G56478LD

Summary
GlyTouCan ID
G56478LD
IUPAC Condensed
Neu5Gc(a2-3)[GalNAc(b1-4)]Gal(b1-4)Glc(b1-
Motifs
N-Glycolyl-GM2
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
852.29
GlyGen
ChEBI
PubChem Compound
PubChem Substance
3D Structures
GlycoShape
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying 1 entry
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B4GALNT1 UDP-GalNAc
G75789AR
Cer
G56478LD
Cer
KEGG BRITE Database
KEGG ID
GlycoEpitope
Epitope ID
EP0052
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-glycolyl
5b:b-dgal-HEX-1:5
6s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:2o(4+1)5d
5:5d(2+1)6n
WURCS
WURCS=2.0/4,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCCO/3=O][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-4/a4-b1_b3-c2_b4-d1
Literature
Displaying all 9 entries
PubMed ID Title First Author Publication Date Source
7890749 Substrate specificity of beta 1,4-N-acetylgalactosaminyltransferase in vitro and in cDNA-transfected cells. GM2/GD2 synthase efficiently generates asialo-GM2 in certain cells Yamashiro S 1995 Mar 17
  • PubChem
8262898 Characterization of Ganglioside Expression in Human Melanoma Cells: Immunological and Biochemical Analysis1 Kawashima I 1993 Aug
  • GlyGen
  • GlycoEpitope
1726779 Concanavalin A-stimulated expression of gangliosides with GalNAc beta 1-4(NeuAc alpha 2-3)Gal beta structure in murine thymocytes Horikawa K 1991 Aug
  • GlyGen
  • GlycoEpitope
2159145 Human monoclonal antibody with dual GM2/GD2 specificity derived from an immunized melanoma patient Yamaguchi H 1990 May
  • GlyGen
  • GlycoEpitope
2111348 Northern hybridization analysis of VH gene expression in murine monoclonal antibodies directed to cancer-associated ganglioside antigens having various sialic acid linkages Zenita K 1990 Jun 01
  • GlyGen
  • GlycoEpitope
2153431 The abnormal occurrence and the differentiation-dependent distribution of N-acetyl and N-glycolyl species of the ganglioside GM2 in human germ cell tumors. A study with specific monoclonal antibodies Miyake M 1990 Feb 01
  • GlyGen
  • GlycoEpitope
3167861 Generation of two murine monoclonal antibodies that can discriminate N-glycolyl and N-acetyl neuraminic acid residues of GM2 gangliosides Miyake M 1988 Nov 01
  • GlyGen
  • GlycoEpitope
2449247 Monoclonal antibody directed to a Hanganutziu-Deicher active ganglioside, GM2 (NeuGc) Sanai Y 1988 Feb 19
  • GlyGen
  • GlycoEpitope
3731079 A murine monoclonal antibody detecting N-acetyl- and N-glycolyl-GM2: characterization of cell surface reactivity Natoli EJ 1986 Aug
  • GlyGen
  • GlycoEpitope
PubAnnotation
Displaying 1 entry
Title Authors Source Publication Date PubMed ID
Current relevance of incomplete synthesis and neo-synthesis for cancer-associated alteration of carbohydrate determinants--Hakomori's concepts revisited.
  • Kannagi R
  • Yin J
  • Miyazaki K
  • Izawa M
Biochim Biophys Acta 2008 Mar 17980710

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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