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G91237TK

Summary

GlyTouCan ID: G91237TK
IUPAC Condensed: Neu5Ac(a2-3)Gal(b1-4)Glc(b1-
Motifs: GM3
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 633.21

External Links

GlyGen

G91237TK

ChEBI

59226

PubChem Compound

5288424

PubChem Substance

252278045

3D Structures

GLYCAM: Neup5Aca2-3DGalpb1-4DGlcpb1-OH

GlycoShape

G91237TK

Displaying 1 entry
Archetype	α	β
G40764VP	G92323ZH	G91237TK

Organisms

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Organisms	Evidence
Oryctolagus cuniculus (rabbit)	GlyTouCan(glycome-db)
Ovis aries (sheep)	GlyTouCan(glycome-db)
Chionodraco myersi (Myers' icefish)	GlyTouCan(glycome-db)
Gallus gallus (chicken)	GlyTouCan(glycome-db)
Felis catus (domestic cat)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Otomorpha [inference]

Ostariophysi [inference]

Otophysi [inference]

Cypriniphysae [inference]

Cypriniformes (carps and others) [inference]

Cyprinoidei [inference]

Leuciscidae [inference]

Leuciscinae [inference]

Scardinius [inference]

Scardinius erythrophthalmus (rudd)

Cyprinidae [inference]

Cyprininae [inference]

Cyprinus [inference]

Cyprinus carpio (common carp)

Carassius [inference]

Carassius auratus (goldfish)

Euteleosteomorpha [inference]

Protacanthopterygii [inference]

Salmoniformes (salmons and trouts) [inference]

Salmonidae (salmonids) [inference]

Salmoninae (trouts, salmons & chars) [inference]

Oncorhynchus [inference]

Oncorhynchus mykiss (rainbow trout)

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Euacanthomorphacea [inference]

Percomorphaceae [inference]

Ovalentaria [inference]

Cichlomorphae [inference]

Cichliformes (cichlids and convict blennies) [inference]

Cichlidae (cichlids) [inference]

African cichlids [inference]

Pseudocrenilabrinae [inference]

Oreochromini [inference]

Oreochromis [inference]

Oreochromis mossambicus (Mozambique tilapia)

Eupercaria [inference]

Perciformes (perches and others) [inference]

Notothenioidei [inference]

Nototheniidae (Antarctic cods) [inference]

Trematomus [inference]

Trematomus lepidorhinus (slender scalyhead)

Channichthyidae (crocodile icefishes) [inference]

Chionodraco [inference]

Chionodraco myersi (Myers' icefish)

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus [inference]

Gadus morhua (Atlantic cod)

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amphibia (amphibians) [inference]

Batrachia [inference]

Anura (frogs and toads) [inference]

Pipoidea [inference]

Pipidae (tongueless frogs) [inference]

Xenopodinae [inference]

Xenopus

Xenopus [inference]

Xenopus laevis (African clawed frog)

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Platyrrhini (New World monkeys)

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Papio (baboons) [inference]

Papio hamadryas (hamadryas baboon)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Glires (Rodents and rabbits) [inference]

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Rodentia (rodent) [inference]

Hystricomorpha (guinea pigs and others) [inference]

Caviidae (cavies) [inference]

Cavia (guinea pigs) [inference]

Cavia porcellus (domestic guinea pig)

Chinchillidae (chinchillas)

Chinchilla

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Rattus

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Cricetidae [inference]

Cricetinae (hamsters)

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Phodopus [inference]

Phodopus sungorus

Laurasiatheria [inference]

Carnivora (carnivores) [inference]

Feliformia [inference]

Felidae (cat family) [inference]

Felinae [inference]

Felis [inference]

Felis catus (domestic cat)

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Caprinae [inference]

Ovis [inference]

Ovis aries (sheep)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls) [inference]

Phasianidae (turkeys) [inference]

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Chondrichthyes (cartilaginous fishes) [inference]

Elasmobranchii (elasmobranchs) [inference]

Batoidea (rays) [inference]

Rajiformes (skates) [inference]

Rajidae (hardnose skates)

Leucoraja [inference]

Leucoraja erinacea (little skate)

Torpediniformes [inference]

Narcinidae (numbfishes) [inference]

Discopyge [inference]

Discopyge tschudii (apron ray)

Torpedinidae (electric rays) [inference]

Torpedo [inference]

Torpedo marmorata (marbled electric ray)

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

Campylobacterota [inference]

Epsilonproteobacteria [inference]

Campylobacterales [inference]

Campylobacteraceae [inference]

Campylobacter [inference]

Campylobacter jejuni

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
B4GALNT1	UDP-GalNAc	G91237TK	Cer	G79389NT	Cer	1601877

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA6	CMP-Neu5Ac	G91237TK		G98544DH		11980897
ST8SIA3	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	7782326 8910600
ST3GAL3	CMP-Neu5Ac	G84224TW	free	G91237TK	free	8288606
ST8SIA1	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	8195250 8910600
ST3GAL5	CMP-Neu5Ac	G84224TW	ceramide	G91237TK	ceramide	9822625

Displaying entries **1 - 5** of 8 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST3GAL6	CMP-Neu5Ac	G91237TK	ceramide	10206952
ST8SIA5	CMP-Neu5Ac	G91237TK	Cer	8910600 9199191
ST6GAL1	CMP-Neu5Ac	G91237TK	ceramide	12235148
ST8SIA2	CMP-Neu5Ac	G91237TK	Cer	7782326
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	16120058

KEGG BRITE Database

KEGG ID

G00108

Enzyme

References

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R06004	3.2.1.52	G79389NT	G91237TK
R05937	2.4.3.9	G84224TW	G91237TK
R05940	2.4.3.8	G91237TK	G98544DH
R05939	2.4.1.92	G91237TK	G79389NT

GlycoEpitope

Epitope ID: EP0053

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n

WURCS

WURCS=2.0/3,3,2/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3/a4-b1_b3-c2

Literature

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PubMed ID	Title	First Author	Publication Date	Source
2231724	2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES	Wright CS	1990 Oct 15	PubChem
2908845	Two human monoclonal antibodies reacting with the major gangliosides of human melanomas and comparison with corresponding mouse monoclonal antibodies	Furukawa K	1989 Jan 01	GlyGen GlycoEpitope
3167827	An IgG3 monoclonal antibody established after immunization with GM3 lactone: immunochemical specificity and inhibition of melanoma cell growth in vitro and in vivo	Dohi T	1988 Oct 15	GlyGen GlycoEpitope
3031684	Cell-surface antigens of melanoma recognized by human monoclonal antibodies	Yamaguchi H	1987 Apr	GlyGen GlycoEpitope
2414279	Syngeneic monoclonal antibody against melanoma antigen with interspecies cross-reactivity recognizes GM3, a prominent ganglioside of B16 melanoma	Hirabayashi Y	1985 Oct 25	GlyGen GlycoEpitope

PubAnnotation

Displaying entries **6 - 10** of 10 in total

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Title	Authors	Source	Publication Date	PubMed ID
Gangliosides of human acute leukemia cells.	Westrick MA Lee WM Goff B Macher BA	Biochim Biophys Acta	1983 Jan 7	6572071
Lipid composition and molecular species of sialic acids of a mouse cell line (JLS-V9) and its ouabain-resistant mutant.	Niimura Y Ishizuka I	Biochim Biophys Acta	1981 Jan 26	6260211
Action of ortho- and paramyxovirus neuraminidase on gangliosides. Hydrolysis of ganglioside GM1 by Sendai virus neuraminidase.	Suzuki Y Morioka T Matsumoto M	Biochim Biophys Acta	1980 Sep 8	6257300
Ganglioside biosynthesis in rat liver: alteration of sialyltransferase activities by nucleotides.	Eppler CM Morré DJ Keenan TW	Biochim Biophys Acta	1980 Aug 11	7407217
Tissue distribution of EDTA encapsulated within liposomes containing glycolipids or brain phospholipids.	Jonah MM Cerny EA Rahman YE	Biochim Biophys Acta	1978 Jul 3	96869

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements