G48558GR

Summary
GlyTouCan ID
G48558GR
IUPAC Condensed
Neu5Ac(a2-3)[Gal(b1-3)GalNAc(b1-4)]Gal(b1-4)Glc(b1-
Motifs
GM1
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
998.34
GlyGen
ChEBI
PubChem Compound
PubChem Substance
3D Structures
GlycoShape
G48558GR
Displaying 1 entry
Archetype α β
G41876BL
G64489RR
G48558GR
Organisms
GlycoGene Database (GGDB)
Displaying 1 entry
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALT4 UDP-Gal
G79389NT
Cer
G48558GR
Cer
Displaying all 3 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST3GAL2 CMP-Neu5Ac
G48558GR
Cer
G46677TE
Cer
ST3GAL1 CMP-Neu5Ac
G48558GR
ceramide
G46677TE
ceramide
B3GALT4 UDP-Gal
G79389NT
Cer
G48558GR
Cer
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST8SIA6 CMP-Neu5Ac
G48558GR
Cer
ST6GAL1 CMP-Neu5Ac
G48558GR
ceramide
ST6GALNAC2 CMP-Neu5Ac
G48558GR
ceramide
ST6GALNAC4 CMP-Neu5Ac
G48558GR
ceramide
ST3GAL6 CMP-Neu5Ac
G48558GR
ceramide
KEGG BRITE Database
GlycoEpitope
Epitope ID
EP0050
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:b-dgal-HEX-1:5
6s:n-acetyl
7b:b-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:2o(4+1)5d
5:5d(2+1)6n
6:5o(3+1)7d
WURCS
WURCS=2.0/4,5,4/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-4-2/a4-b1_b3-c2_b4-d1_d3-e1
Literature
Displaying entries 11 - 20 of 63 in total
PubMed ID Title First Author Publication Date Source
24095060 EcxAB Is a Founding Member of a New Family of Metalloprotease AB5 Toxins with a Hybrid Cholera-like B Subunit Ng NM 2013 Nov 05
  • PubChem
21949831 Structural Basis for Distinct Binding Properties of the Human Galectins to Thomsen-Friedenreich Antigen Bian C 2011 Sep 20
  • PubChem
21168418 Crystal Structures Exploring the Origins of the Broader Specificity of Escherichia coli Heat-Labile Enterotoxin Compared to Cholera Toxin Holmner A 2011 Feb 25
  • PubChem
20530247 Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen‐Friedenreich antigen Feng L 2010 Jun 07
  • PubChem
19665695 Carbohydrate-based anti-adhesive inhibition of Vibrio cholerae toxin binding to GM1-OS immobilized into artificial planar lipid membranes Sinclair HR 2009 Oct 12
  • PubChem
19404395 Cold Induces Micro- and Nano-Scale Reorganization of Lipid Raft Markers at Mounds of T-Cell Membrane Fluctuations Chen Y 2009 Apr 30
  • PubChem
18593944 GM1 Expression of Non-Hodgkin's Lymphoma Determines Susceptibility to Rituximab Treatment Meyer zum Büschenfelde C 2008 Jul 01
  • PubChem
18274892 A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH Yoshikawa T 2008 Feb 15
  • PubChem
18353982 Structural basis of GM1 ganglioside recognition by simian virus 40 Neu U 2008 Apr 01
  • PubChem
17855742 Sulfatide binding properties of murine and human antiganglioside antibodies Townson K 2007 Aug 17
  • GlyGen
  • GlycoEpitope
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
Activators of spleen glucocerebrosidase from controls and patients with various forms of Gaucher's disease.
  • Basu A
  • Glew RH
  • Daniels LB
  • Clark LS
J Biol Chem 1984 Feb 10 6693432
Galactose oxidase action on GM1 ganglioside in micellar and vesicular dispersions.
  • Masserini M
  • Sonnino S
  • Ghidoni R
  • Chigorno V
  • Tettamanti G
Biochim Biophys Acta 1982 Jun 14 7104327
Structure analysis of the major oligosaccharides accumulating in canine GM1 gangliosidosis liver.
  • Warner TG
  • O'Brien JS
J Biol Chem 1982 Jan 10 6796586
Action of ortho- and paramyxovirus neuraminidase on gangliosides. Hydrolysis of ganglioside GM1 by Sendai virus neuraminidase.
  • Suzuki Y
  • Morioka T
  • Matsumoto M
Biochim Biophys Acta 1980 Sep 8 6257300
Ganglioside biosynthesis in rat liver: alteration of sialyltransferase activities by nucleotides.
  • Eppler CM
  • Morré DJ
  • Keenan TW
Biochim Biophys Acta 1980 Aug 11 7407217

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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