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G91237TK

Summary

GlyTouCan ID: G91237TK
IUPAC Condensed: Neu5Ac(a2-3)Gal(b1-4)Glc(b1-
Motifs: GM3
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 633.21

External Links

GlyGen

G91237TK

ChEBI

59226

PubChem Compound

5288424

PubChem Substance

252278045

3D Structures

GLYCAM: Neup5Aca2-3DGalpb1-4DGlcpb1-OH

GlycoShape

G91237TK

Displaying 1 entry
Archetype	α	β
G40764VP	G92323ZH	G91237TK

Organisms

Displaying entries **26 - 30** of 35 in total

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Organisms	Evidence
Cricetinae (hamsters)	GlyTouCan(glycome-db)
Rajidae (hardnose skates)	GlyTouCan(glycome-db)
Cavia porcellus (domestic guinea pig)	GlyTouCan(glycome-db)
Sus scrofa (pig)	GlyTouCan(glycome-db)
Papio hamadryas (hamadryas baboon)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Chondrichthyes (cartilaginous fishes) [inference]

Elasmobranchii (elasmobranchs) [inference]

Batoidea (rays) [inference]

Rajiformes (skates) [inference]

Rajidae (hardnose skates)

Leucoraja [inference]

Leucoraja erinacea (little skate)

Torpediniformes [inference]

Torpedinidae (electric rays) [inference]

Torpedo [inference]

Torpedo marmorata (marbled electric ray)

Narcinidae (numbfishes) [inference]

Discopyge [inference]

Discopyge tschudii (apron ray)

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Protacanthopterygii [inference]

Salmoniformes (salmons and trouts) [inference]

Salmonidae (salmonids) [inference]

Salmoninae (trouts, salmons & chars) [inference]

Oncorhynchus [inference]

Oncorhynchus mykiss (rainbow trout)

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Euacanthomorphacea [inference]

Percomorphaceae [inference]

Eupercaria [inference]

Perciformes (perches and others) [inference]

Notothenioidei [inference]

Channichthyidae (crocodile icefishes) [inference]

Chionodraco [inference]

Chionodraco myersi (Myers' icefish)

Nototheniidae (Antarctic cods) [inference]

Trematomus [inference]

Trematomus lepidorhinus (slender scalyhead)

Ovalentaria [inference]

Cichlomorphae [inference]

Cichliformes (cichlids and convict blennies) [inference]

Cichlidae (cichlids) [inference]

African cichlids [inference]

Pseudocrenilabrinae [inference]

Oreochromini [inference]

Oreochromis [inference]

Oreochromis mossambicus (Mozambique tilapia)

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus [inference]

Gadus morhua (Atlantic cod)

Otomorpha [inference]

Ostariophysi [inference]

Otophysi [inference]

Cypriniphysae [inference]

Cypriniformes (carps and others) [inference]

Cyprinoidei [inference]

Cyprinidae [inference]

Cyprininae [inference]

Carassius [inference]

Carassius auratus (goldfish)

Cyprinus [inference]

Cyprinus carpio (common carp)

Leuciscidae [inference]

Leuciscinae [inference]

Scardinius [inference]

Scardinius erythrophthalmus (rudd)

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Ovis aries (sheep)

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Feliformia [inference]

Felidae (cat family) [inference]

Felinae [inference]

Felis [inference]

Felis catus (domestic cat)

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Cricetidae [inference]

Cricetinae (hamsters)

Phodopus [inference]

Phodopus sungorus

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Hystricomorpha (guinea pigs and others) [inference]

Chinchillidae (chinchillas)

Chinchilla

Caviidae (cavies) [inference]

Cavia (guinea pigs) [inference]

Cavia porcellus (domestic guinea pig)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Platyrrhini (New World monkeys)

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Papio (baboons) [inference]

Papio hamadryas (hamadryas baboon)

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls) [inference]

Phasianidae (turkeys) [inference]

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Amphibia (amphibians) [inference]

Batrachia [inference]

Anura (frogs and toads) [inference]

Pipoidea [inference]

Pipidae (tongueless frogs) [inference]

Xenopodinae [inference]

Xenopus

Xenopus [inference]

Xenopus laevis (African clawed frog)

Bacteria (eubacteria) [inference]

Campylobacterota [inference]

Epsilonproteobacteria [inference]

Campylobacterales [inference]

Campylobacteraceae [inference]

Campylobacter [inference]

Campylobacter jejuni

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

GlycoGene Database (GGDB)

Displaying entries **1 - 5** of 6 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA1	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	8195250
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	11980897
ST8SIA3	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	7782326
ST3GAL5	CMP-Neu5Ac	G84224TW	ceramide	G91237TK	ceramide	9822625
B4GALNT2	UDP-GalNAc	G91237TK		G79389NT		12678917

Displaying entries **1 - 5** of 9 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA1	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	8195250 8910600
ST3GAL3	CMP-Neu5Ac	G84224TW	free	G91237TK	free	8288606
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	11980897
ST8SIA3	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	7782326 8910600
ST8SIA6	CMP-Neu5Ac	G91237TK		G98544DH		11980897

Displaying entries **1 - 5** of 8 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST8SIA2	CMP-Neu5Ac	G91237TK	Cer	7782326
ST8SIA5	CMP-Neu5Ac	G91237TK	Cer	8910600 9199191
ST3GAL6	CMP-Neu5Ac	G91237TK	ceramide	10206952
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	16120058
ST6GAL1	CMP-Neu5Ac	G91237TK	ceramide	12235148

KEGG BRITE Database

KEGG ID

G00108

Enzyme

References

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05940	2.4.3.8	G91237TK	G98544DH
R05937	2.4.3.9	G84224TW	G91237TK
R05939	2.4.1.92	G91237TK	G79389NT
R06004	3.2.1.52	G79389NT	G91237TK

GlycoEpitope

Epitope ID: EP0053

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n

WURCS

WURCS=2.0/3,3,2/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3/a4-b1_b3-c2

Literature

Displaying entries **21 - 30** of 55 in total

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PubMed ID	Title	First Author	Publication Date	Source
19124471	Enhancing the Receptor Affinity of the Sialic Acid-binding Domain of Vibrio cholerae Sialidase through Multivalency	Connaris H	2009 Mar 13	PubChem
18022638	Structural Implications of Siglec-5-Mediated Sialoglycan Recognition	Zhuravleva MA	2008 Jan 11	PubChem
17329247	Structural and Mechanistic Analyses of endo-Glycoceramidase II, a Membrane-associated Family 5 Glycosidase in the Apo and GM3 Ganglioside-bound Forms	Caines MEC	2007 May 11	PubChem
16621820	Mutation of waaC, encoding heptosyltransferase I in Campylobacter jejuni 81-176, affects the structure of both lipooligosaccharide and capsular carbohydrate	Kanipes MI	2006 May	BCSDB GlyGen
16120058	Molecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteins	Teintenier-Lelièvre M	2005 Dec 06	PubChem
16051274	Structural Basis of a Fungal Galectin from Agrocybe cylindracea for Recognizing Sialoconjugate	Ban M	2005 Aug 26	PubChem
12678917	Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain	Montiel MD	2003 Jul 15	PubChem
12235148	Characterization of the second type of human beta-galactoside alpha 2,6-sialyltransferase (ST6Gal II), which sialylates Galbeta 1,4GlcNAc structures on oligosaccharides preferentially. Genomic analysis of human sialyltransferase genes	Takashima S	2002 Nov 29	PubChem
11980897	Molecular cloning and expression of a sixth type of alpha 2,8-sialyltransferase (ST8Sia VI) that sialylates O-glycans	Takashima S	2002 Jul 05	PubChem
10747930	An Unusual Carbohydrate Binding Site Revealed by the Structures of Two Maackia amurensis Lectins Complexed with Sialic Acid-containing Oligosaccharides	Imberty A	2000 Jun 09	PubChem

PubAnnotation

Displaying entries **1 - 5** of 6 in total

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Title	Authors	Source	Publication Date	PubMed ID
High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients.	Wang Z Wen L Ma X Chen Z Yu Y Zhu J Wang Y Liu Z Liu H Wu D Zhou D Li Y	Glycobiology	2012 Jul	22411838
Studies of the carbohydrate-carbohydrate interaction between lactose and GM(3) using Langmuir monolayers and glycolipid micelles.	Santacroce PV Basu A	Glycoconj J	2004	15483375
Didecyl squarate--a practical amino-reactive cross-linking reagent for neoglycoconjugate synthesis.	Bergh A Magnusson BG Ohlsson J Wellmar U Nilsson UJ	Glycoconj J	2001 Aug	12376726
The total synthesis of ganglioside GM3.	Duclos RI Jr	Carbohydr Res	2000 Oct 6	11093705
Characterization of a CMP-sialic acid:lactosylceramide sialyltransferase activity in cultured hamster cells.	Burczak JD Fairley JL Sweeley CC	Biochim Biophys Acta	1984 Aug 17	6466712

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements