39534244	GlyGen The O-GlcNAc Database GlyConnect

GlycoEpitope

Epitope ID: EP0004

Pathway

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Pathway Name	Organism
Antimicrobial peptides	Xenopus tropicalis
Antimicrobial peptides	Rattus norvegicus
Antimicrobial peptides	Danio rerio
Antimicrobial peptides	Bos taurus
Antimicrobial peptides	Canis familiaris
Antimicrobial peptides	Sus scrofa
Antimicrobial peptides	Dictyostelium discoideum
Antimicrobial peptides	Mus musculus
Antimicrobial peptides	Drosophila melanogaster
Antimicrobial peptides	Homo sapiens

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/

Literature

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PubMed ID	Title	First Author	Publication Date	Source
33427997	Potassium-induced partial inhibition of lactoperoxidase: structure of the complex of lactoperoxidase with potassium ion at 2.20 Å resolution	Singh PK	2021 Jan 11	PubChem
33431842	Stabilizing the closed SARS-CoV-2 spike trimer	Juraszek J	2021 Jan 11	PubChem
33432245	Cryo-EM structures of Toll-like receptors in complex with UNC93B1	Ishida H	2021 Jan 11	PubChem
33432247	A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent	Xiao T	2021 Jan 11	PubChem
33431856	Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry	Ge J	2021 Jan 11	PubChem
33422108	Increased O-GlcNAcylation of Drp1 by amyloid-beta promotes mitochondrial fission and dysfunction in neuronal cells	Park SJ	2021 Jan 09	GlyGen PubChem
33437137	Combination and tricombination therapy to destabilize the structural integrity of COVID-19 by some bioactive compounds with antiviral drugs: insights from molecular docking study	El-Mageed HRA	2021 Jan 08	PubChem
33420071	Structures of human dual oxidase 1 complex in low-calcium and high-calcium states	Wu J	2021 Jan 08	PubChem
33214287	Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth	Roark RS	2021 Jan 08	PubChem
33420048	Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes	Song X	2021 Jan 08	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Localization of O-GlcNAc modification on the serum response transcription factor.	Reason AJ Morris HR Panico M Marais R Treisman RH Haltiwanger RS Hart GW Kelly WG Dell A	J Biol Chem	1992 Aug 25	1512232
High-sensitivity FAB-MS strategies for O-GlcNAc characterization.	Reason AJ Blench IP Haltiwanger RS Hart GW Morris HR Panico M Dell A	Glycobiology	1991 Dec	1822238
Enzymatic addition of O-GlcNAc to nuclear and cytoplasmic proteins. Identification of a uridine diphospho-N-acetylglucosamine:peptide beta-N-acetylglucosaminyltransferase.	Haltiwanger RS Holt GD Hart GW	J Biol Chem	1990 Feb 15	2137449
O-N-acetyl-D-glucosamine moiety on discrete peptide of multiple protein 4.1 isoforms regulated by alternative pathways.	Inaba M Maede Y	J Biol Chem	1989 Oct 25	2808371
Glycosylation of chromosomal proteins: localization of O-linked N-acetylglucosamine in Drosophila chromatin.	Kelly WG Hart GW	Cell	1989 Apr 21	2495182

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements