G48558GR

Summary
GlyTouCan ID
G48558GR
IUPAC Condensed
Neu5Ac(a2-3)[Gal(b1-3)GalNAc(b1-4)]Gal(b1-4)Glc(b1-
Motifs
GM1
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
998.34
GlyGen
ChEBI
PubChem Compound
PubChem Substance
3D Structures
GlycoShape
G48558GR
Displaying 1 entry
Archetype α β
G41876BL
G64489RR
G48558GR
Organisms
GlycoGene Database (GGDB)
Displaying 1 entry
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALT4 UDP-Gal
G79389NT
Cer
G48558GR
Cer
Displaying all 3 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST3GAL2 CMP-Neu5Ac
G48558GR
Cer
G46677TE
Cer
ST3GAL1 CMP-Neu5Ac
G48558GR
ceramide
G46677TE
ceramide
B3GALT4 UDP-Gal
G79389NT
Cer
G48558GR
Cer
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST8SIA6 CMP-Neu5Ac
G48558GR
Cer
ST6GAL1 CMP-Neu5Ac
G48558GR
ceramide
ST6GALNAC2 CMP-Neu5Ac
G48558GR
ceramide
ST6GALNAC4 CMP-Neu5Ac
G48558GR
ceramide
ST3GAL6 CMP-Neu5Ac
G48558GR
ceramide
KEGG BRITE Database
GlycoEpitope
Epitope ID
EP0050
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:b-dgal-HEX-1:5
6s:n-acetyl
7b:b-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:2o(4+1)5d
5:5d(2+1)6n
6:5o(3+1)7d
WURCS
WURCS=2.0/4,5,4/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-4-2/a4-b1_b3-c2_b4-d1_d3-e1
Literature
Displaying entries 1 - 10 of 63 in total
PubMed ID Title First Author Publication Date Source
33065002 Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly Wang L 2020 Nov 05
  • PubChem
32325905 GM1 Oligosaccharide Crosses the Human Blood–Brain Barrier In Vitro by a Paracellular Route Di Biase E 2020 Apr 19
  • PubChem
30911934 The Neuroprotective Role of the GM1 Oligosaccharide, II3Neu5Ac-Gg4, in Neuroblastoma Cells Chiricozzi E 2019 Mar 26
  • PubChem
31852959 Parkinson’s disease recovery by GM1 oligosaccharide treatment in the B4galnt1+/− mouse model Chiricozzi E 2019 Dec 18
  • PubChem
28179425 Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases Han Y 2017 Mar 24
  • PubChem
28645943 The structure of the tetanus toxin reveals <scp>pH</scp>‐mediated domain dynamics Masuyer G 2017 Jun 23
  • PubChem
26760438 Fighting Cholera One-on-One: The Development and Efficacy of Multivalent Cholera-Toxin-Binding Molecules Zuilhof H 2016 Jan 13
  • PubChem
25855729 The Greater Affinity of JC Polyomavirus Capsid for α2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity Ströh LJ 2015 Jun 15
  • PubChem
26715202 Complement Factor H and Simian Virus 40 bind the GM1 ganglioside in distinct conformations Blaum BS 2015 Dec 28
  • PubChem
26302170 Trichodysplasia spinulosa-Associated Polyomavirus Uses a Displaced Binding Site on VP1 to Engage Sialylated Glycolipids Ströh LJ 2015 Aug 24
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
Activators of spleen glucocerebrosidase from controls and patients with various forms of Gaucher's disease.
  • Basu A
  • Glew RH
  • Daniels LB
  • Clark LS
J Biol Chem 1984 Feb 10 6693432
Galactose oxidase action on GM1 ganglioside in micellar and vesicular dispersions.
  • Masserini M
  • Sonnino S
  • Ghidoni R
  • Chigorno V
  • Tettamanti G
Biochim Biophys Acta 1982 Jun 14 7104327
Structure analysis of the major oligosaccharides accumulating in canine GM1 gangliosidosis liver.
  • Warner TG
  • O'Brien JS
J Biol Chem 1982 Jan 10 6796586
Action of ortho- and paramyxovirus neuraminidase on gangliosides. Hydrolysis of ganglioside GM1 by Sendai virus neuraminidase.
  • Suzuki Y
  • Morioka T
  • Matsumoto M
Biochim Biophys Acta 1980 Sep 8 6257300
Ganglioside biosynthesis in rat liver: alteration of sialyltransferase activities by nucleotides.
  • Eppler CM
  • Morré DJ
  • Keenan TW
Biochim Biophys Acta 1980 Aug 11 7407217

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