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GlyTouCan
Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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G64973KT
Summary
- GlyTouCan ID
-
G64973KT
- IUPAC Condensed
- Gal(b1-3)[Gal(b1-4)GlcNAc(b1-6)]GalNAc(a1-
- Motifs
- N-acetyllactosamine O-Glycan core 2 Type 2 LN
- Subsumption Level
- Fully-defined saccharide
- Monoisotopic Mass
- 748.27
3D Structures
G96017QA
G01759NM
Organisms
| Organisms | Evidence |
|---|---|
| synthetic construct | |
| Ovis aries (sheep) | |
| Mus musculus (house mouse) | |
| Bos taurus (domestic cattle) | |
| Rattus norvegicus (Norway rat) |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| ST3GAL4 | CMP-Neu5Ac |
G64973KT
|
O-glycan Synthesis |
G11457RF
|
O-glycan Synthesis | |
| FUT6 | GDP-Fuc |
G64973KT
|
O-glycan Synthesis |
G17752YB
|
O-glycan Synthesis | |
| B4GALT4 | UDP-Gal |
G00033MO
|
pNP |
G64973KT
|
pNP | |
| B4GALT1 | UDP-Gal |
G00033MO
|
O-glycan Synthesis |
G64973KT
|
O-glycan Synthesis | |
| A4GNT | UDP-GlcNAc |
G64973KT
|
[alpha]pNP |
G32910OR
|
[alpha]pNP |
KEGG BRITE Database
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| O02197 | Circulating cathodic antigen | ||
| P01190 | Pro-opiomelanocortin | ||
| P01215 | Glycoprotein hormones alpha chain | ||
| P01876 | Immunoglobulin heavy constant alpha 1 | ||
| P02668 | Kappa-casein | ||
| P07498 | Kappa-casein | ||
| P08575 | Receptor-type tyrosine-protein phosphatase C | ||
| P0DN86 | Choriogonadotropin subunit beta 3 | ||
| P10761 | Zona pellucida sperm-binding protein 3 | ||
| P11279 | Lysosome-associated membrane glycoprotein 1 |
GlycomeAtlas
Tissues in which this glycan is expressed are highlighted in yellow.
- Danio rerio
Literature
- Tissue
-
- heart
- intestine
- testis
- Reference
- Yamakawa N et al. Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns. Nat Commun. 2018;9(1):4647. Published 2018 Nov 7. doi:10.1038/s41467-018-06950-3
- DOI
- 10.1038/s41467-018-06950-3
Localization sites organized by hierarchy by Uber-anatomy ontology (UBERON)
Sequence Descriptors
- GlycoCT
-
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl 3b:b-dgal-HEX-1:5 4b:b-dglc-HEX-1:5 5s:n-acetyl 6b:b-dgal-HEX-1:5 LIN 1:1d(2+1)2n 2:1o(3+1)3d 3:1o(6+1)4d 4:4d(2+1)5n 5:4o(4+1)6d
- WURCS
- WURCS=2.0/3,4,3/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5][a2122h-1b_1-5_2*NCC/3=O]/1-2-3-2/a3-b1_a6-c1_c4-d1
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 1627559 | The broad diversity of neutral and sialylated oligosaccharides derived from human salivary mucins | Klein A | 1992 Jul 7 |
|
| 1374031 | The carbohydrate chains of the beta subunit of human chorionic gonadotropin produced by the choriocarcinoma cell line BeWo. Novel O-linked and novel bisecting-GlcNAc-containing N-linked carbohydrates | Hard K | 1992 Apr 15 |
|
| 1820200 | Site-specific N-glycosylation of human chorionic gonadotrophin--structural analysis of glycopeptides by one- and two-dimensional 1H NMR spectroscopy | Weisshaar G | 1991 Sep |
|
| 1726196 | Characterisation of minor tetra- to hepta-saccharides O-linked to human meconium glycoproteins by t.l.c.-m.s. microsequencing of neoglycolipid derivatives in conjunction with conventional m.s. and 1H-n.m.r. spectroscopy | Lawson AM | 1991 Dec 16 |
|
| 1967025 | Altered glycosylation of human chorionic gonadotropin decreases its hormonal activity as determined by cyclic-adenosine 3',5'-monophosphate production in MA-10 cells | Amano J | 1990 Sep |
|
| 2737211 | Primary structure of twenty three neutral and monosialylated oligosaccharides O-glycosidically linked to the human secretory immunoglobulin A hinge region determined by a combination of permethylation analysis and 400-MHz 1H-NMR spectroscopy | PIERCE‐CRÉTEL A | 1989 Jun 15 |
|
| 2731547 | Structures of O-glycosidically linked oligosaccharides isolated from human meconium glycoproteins | Capon C | 1989 Jun 1 |
|
| 3335536 | Comparative study of the mucin-type sugar chains of human chorionic gonadotropin present in the urine of patients with trophoblastic diseases and healthy pregnant women | Amano J | 1988 Jan 25 |
|
| 3342257 | Chemical structure of neutral sugar chains isolated from human mature milk kappa-casein | Saito T | 1988 Feb 17 |
|
| 3345749 | Primary structure of neutral oligosaccharides derived from respiratory-mucus glycoproteins of a patient suffering from bronchiectasis, determined by combination of 500-MHz 1H-NMR spectroscopy and quantitative sugar analysis. 1. Structure of 16 oligosaccharides having the Gal beta(1----3)GalNAc-ol core (type 1) or the Gal beta(1----3)[GlcNAc beta(1----6)]GalNac-ol core (type 2) | Klein A | 1988 Feb 1 |
|
