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G91237TK

Summary

GlyTouCan ID: G91237TK
IUPAC Condensed: Neu5Ac(a2-3)Gal(b1-4)Glc(b1-
Motifs: GM3
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 633.21

External Links

GlyGen

G91237TK

ChEBI

59226

PubChem Compound

5288424

PubChem Substance

252278045

3D Structures

GLYCAM: Neup5Aca2-3DGalpb1-4DGlcpb1-OH

GlycoShape

G91237TK

Displaying 1 entry
Archetype	α	β
G40764VP	G92323ZH	G91237TK

Organisms

Displaying entries **11 - 15** of 35 in total

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Organisms	Evidence
Rattus	GlyTouCan(glycome-db)
Escherichia coli	GlyTouCan(glycome-db)
Platyrrhini (New World monkeys)	GlyTouCan(glycome-db)
Chionodraco myersi (Myers' icefish)	GlyTouCan(glycome-db)
Phodopus sungorus	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Chondrichthyes (cartilaginous fishes) [inference]

Elasmobranchii (elasmobranchs) [inference]

Batoidea (rays) [inference]

Rajiformes (skates) [inference]

Rajidae (hardnose skates)

Leucoraja [inference]

Leucoraja erinacea (little skate)

Torpediniformes [inference]

Torpedinidae (electric rays) [inference]

Torpedo [inference]

Torpedo marmorata (marbled electric ray)

Narcinidae (numbfishes) [inference]

Discopyge [inference]

Discopyge tschudii (apron ray)

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Protacanthopterygii [inference]

Salmoniformes (salmons and trouts) [inference]

Salmonidae (salmonids) [inference]

Salmoninae (trouts, salmons & chars) [inference]

Oncorhynchus [inference]

Oncorhynchus mykiss (rainbow trout)

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Euacanthomorphacea [inference]

Percomorphaceae [inference]

Eupercaria [inference]

Perciformes (perches and others) [inference]

Notothenioidei [inference]

Channichthyidae (crocodile icefishes) [inference]

Chionodraco [inference]

Chionodraco myersi (Myers' icefish)

Nototheniidae (Antarctic cods) [inference]

Trematomus [inference]

Trematomus lepidorhinus (slender scalyhead)

Ovalentaria [inference]

Cichlomorphae [inference]

Cichliformes (cichlids and convict blennies) [inference]

Cichlidae (cichlids) [inference]

African cichlids [inference]

Pseudocrenilabrinae [inference]

Oreochromini [inference]

Oreochromis [inference]

Oreochromis mossambicus (Mozambique tilapia)

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus [inference]

Gadus morhua (Atlantic cod)

Otomorpha [inference]

Ostariophysi [inference]

Otophysi [inference]

Cypriniphysae [inference]

Cypriniformes (carps and others) [inference]

Cyprinoidei [inference]

Cyprinidae [inference]

Cyprininae [inference]

Carassius [inference]

Carassius auratus (goldfish)

Cyprinus [inference]

Cyprinus carpio (common carp)

Leuciscidae [inference]

Leuciscinae [inference]

Scardinius [inference]

Scardinius erythrophthalmus (rudd)

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Ovis aries (sheep)

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Feliformia [inference]

Felidae (cat family) [inference]

Felinae [inference]

Felis [inference]

Felis catus (domestic cat)

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Cricetidae [inference]

Cricetinae (hamsters)

Phodopus [inference]

Phodopus sungorus

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Hystricomorpha (guinea pigs and others) [inference]

Chinchillidae (chinchillas)

Chinchilla

Caviidae (cavies) [inference]

Cavia (guinea pigs) [inference]

Cavia porcellus (domestic guinea pig)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Platyrrhini (New World monkeys)

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Papio (baboons) [inference]

Papio hamadryas (hamadryas baboon)

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls) [inference]

Phasianidae (turkeys) [inference]

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Amphibia (amphibians) [inference]

Batrachia [inference]

Anura (frogs and toads) [inference]

Pipoidea [inference]

Pipidae (tongueless frogs) [inference]

Xenopodinae [inference]

Xenopus

Xenopus [inference]

Xenopus laevis (African clawed frog)

Bacteria (eubacteria) [inference]

Campylobacterota [inference]

Epsilonproteobacteria [inference]

Campylobacterales [inference]

Campylobacteraceae [inference]

Campylobacter [inference]

Campylobacter jejuni

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

GlycoGene Database (GGDB)

Displaying entries **1 - 5** of 6 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA1	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	8195250
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	11980897
ST8SIA3	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	7782326
ST3GAL5	CMP-Neu5Ac	G84224TW	ceramide	G91237TK	ceramide	9822625
B4GALNT2	UDP-GalNAc	G91237TK		G79389NT		12678917

Displaying entries **1 - 5** of 9 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
ST8SIA1	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	8195250 8910600
ST3GAL3	CMP-Neu5Ac	G84224TW	free	G91237TK	free	8288606
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	11980897
ST8SIA3	CMP-Neu5Ac	G91237TK	Cer	G98544DH	Cer	7782326 8910600
ST8SIA6	CMP-Neu5Ac	G91237TK		G98544DH		11980897

Displaying entries **1 - 5** of 8 in total

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST8SIA2	CMP-Neu5Ac	G91237TK	Cer	7782326
ST8SIA5	CMP-Neu5Ac	G91237TK	Cer	8910600 9199191
ST3GAL6	CMP-Neu5Ac	G91237TK	ceramide	10206952
ST8SIA6	CMP-Neu5Ac	G91237TK	Cer	16120058
ST6GAL1	CMP-Neu5Ac	G91237TK	ceramide	12235148

KEGG BRITE Database

KEGG ID

G00108

Enzyme

References

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05940	2.4.3.8	G91237TK	G98544DH
R05937	2.4.3.9	G84224TW	G91237TK
R05939	2.4.1.92	G91237TK	G79389NT
R06004	3.2.1.52	G79389NT	G91237TK

GlycoEpitope

Epitope ID: EP0053

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n

WURCS

WURCS=2.0/3,3,2/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3/a4-b1_b3-c2

Literature

Displaying entries **51 - 55** of 55 in total

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PubMed ID	Title	First Author	Publication Date	Source
2231724	2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES	Wright CS	1990 Oct 15	PubChem
2908845	Two human monoclonal antibodies reacting with the major gangliosides of human melanomas and comparison with corresponding mouse monoclonal antibodies	Furukawa K	1989 Jan 01	GlyGen GlycoEpitope
3167827	An IgG3 monoclonal antibody established after immunization with GM3 lactone: immunochemical specificity and inhibition of melanoma cell growth in vitro and in vivo	Dohi T	1988 Oct 15	GlyGen GlycoEpitope
3031684	Cell-surface antigens of melanoma recognized by human monoclonal antibodies	Yamaguchi H	1987 Apr	GlyGen GlycoEpitope
2414279	Syngeneic monoclonal antibody against melanoma antigen with interspecies cross-reactivity recognizes GM3, a prominent ganglioside of B16 melanoma	Hirabayashi Y	1985 Oct 25	GlyGen GlycoEpitope

PubAnnotation

Displaying entries **1 - 5** of 6 in total

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Title	Authors	Source	Publication Date	PubMed ID
High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients.	Wang Z Wen L Ma X Chen Z Yu Y Zhu J Wang Y Liu Z Liu H Wu D Zhou D Li Y	Glycobiology	2012 Jul	22411838
Studies of the carbohydrate-carbohydrate interaction between lactose and GM(3) using Langmuir monolayers and glycolipid micelles.	Santacroce PV Basu A	Glycoconj J	2004	15483375
Didecyl squarate--a practical amino-reactive cross-linking reagent for neoglycoconjugate synthesis.	Bergh A Magnusson BG Ohlsson J Wellmar U Nilsson UJ	Glycoconj J	2001 Aug	12376726
The total synthesis of ganglioside GM3.	Duclos RI Jr	Carbohydr Res	2000 Oct 6	11093705
Characterization of a CMP-sialic acid:lactosylceramide sialyltransferase activity in cultured hamster cells.	Burczak JD Fairley JL Sweeley CC	Biochim Biophys Acta	1984 Aug 17	6466712

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements