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MIRAGE
Activated point mutants of FGFR2

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATPADPFGFR2b mutant dimers with enhanced ligand-binding bound to FGFsActivated FGFR2b mutants with enhanced ligand bindingFGFR2 ligand-independent mutantsFGFR2 ligand-independent mutant dimersActivated FGFR2 ligand-independent mutantsFGFR2b mutant-binding FGFsFGFR2b mutants with enhanced ligand bindingHSFP-1039FGFR2b mutant-binding FGFs:FP-1039FGFR2c mutant dimers with enhanced ligand-binding bound to FGFsFGFR2c mutants with enhanced ligand bindingFGFR2c mutant binding FGFsActivated FGFR2c mutants with enhanced ligand-bindingFGFR2 mutants with enhanced kinase activityFGFR2 mutant dimers with enhanced kinase activityActivated FGFR2 mutants with enhanced kinase activityFGFR2 point mutant dimersFGFR2 point mutant dimers:TKIsTyrosine kinase inhibitors of FGFR2 mutants
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025