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Glycan Structure Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GlycoNAVI
- G49108TO
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT2 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT1 | UDP-Gal |
G49108TO
|
R |
G00055MO
|
R | |
| B3GALT5 | UDP-Gal |
G49108TO
|
R |
G00056MO
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| Q9Z0R4 | Intersectin-1 | ||
| Q9Z0R6 | Intersectin-2 | ||
| Q9Z0U1 | Tight junction protein 2 | ||
| Q9Z0V6 | Thioredoxin-dependent peroxide reductase, mitochondrial | ||
| Q9Z0Z7 | Krueppel-like factor 5 | ||
| Q9Z103 | Activity-dependent neuroprotector homeobox protein | ||
| Q9Z176 | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit delta | ||
| Q9Z180 | SET-binding protein | ||
| Q9Z188 | Dual specificity tyrosine-phosphorylation-regulated kinase 1B | ||
| Q9Z1A1 | TFG protein |
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Antimicrobial peptides | Drosophila melanogaster |
| Antimicrobial peptides | Rattus norvegicus |
| Antimicrobial peptides | Danio rerio |
| Antimicrobial peptides | Xenopus tropicalis |
| Antimicrobial peptides | Gallus gallus |
| Antimicrobial peptides | Homo sapiens |
| Antimicrobial peptides | Canis familiaris |
| Antimicrobial peptides | Dictyostelium discoideum |
| Antimicrobial peptides | Bos taurus |
| Antimicrobial peptides | Mus musculus |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 38658531 | A comprehensive synthetic library of poly-N-acetyl glucosamines enabled vaccine against lethal challenges of Staphylococcus aureus | Tan Z | 2024 Apr 24 |
|
| 38654003 | Protective effect of increased O-GlcNAc cycling against 6-OHDA induced Parkinson’s disease pathology | Kim DY | 2024 Apr 23 |
|
| 38647373 | Glycan-Reactive Innate-like B Cells and Developmental Checkpoints | New JS | 2024 Apr 22 |
|
| 38643446 | Lysinibacillus piscis sp. nov. isolated from the gut of mottled spinefoot Siganus fuscescens | Kanbe H | 2024 Apr 21 |
|
| 38503016 | Local thiamet-G delivery by a thermosensitive hydrogel confers ischemic cardiac repair via myeloid M2-like activation in a STAT6 O-GlcNAcylation-dependent manner | Zhou W | 2024 Apr 20 |
|
| 38641728 | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2 | Xia L | 2024 Apr 19 |
|
| 38632437 | ULK1-dependent phosphorylation of PKM2 antagonizes O-GlcNAcylation and regulates the Warburg effect in breast cancer | Zhou Z | 2024 Apr 17 |
|
| 38632262 | Malnutrition enteropathy in Zambian and Zimbabwean children with severe acute malnutrition: A multi-arm randomized phase II trial | Chandwe K | 2024 Apr 17 |
|
| 38627316 | MUC4 O-GlcNAcylation Regulates the Epithelial Phenotype in Conjunctival Epithelial Cells | Xiong WW | 2024 Apr 16 |
|
| 38622055 | Ngk1 kinase‐mediated N‐acetylglucosamine metabolism promotes <scp>UDP‐GlcNAc</scp> biosynthesis in Saccharomyces cerevisiae | Nishikawa A | 2024 Apr 15 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Blocking O-linked GlcNAc cycling in Drosophila insulin-producing cells perturbs glucose-insulin homeostasis. |
|
J Biol Chem | 2010 Dec 3 | 20926386 |
| Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase. |
|
J Biol Chem | 2002 Jan 18 | 11788610 |
| Increased N-acetyl-beta-glucosaminidase activity in primary breast carcinomas corresponds to a decrease in N-acetylglucosamine containing proteins. |
|
Biochim Biophys Acta | 2001 Sep 28 | 11566258 |
| Clathrin assembly protein AP-3 is phosphorylated and glycosylated on the 50-kDa structural domain. |
|
J Biol Chem | 1994 Aug 19 | 8063760 |
