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Fibroblast growth factor 10

Summary

UniProt ID

O15520

Gene Symbol

FGF10

Gene ID

2255

Organism

Homo sapiens (human)

External Links

PubChem: O15520
Re-Glyco: O15520

Annotation

Keyword

3D-structure
Disease variant
Glycoprotein
Growth factor
Lacrimo-auriculo-dento-digital syndrome
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
extracellular region
extracellular space
nucleus
cytoplasm
plasma membrane
cell surface

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
lung epithelium development
angiogenesis
positive regulation of cell population proliferation
neurogenesis
regulation of cell migration
establishment of mitotic spindle orientation
organ induction
positive regulation of endothelial cell proliferation
determination of left/right symmetry
positive regulation of epithelial cell migration

Displaying **all 5** entries
GO Term
growth factor activity
fibroblast growth factor receptor binding
heparin binding
type 2 fibroblast growth factor receptor binding
chemoattractant activity

Annotation information from UniProt.

Sequence

MWKWILTHCASAFPHLPGCCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
51	N-linked (GlcNAc...) asparagine			UniProt
196	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 22 in total

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Pathway Name	Organism
Activated point mutants of FGFR2	Homo sapiens
Constitutive Signaling by Aberrant PI3K in Cancer	Homo sapiens
Downstream signaling of activated FGFR1	Homo sapiens
FGFR1b ligand binding and activation	Homo sapiens
FGFR2b ligand binding and activation	Homo sapiens
FGFRL1 modulation of FGFR1 signaling	Homo sapiens
FRS-mediated FGFR1 signaling	Homo sapiens
FRS-mediated FGFR2 signaling	Homo sapiens
Negative regulation of FGFR1 signaling	Homo sapiens
Negative regulation of FGFR2 signaling	Homo sapiens

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0081372	lacrimoauriculodentodigital syndrome 3	Alliance of Genome Resources
DOID:0111549	aplasia of lacrimal and salivary glands	Alliance of Genome Resources