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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| Q9Y5X3 | Sorting nexin-5 | ||
| Q9Y5X4 | Photoreceptor-specific nuclear receptor | ||
| Q9Y5Y2 | Cytosolic Fe-S cluster assembly factor NUBP2 | ||
| Q9Y5Z4 | Heme-binding protein 2 | ||
| Q9Y5Z7 | Host cell factor 2 | ||
| Q9Y608 | Leucine-rich repeat flightless-interacting protein 2 | ||
| Q9Y613 | FH1/FH2 domain-containing protein 1 | ||
| Q9Y616 | Interleukin-1 receptor-associated kinase 3 | ||
| Q9Y618 | Nuclear receptor corepressor 2 | ||
| Q9Y639 | Neuroplastin |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Antimicrobial peptides | Drosophila melanogaster |
| Antimicrobial peptides | Rattus norvegicus |
| Antimicrobial peptides | Danio rerio |
| Antimicrobial peptides | Xenopus tropicalis |
| Antimicrobial peptides | Gallus gallus |
| Antimicrobial peptides | Homo sapiens |
| Antimicrobial peptides | Canis familiaris |
| Antimicrobial peptides | Dictyostelium discoideum |
| Antimicrobial peptides | Bos taurus |
| Antimicrobial peptides | Mus musculus |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 37028871 | Elucidating the role of N-acetylglucosamine in Group A Carbohydrate for the development of an effective glycoconjugate vaccine against Group A Streptococcus | Pitirollo O | 2023 Jul 01 |
|
| 37224467 | O-linked N-acetylglucosamine modification is essential for physiological adipose expansion induced by high-fat feeding | Nakamoto A | 2023 Jul 01 |
|
| 37137348 | Identification and functional characterisation of N-acetylglucosamine kinase from Helicoverpa armigera divulge its potential role in growth and development via UDP-GlcNAc salvage pathway | Das J | 2023 Jul 01 |
|
| 37028529 | Production of N-acetylglucosamine from carbon dioxide by engineering Cupriavidus necator H16 | Wang X | 2023 Jul |
|
| 36720854 | Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor | Duan J | 2023 Jan 31 |
|
| 36720859 | Molecular insights into the gating mechanisms of voltage-gated calcium channel CaV2.3 | Gao Y | 2023 Jan 31 |
|
| 36586406 | A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75 | Huo J | 2023 Jan 31 |
|
| 36511698 | Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates | Matsumoto K | 2023 Jan 31 |
|
| 36640338 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein | Saville JW | 2023 Jan 31 |
|
| 36776401 | Chemical biology tools to interrogate the roles of O-GlcNAc in immunity | Saha A | 2023 Jan 26 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Blocking O-linked GlcNAc cycling in Drosophila insulin-producing cells perturbs glucose-insulin homeostasis. |
|
J Biol Chem | 2010 Dec 3 | 20926386 |
| Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase. |
|
J Biol Chem | 2002 Jan 18 | 11788610 |
| Increased N-acetyl-beta-glucosaminidase activity in primary breast carcinomas corresponds to a decrease in N-acetylglucosamine containing proteins. |
|
Biochim Biophys Acta | 2001 Sep 28 | 11566258 |
| Clathrin assembly protein AP-3 is phosphorylated and glycosylated on the 50-kDa structural domain. |
|
J Biol Chem | 1994 Aug 19 | 8063760 |
