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GlyTouCan
Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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G64973KT
Summary
- GlyTouCan ID
-
G64973KT
- IUPAC Condensed
- Gal(b1-3)[Gal(b1-4)GlcNAc(b1-6)]GalNAc(a1-
- Motifs
- N-acetyllactosamine O-Glycan core 2 Type 2 LN
- Subsumption Level
- Fully-defined saccharide
- Monoisotopic Mass
- 748.27
3D Structures
G96017QA
G01759NM
Organisms
| Organisms | Evidence |
|---|---|
| Homo sapiens (human) | |
| Danio rerio (zebrafish) |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| ST3GAL4 | CMP-Neu5Ac |
G64973KT
|
O-glycan Synthesis |
G11457RF
|
O-glycan Synthesis | |
| FUT6 | GDP-Fuc |
G64973KT
|
O-glycan Synthesis |
G17752YB
|
O-glycan Synthesis | |
| B4GALT4 | UDP-Gal |
G00033MO
|
pNP |
G64973KT
|
pNP | |
| B4GALT1 | UDP-Gal |
G00033MO
|
O-glycan Synthesis |
G64973KT
|
O-glycan Synthesis | |
| A4GNT | UDP-GlcNAc |
G64973KT
|
[alpha]pNP |
G32910OR
|
[alpha]pNP |
KEGG BRITE Database
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| P13473 | Lysosome-associated membrane glycoprotein 2 | ||
| P14780 | Matrix metalloproteinase-9 | ||
| P15941 | Mucin-1 | ||
| P20239 | Zona pellucida sperm-binding protein 2 | ||
| P21754 | Zona pellucida sperm-binding protein 3 | ||
| P35253 | Envelope glycoprotein | ||
| P80195 | Glycosylation-dependent cell adhesion molecule 1 | ||
| P98088 | Mucin-5AC | ||
| Q02817 | Mucin-2 | ||
| Q14242 | P-selectin glycoprotein ligand 1 |
GlycomeAtlas
Tissues in which this glycan is expressed are highlighted in yellow.
- Danio rerio
Literature
- Tissue
-
- heart
- intestine
- testis
- Reference
- Yamakawa N et al. Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns. Nat Commun. 2018;9(1):4647. Published 2018 Nov 7. doi:10.1038/s41467-018-06950-3
- DOI
- 10.1038/s41467-018-06950-3
Localization sites organized by hierarchy by Uber-anatomy ontology (UBERON)
Sequence Descriptors
- GlycoCT
-
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl 3b:b-dgal-HEX-1:5 4b:b-dglc-HEX-1:5 5s:n-acetyl 6b:b-dgal-HEX-1:5 LIN 1:1d(2+1)2n 2:1o(3+1)3d 3:1o(6+1)4d 4:4d(2+1)5n 5:4o(4+1)6d
- WURCS
- WURCS=2.0/3,4,3/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5][a2122h-1b_1-5_2*NCC/3=O]/1-2-3-2/a3-b1_a6-c1_c4-d1
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 11323440 | Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans | Suzuki A | 2001 Jun 29 |
|
| 11123894 | O-Glycan Analysis of Natural Human Neutrophil Gelatinase B Using a Combination of Normal Phase- HPLC and Online Tandem Mass Spectrometry: Implications for the Domain Organization of the Enzyme | Mattu TS | 2000 Dec 01 |
|
| 10430883 | Expression cloning of a human alpha1, 4-N-acetylglucosaminyltransferase that forms GlcNAcalpha1-->4Galbeta-->R, a glycan specifically expressed in the gastric gland mucous cell-type mucin | Nakayama J | 1999 Aug 03 |
|
| 9492296 | Structural study of the O-linked sugar chains of human leukocyte tyrosine phosphatase CD45 | Furukawa K | 1998 Jan 15 |
|
| 9530955 | Purification and characterization of the MUC1 mucin-type glycoprotein, epitectin, from human urine: structures of the major oligosaccharide alditols | Bhavanandan VP | 1998 Jan |
|
| 9857011 | Synthesis of poly-N-acetyllactosamine in core 2 branched O-glycans. The requirement of novel beta-1,4-galactosyltransferase IV and beta-1,3-n-acetylglucosaminyltransferase | Ujita M | 1998 Dec 25 |
|
| 9180155 | Isolation and characterization of ovarian cancer antigen CA 125 using a new monoclonal antibody (VK-8): identification as a mucin-type molecule | Lloyd KO | 1997 May 29 |
|
| 9449027 | Carbohydrate and peptide structure of the alpha- and beta-subunits of human chorionic gonadotropin from normal and aberrant pregnancy and choriocarcinoma | Elliott MM | 1997 Aug |
|
| 8702529 | Structures of the O-Glycans on P-selectin Glycoprotein Ligand-1 from HL-60 Cells | Wilkins PP | 1996 Aug 02 |
|
| 8323299 | Assignment of O-Glycan Attachment Sites to the Hinge-like Regions of Human Lysosomal Membrane Glycoproteins Lamp-1 and Lamp-2 | Carlsson SR | 1993 Jul |
|
