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NAD(P)H oxidase (H2O2-forming)

Summary

UniProt ID: O01795
Gene Symbol: CELE_F53G12.3 F53G12.3 duox-2
Gene ID: 186188
Organism: Caenorhabditis elegans

External Links

GlycoProtDB: GPDB0000395
Re-Glyco: O01795

Annotation

Keyword: Calcium FAD Glycoprotein Heme Hydrogen peroxide NADP Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
defense response	IBA	GO_REF
response to oxidative stress	IEA	GO_REF
post-embryonic body morphogenesis	IMP	PMID
cuticle development involved in collagen and cuticulin-based cuticle molting cycle	IMP	PMID
superoxide anion generation	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

hydrogen peroxide catabolic process

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

superoxide anion generation

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

developmental process [inference]

anatomical structure morphogenesis [inference]

post-embryonic animal morphogenesis [inference]

post-embryonic body morphogenesis

body morphogenesis [inference]

post-embryonic body morphogenesis

anatomical structure development [inference]

cuticle development [inference]

collagen and cuticulin-based cuticle development [inference]

cuticle development involved in collagen and cuticulin-based cuticle molting cycle

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response

defense response to bacterium

response to oxidative stress

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

Displaying **all 2** entries
GO Term	Evidence Code	Reference
plasma membrane
NADPH oxidase complex	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

NADPH oxidase complex

catalytic complex [inference]

oxidoreductase complex [inference]

NADPH oxidase complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
peroxidase activity	IEA	GO_REF GO_REF
calcium ion binding	IEA	GO_REF
NAD(P)H oxidase H2O2-forming activity	IBA	GO_REF
NAD(P)H oxidase H2O2-forming activity	IEA	GO_REF GO_REF
superoxide-generating NAD(P)H oxidase activity	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on NAD(P)H [inference]

oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [inference]

oxidoreductase activity, acting on peroxide as acceptor [inference]

peroxidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

tetrapyrrole binding [inference]

heme binding

antioxidant activity [inference]

peroxidase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAAENFYNVNNFQSLPLEIKVQFSKETLFSALQQEAETQRYDGWYNNLANSEWGSAGSRLHRDARSYYSDGVYSVNNSLPSARELSDILFKGESGIPNTRGCTTLLAFFSQVVAYEIMQSNGVSCPLETLKIQVPLCDNVFDNECEGKTTIPFYRAKYDKATGNGLNSPREQINERTSWIDGSFIYGTTQPWVSALRSFKQGRLAEGVPGYPPLNNPHIPLNNPAPPQVHRLMSPDRLFMLGDSRVNENPGLLSFGLILFRWHNYNANQIYREHPDWTDEQIFQAARRLVIASMQKIIAYDFVPGLLGEDVRLSNYTKYMPHVPPGISHAFGAAAFRFPHSIVPPAMLLRKRGNKCEFRTEVGGYPALRLCQNWWNAQDIVKEYSVDEIILGMASQIAERDDNIVVEDLRDYIFGPMHFSRLDVVASSIMRGRDNGVPPYNELRRTFGLAPKTWETMNEDFYKKHTAKVEKLKELYGGNILYLDAYVGGMLEGGENGPGEMFKEIIKDQFTRIRDGDRFWFENKLNRLFTDEEVQMIHSITLRDIIKATTDIDETMLQKDVFFFKEGDPCPQPFQVNTIGLEPCAPLIQSTYWDDNDTTYIYTLIGLACIPLICYSIGHYMVERRIRIGHNSACDSLTTDFSTESPKVNVYKVNALEWLQEEYIRQVRIEIENTTLTVKKPRGGILRKIRFETGQKIEVFHSIPNPSAMHGPFVLLSQKNNHHLVIRLSSDRDLSKFLDQIRQAASGINAEVIIKDEENSILLSQAITKERRQDRLDLFFREAYAKAFNDSELQDSETSFDSSNDDILNETISREELASAMGMKANNEFVKRMFAMTAKHNEDSLSFNEFLTVLREFVNAPQKQKLQTLFKMCDLEGKNKVLRKDLAELVKSLNQTAGVHITESVQLRLFNDVLHKSGVSDDAEYLTCNNFDALFSEISDVQPIGLPFNRKNYNSHIKEPSCHTSFPIVDHSTPAPLSLIQRICAFLETYRQHVFIIFCFVAINIVLFFELFWHSRYLNEDRDLRRVMGAGIAITLSSAGALSFCMALILLTVCRNIITLLRETVIAQYIPFDSAIAFHKIVALFTLFWSTLHTIGHCVNFYHVGTQSDRGLACLFQETFFGSDVVPTLSYWFYGTITGLTGIGLVIVMSIIYVFALPKFTRRAYHAFRLTHLLNIGFYALTILHGLPSLFGSPKFGYYVVGPIVLFVIDRIIGLMQYYKSLDIAHAEILPSDIIYIEYRRPREFEYKSGQWITVSSPSISCTFNESHAFSIASSPQDENMKLYIKAVGPWTWKLRSELIRSLNTGSPFPLIHMKGPYGDGNQEWMNYEVAIMVGAGIGVTPYASTLVDLVQKTSSDSFHRVRCRKVYFLWVCSSHKNFEWFVDMLKNVENQAKPGILETHIFVTQMFHKFDLRTTMLYICEKHFRATNSGISMFTGLHAKNHFGRPNFKAFFQFIQSEHKEQSEIGVFSCGPVNLNESIAEGCADANRQRDAPSFAHRFETF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
76				GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Thyroxine biosynthesis	Caenorhabditis elegans

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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