GlyCosmos Portal

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G91237TK

Summary

GlyTouCan ID: G91237TK
IUPAC Condensed: Neu5Ac(a2-3)Gal(b1-4)Glc(b1-
Motifs: GM3
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 633.21

External Links

GlyGen

G91237TK

ChEBI

59226

PubChem Compound

5288424

PubChem Substance

252278045

3D Structures

GLYCAM: Neup5Aca2-3DGalpb1-4DGlcpb1-OH

GlycoShape

G91237TK

Displaying 1 entry
Archetype	α	β
G40764VP	G92323ZH	G91237TK

Organisms

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Organisms	Evidence
Felis catus (domestic cat)	GlyTouCan(glycome-db)
Ovis aries (sheep)	GlyTouCan(glycome-db)
Cricetulus griseus (Chinese hamster)	GlyTouCan(glycome-db)
Carassius auratus (goldfish)	GlyTouCan(glycome-db)
Torpedo marmorata (marbled electric ray)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Chondrichthyes (cartilaginous fishes) [inference]

Elasmobranchii (elasmobranchs) [inference]

Batoidea (rays) [inference]

Rajiformes (skates) [inference]

Rajidae (hardnose skates)

Leucoraja [inference]

Leucoraja erinacea (little skate)

Torpediniformes [inference]

Torpedinidae (electric rays) [inference]

Torpedo [inference]

Torpedo marmorata (marbled electric ray)

Narcinidae (numbfishes) [inference]

Discopyge [inference]

Discopyge tschudii (apron ray)

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Protacanthopterygii [inference]

Salmoniformes (salmons and trouts) [inference]

Salmonidae (salmonids) [inference]

Salmoninae (trouts, salmons & chars) [inference]

Oncorhynchus [inference]

Oncorhynchus mykiss (rainbow trout)

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Euacanthomorphacea [inference]

Percomorphaceae [inference]

Eupercaria [inference]

Perciformes (perches and others) [inference]

Notothenioidei [inference]

Channichthyidae (crocodile icefishes) [inference]

Chionodraco [inference]

Chionodraco myersi (Myers' icefish)

Nototheniidae (Antarctic cods) [inference]

Trematomus [inference]

Trematomus lepidorhinus (slender scalyhead)

Ovalentaria [inference]

Cichlomorphae [inference]

Cichliformes (cichlids and convict blennies) [inference]

Cichlidae (cichlids) [inference]

African cichlids [inference]

Pseudocrenilabrinae [inference]

Oreochromini [inference]

Oreochromis [inference]

Oreochromis mossambicus (Mozambique tilapia)

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus [inference]

Gadus morhua (Atlantic cod)

Otomorpha [inference]

Ostariophysi [inference]

Otophysi [inference]

Cypriniphysae [inference]

Cypriniformes (carps and others) [inference]

Cyprinoidei [inference]

Cyprinidae [inference]

Cyprininae [inference]

Carassius [inference]

Carassius auratus (goldfish)

Cyprinus [inference]

Cyprinus carpio (common carp)

Leuciscidae [inference]

Leuciscinae [inference]

Scardinius [inference]

Scardinius erythrophthalmus (rudd)

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Ovis aries (sheep)

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Feliformia [inference]

Felidae (cat family) [inference]

Felinae [inference]

Felis [inference]

Felis catus (domestic cat)

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Cricetidae [inference]

Cricetinae (hamsters)

Phodopus [inference]

Phodopus sungorus

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Hystricomorpha (guinea pigs and others) [inference]

Chinchillidae (chinchillas)

Chinchilla

Caviidae (cavies) [inference]

Cavia (guinea pigs) [inference]

Cavia porcellus (domestic guinea pig)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Platyrrhini (New World monkeys)

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Papio (baboons) [inference]

Papio hamadryas (hamadryas baboon)

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls) [inference]

Phasianidae (turkeys) [inference]

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Amphibia (amphibians) [inference]

Batrachia [inference]

Anura (frogs and toads) [inference]

Pipoidea [inference]

Pipidae (tongueless frogs) [inference]

Xenopodinae [inference]

Xenopus

Xenopus [inference]

Xenopus laevis (African clawed frog)

Bacteria (eubacteria) [inference]

Campylobacterota [inference]

Epsilonproteobacteria [inference]

Campylobacterales [inference]

Campylobacteraceae [inference]

Campylobacter [inference]

Campylobacter jejuni

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

GlycoGene Database (GGDB)

Displaying entries **1 - 5** of 6 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA1	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	8195250
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	11980897
ST8SIA3	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	7782326
ST3GAL5	CMP-Neu5Ac	G84224TW	ceramide	G91237TK	ceramide	9822625
B4GALNT2	UDP-GalNAc	G91237TK		G79389NT		12678917

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA1	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	8195250 8910600
ST3GAL3	CMP-Neu5Ac	G84224TW	free	G91237TK	free	8288606
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	11980897
ST8SIA3	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	7782326 8910600
ST8SIA6	CMP-Neu5Ac	G91237TK		G98544DH		11980897

Displaying entries **1 - 5** of 8 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST8SIA2	CMP-Neu5Ac	G91237TK	Cer	7782326
ST8SIA5	CMP-Neu5Ac	G91237TK	Cer	8910600 9199191
ST3GAL6	CMP-Neu5Ac	G91237TK	ceramide	10206952
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	16120058
ST6GAL1	CMP-Neu5Ac	G91237TK	ceramide	12235148

KEGG BRITE Database

KEGG ID

G00108

Enzyme

References

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05937	2.4.3.9	G84224TW	G91237TK
R05939	2.4.1.92	G91237TK	G79389NT
R05940	2.4.3.8	G91237TK	G98544DH
R06004	3.2.1.52	G79389NT	G91237TK

GlycoEpitope

Epitope ID: EP0053

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n

WURCS

WURCS=2.0/3,3,2/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3/a4-b1_b3-c2

Literature

Displaying entries **21 - 30** of 55 in total

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PubMed ID	Title	First Author	Publication Date	Source
19124471	Enhancing the Receptor Affinity of the Sialic Acid-binding Domain of Vibrio cholerae Sialidase through Multivalency	Connaris H	2009 Mar 13	PubChem
18022638	Structural Implications of Siglec-5-Mediated Sialoglycan Recognition	Zhuravleva MA	2008 Jan 11	PubChem
17329247	Structural and Mechanistic Analyses of endo-Glycoceramidase II, a Membrane-associated Family 5 Glycosidase in the Apo and GM3 Ganglioside-bound Forms	Caines MEC	2007 May 11	PubChem
16621820	Mutation of waaC, encoding heptosyltransferase I in Campylobacter jejuni 81-176, affects the structure of both lipooligosaccharide and capsular carbohydrate	Kanipes MI	2006 May	BCSDB GlyGen
16120058	Molecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteins	Teintenier-Lelièvre M	2005 Dec 06	PubChem
16051274	Structural Basis of a Fungal Galectin from Agrocybe cylindracea for Recognizing Sialoconjugate	Ban M	2005 Aug 26	PubChem
12678917	Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain	Montiel MD	2003 Jul 15	PubChem
12235148	Characterization of the second type of human beta-galactoside alpha 2,6-sialyltransferase (ST6Gal II), which sialylates Galbeta 1,4GlcNAc structures on oligosaccharides preferentially. Genomic analysis of human sialyltransferase genes	Takashima S	2002 Nov 29	PubChem
11980897	Molecular cloning and expression of a sixth type of alpha 2,8-sialyltransferase (ST8Sia VI) that sialylates O-glycans	Takashima S	2002 Jul 05	PubChem
10747930	An Unusual Carbohydrate Binding Site Revealed by the Structures of Two Maackia amurensis Lectins Complexed with Sialic Acid-containing Oligosaccharides	Imberty A	2000 Jun 09	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Gangliosides of human acute leukemia cells.	Westrick MA Lee WM Goff B Macher BA	Biochim Biophys Acta	1983 Jan 7	6572071
Lipid composition and molecular species of sialic acids of a mouse cell line (JLS-V9) and its ouabain-resistant mutant.	Niimura Y Ishizuka I	Biochim Biophys Acta	1981 Jan 26	6260211
Action of ortho- and paramyxovirus neuraminidase on gangliosides. Hydrolysis of ganglioside GM1 by Sendai virus neuraminidase.	Suzuki Y Morioka T Matsumoto M	Biochim Biophys Acta	1980 Sep 8	6257300
Ganglioside biosynthesis in rat liver: alteration of sialyltransferase activities by nucleotides.	Eppler CM Morré DJ Keenan TW	Biochim Biophys Acta	1980 Aug 11	7407217
Tissue distribution of EDTA encapsulated within liposomes containing glycolipids or brain phospholipids.	Jonah MM Cerny EA Rahman YE	Biochim Biophys Acta	1978 Jul 3	96869

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements