G79389NT

Summary
GlyTouCan ID
G79389NT
IUPAC Condensed
Neu5Ac(a2-3)[GalNAc(b1-4)]Gal(b1-4)Glc(b1-
Motifs
GM2
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
836.29
GlyGen
ChEBI
PubChem Compound
PubChem Substance
3D Structures
GlycoShape
G79389NT
Displaying 1 entry
Archetype α β
G65156XZ
G04658QB
G79389NT
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 3 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALT4 UDP-Gal
G79389NT
Cer
G48558GR
Cer
B4GALNT2 UDP-GalNAc
G91237TK
G79389NT
B4GALNT1 UDP-GalNAc
G91237TK
Cer
G79389NT
Cer
Displaying all 3 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALT4 UDP-Gal
G79389NT
Cer
G48558GR
Cer
B4GALNT2 UDP-GalNAc
G91237TK
G79389NT
B4GALNT1 UDP-GalNAc
G91237TK
Cer
G79389NT
Cer
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST3GAL6 CMP-Neu5Ac
G79389NT
ceramide
B4GALT3 UDP-Gal
G79389NT
Cer
B3GALT2 UDP-Gal
G79389NT
Cer
B3GALT1 UDP-Gal
G79389NT
Cer
B3GNT6 UDP-GlcNAc
G79389NT
GlycoEpitope
Epitope ID
EP0051
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:b-dgal-HEX-1:5
6s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:2o(4+1)5d
5:5d(2+1)6n
WURCS
WURCS=2.0/4,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-4/a4-b1_b3-c2_b4-d1
Literature
Displaying entries 1 - 10 of 38 in total
PubMed ID Title First Author Publication Date Source
25855729 The Greater Affinity of JC Polyomavirus Capsid for α2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity Ströh LJ 2015 Jun 15
  • PubChem
26715202 Complement Factor H and Simian Virus 40 bind the GM1 ganglioside in distinct conformations Blaum BS 2015 Dec 28
  • PubChem
23236285 The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus Reiss K 2012 Dec 06
  • PubChem
16024647 Characterization of a proapoptotic antiganglioside GM2 monoclonal antibody and evaluation of its therapeutic effect on melanoma and small cell lung carcinoma xenografts Retter MW 2005 Jul 15
  • GlyGen
  • GlycoEpitope
15464996 Gangliosides of organ-confined versus metastatic androgen-receptor-negative prostate cancer Ravindranath MH 2004 Nov 05
  • GlyGen
  • GlycoEpitope
12678917 Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain Montiel MD 2003 Jul 15
  • PubChem
12393027 Immunohistochemical detection of hepatic GM1 and GM2 gangliosides in streptozotocin-induced diabetic rats Abregu AV 2002 Nov
  • GlyGen
  • GlycoEpitope
11821425 Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans Iwai T 2002 Apr 12
  • PubChem
11358851 Ganglioside G(D2) in small cell lung cancer cell lines: enhancement of cell proliferation and mediation of apoptosis Yoshida S 2001 May 15
  • GlyGen
  • GlycoEpitope
11903928 The glioma-associated gangliosides 3'-isoLM1, GD3 and GM2 show selective area expression in human glioblastoma xenografts in nude rat brains Hedberg KM 2001 Dec
  • GlyGen
  • GlycoEpitope
PubAnnotation
Displaying entries 1 - 5 of 10 in total
Title Authors Source Publication Date PubMed ID
Ganglioside-specific binding protein on rat brain membranes.
  • Tiemeyer M
  • Yasuda Y
  • Schnaar RL
J Biol Chem 1989 Jan 25 2912979
Monoclonal antibody detects monosialogangliosides having a sialic acid alpha 2----3-galactosyl residue.
  • Tai T
  • Sze L
  • Kawashima I
  • Saxton RE
  • Irie RF
J Biol Chem 1987 May 15 3571288
Monoclonal antibody Leo Mel 3, which inhibits killing of human melanoma cells by anomalous killer cells, binds to a sugar sequence in GD2 (II3(NeuAc)2-GgOse3Cer) and several other gangliosides.
  • Fukuta S
  • Werkmeister JA
  • Burns GF
  • Ginsburg V
  • Magnani JL
J Biol Chem 1987 Apr 5 2435716
Mouse liver gangliosides.
  • Suzuki M
  • Nakamura K
  • Hashimoto Y
  • Suzuki A
  • Yamakawa T
Carbohydr Res 1986 Aug 15 3768889
Preparation and enzymatic degradation of monosulfogangliotriaosylceramide.
  • Ishizuka I
  • Nagai K
  • Kawaguchi K
  • Tadano-Aritomi K
  • Toida T
  • Hirabayashi Y
  • Li YT
  • Li SC
J Biol Chem 1985 Sep 15 3928630

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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