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Protein phosphatase 1D

Summary

UniProt ID

O15297

Gene Symbol

PPM1D
WIP1

Gene ID

8493

Organism

Homo sapiens (human)

External Links

GlyGen: O15297
PubChem: O15297
The Human Metabolome Database: HMDBP08794
The O-GlcNAc Database: O15297
O-GlcNAcAtlas: O15297
Re-Glyco: O15297

Annotation

Keyword

Alternative splicing
Autism spectrum disorder
Cell cycle
Cytoplasm
Disease variant
Intellectual disability
Magnesium
Manganese
Metal-binding
Nucleus
Phosphoprotein
Protein phosphatase
Reference proteome

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
nucleus
nucleolus
nucleoplasm
cytosol

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 12 in total

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GO Term
DNA damage response, signal transduction by p53 class mediator
peptidyl-threonine dephosphorylation
cellular response to starvation
G2/M transition of mitotic cell cycle
DNA methylation-dependent heterochromatin formation
protein dephosphorylation
negative regulation of gene expression, epigenetic
regulation of transcription initiation by RNA polymerase II
regulation of intracellular signal transduction
negative regulation of cell population proliferation

Displaying entries **1 - 10** of 13 in total

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GO Term
MAP kinase serine/threonine phosphatase activity
histone H2AXS140 phosphatase activity
RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity
RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity
RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity
RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity
RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity
protein serine/threonine kinase activity
protein serine/threonine phosphatase activity
myosin phosphatase activity

Annotation information from UniProt.

Sequence

MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDNQGNFTNEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVKSLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAEIARENVQGVVIPSKDPEPLEENCAKALTLRIHDSLNNSLPIGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEESNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLLHQHRKTVCVC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites