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G98544DH

Summary
GlyTouCan ID
G98544DH
IUPAC Condensed
Neu5Ac(a2-8)Neu5Ac(a2-3)Gal(b1-4)Glc(b1-
Motifs
9-O-Acetyl GD3 GD3
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
924.31
GlyGen
ChEBI
PubChem Compound
PubChem Substance
3D Structures
GLYCAM
Neup5Aca2-8Neup5Aca2-3DGalpb1-4DGlcpb1-OH
GlycoShape
G98544DH
Displaying 1 entry
Archetype α β
G10158SF
G58409WK
G98544DH
Organisms
Displaying entries 1 - 5 of 24 in total
Organisms Evidence
Felis catus (domestic cat)
Macaca fuscata (Japanese macaque)
Carassius auratus (goldfish)
Torpedo marmorata (marbled electric ray)
Mus musculus (house mouse)
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST8SIA1 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
ST8SIA6 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
ST8SIA3 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
ST8SIA5 CMP-Neu5Ac
G98544DH
Cer
G93899SO
Cer
Displaying entries 1 - 5 of 7 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST8SIA1 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
ST8SIA6 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
ST8SIA3 CMP-Neu5Ac
G98544DH
Cer
G93899SO
Cer
ST8SIA3 CMP-Neu5Ac
G91237TK
Cer
G98544DH
Cer
ST8SIA6 CMP-Neu5Ac
G91237TK
G98544DH
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST8SIA2 CMP-Neu5Ac
G98544DH
Cer
ST8SIA6 CMP-Neu5Ac
G98544DH
Cer
ST8SIA1 CMP-Neu5Ac
G98544DH
Cer
B4GALNT2 UDP-GalNAc
G98544DH
Cer
B3GALNT1 UDP-GalNAc
G98544DH
Cer
KEGG BRITE Database
KEGG ID
Enzyme
Reactions
Displaying all 3 entries
KEGG Reaction Enzyme Acceptor Product
R05946
R05947
R05940
GlycoEpitope
Epitope ID
EP0062
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:3o(8+2)5d
5:5d(5+1)6n
WURCS
WURCS=2.0/3,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-3/a4-b1_b3-c2_c8-d2
Literature
Displaying entries 41 - 48 of 48 in total
PubMed ID Title First Author Publication Date Source
3791209 Fluctuations in the expression of a glycolipid antigen associated with differentiation of melanoma cells monitored by a monoclonal antibody, Leo Mel 3 Werkmeister JA 1987 Jan 01
  • GlyGen
  • GlycoEpitope
2435716 Monoclonal antibody Leo Mel 3, which inhibits killing of human melanoma cells by anomalous killer cells, binds to a sugar sequence in GD2 (II3(NeuAc)2-GgOse3Cer) and several other gangliosides Fukuta S 1987 Apr 05
  • GlyGen
  • GlycoEpitope
3031684 Cell-surface antigens of melanoma recognized by human monoclonal antibodies Yamaguchi H 1987 Apr
  • GlyGen
  • GlycoEpitope
3019521 Biosynthesis and expression of the disialoganglioside GD2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis Cheresh DA 1986 Oct
  • GlyGen
  • GlycoEpitope
3005335 Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins Cheresh DA 1986 Mar
  • GlyGen
  • GlycoEpitope
3840699 Mouse monoclonal antibodies with specificity for the melanoma-associated ganglioside disialyllactosylceramide (GD3) also react with the structural analogue disialylparagloboside Brodin T 1985 Dec 04
  • GlyGen
  • GlycoEpitope
6385004 Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells Cheresh DA 1984 Sep
  • GlyGen
  • GlycoEpitope
7061953 GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody Pukel CS 1982 Apr 01
  • GlyGen
  • GlycoEpitope
PubAnnotation
Displaying entries 1 - 5 of 7 in total
Title Authors Source Publication Date PubMed ID
Tissue-specific expression of GM3(NeuGc) and GD3(NeuGc) in epithelial cells of the small intestine of strains of inbred rats. Absence of NeuGc in intestine and presence in kidney gangliosides of brown Norway and spontaneously hypertensive rats.
  • Bouhours D
  • Bouhours JF
 J Biol Chem 1988 Oct 25 3170597
Analysis of the expression of N-glycolylneuraminic acid-containing gangliosides in cells and tissues using two human monoclonal antibodies.
  • Furukawa K
  • Yamaguchi H
  • Oettgen HF
  • Old LJ
  • Lloyd KO
 J Biol Chem 1988 Dec 5 3192544
Monoclonal antibody detects monosialogangliosides having a sialic acid alpha 2----3-galactosyl residue.
  • Tai T
  • Sze L
  • Kawashima I
  • Saxton RE
  • Irie RF
 J Biol Chem 1987 May 15 3571288
Monoclonal antibody Leo Mel 3, which inhibits killing of human melanoma cells by anomalous killer cells, binds to a sugar sequence in GD2 (II3(NeuAc)2-GgOse3Cer) and several other gangliosides.
  • Fukuta S
  • Werkmeister JA
  • Burns GF
  • Ginsburg V
  • Magnani JL
 J Biol Chem 1987 Apr 5 2435716
Glycosphingolipids of leukemic cells in adult T-cell leukemia-lymphoma.
  • Kuriyama M
  • Nomura K
  • Tara M
  • Matsubara H
  • Igata A
 Biochim Biophys Acta 1985 May 17 2986706
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